Protein Overview: SPBC336.02

General Information:
Name(s) found:	SPBC336.02 [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	pir\|\|T40240 dimethylase - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|6048291\|emb\|CAB58154.1\| 18S rRNA dimethylase [Schizosaccharomyces pombe] [NCBI NR] gi\|26556992\|sp\|Q9USU2.1\|DIM1_SCHPO RecName: Full=Dimethyladenosine transferase; AltName: Full=S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase; AltName: Full=18S rRNA dimethylase [NCBI NR] gi\|19112914\|ref\|NP_596122.1\| 18S rRNA dimethylase [Schizosaccharomyces pombe] [NCBI NR] 18S rRNA dimethylase [Sanger Pombe] Dimethyladenosine transferase OS=Schizosaccharomyces pombe GN=dim1 PE=2 SV=1 [Swiss-Prot] DIMETHYLASE: Q9Y7V3; [pompepVF.fasta] Dimethyladenosine transferase (EC 2.1.1.-) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [pompep4896] \|dim1\|\|dimethylase [pompepnew.fasta] \|dim1\|\|methylase\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] dimethylase [Schizosaccharomyces pombe]gi\|6048291\|emb\|CAB58154.1\| dim1 [Schizosaccharomyces pombe]gi\|26556992\|sp\|Q9USU2\|DIM1_SCHPO Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase)gi [nrdb_11152004_Chlamydomonas] \|\|\|methylase\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pompep2242005.fasta] (Q9USU2) Dimethyladenosine transferase (EC 2.1.1.-) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [pompep4896_normal_reversed] \|\|\|18S rRNA dimethylase\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] hypothetical protein SPBC336.02 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] SPBC336.02 [Schizosaccharomyces pombe] [nr-271106-contam.fasta] Dimethyladenosine transferase (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase) (18S rRNA dimethylase) [nr-271106-contam.fasta] \|\|\|18S rRNA dimethylase \|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [Other_S_Pombe_12-15-2011_reversed.fasta] Dimethyladenosine transferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dim1 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	307 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] spindle [IDA] nucleolus [IDA][ISS]
Biological Process:	rRNA modification [ISS] rRNA processing [ISS]
Molecular Function:	RNA binding [IEA] rRNA (adenine-N6,N6-)-dimethyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKIRVRNNN AASDAEVRNT VFKFNKDFGQ HILKNPLVAQ GIVDKADLKQ SDTVLEVGPG  60
   61 TGNLTVRMLE KARKVIAVEM DPRMAAEITK RVQGTPKEKK LQVVLGDVIK TDLPYFDVCV 120
  121 SNTPYQISSP LVFKLLQQRP APRAAILMFQ REFALRLVAR PGDPLYCRLS ANVQMWAHVK 180
  181 HIMKVGKNNF RPPPLVESSV VRIEPKNPPP PLAFEEWDGL LRIVFLRKNK TIGACFKTSS 240
  241 IIEMVENNYR TWCSQNERMV EEDFDVKSLI DGVLQQCNLQ DARASKCGQT EFLSLLHAFH 300
  301 QVGVHFA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

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Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
rRNA methyltransferase activity	4.09362182773099	bayes_pls_golite062009
N-methyltransferase activity	4.00768472859991	bayes_pls_golite062009
methyltransferase activity	3.57681394097837	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.49392219433935	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	2.00108769169811	bayes_pls_golite062009
RNA binding	1.99752836873461	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	1.83964463328968	bayes_pls_golite062009
tRNA methyltransferase activity	1.76571145896453	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	1.75675289134467	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
protein methyltransferase activity	0.94499223839747	bayes_pls_golite062009
transcription regulator activity	0.914549843668268	bayes_pls_golite062009
rRNA (uridine-2'-O-)-methyltransferase activity	0.90544396691236	bayes_pls_golite062009
DNA binding	0.86027591375666	bayes_pls_golite062009
binding	0.777596419415505	bayes_pls_golite062009
rRNA (uridine) methyltransferase activity	0.742142092552002	bayes_pls_golite062009
nucleic acid binding	0.616949327277483	bayes_pls_golite062009
mRNA binding	0.0540207721800283	bayes_pls_golite062009
histone methyltransferase activity	0.0408000230099101	bayes_pls_golite062009
snoRNA binding	0.00848192089639488	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..307]	PSI-BLAST	63.221849	Crystal structure of human Dimethyladenosine transferase

Protein Overview: SPBC336.02

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: