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Protein Overview: cys12

General Information:
Name(s) found: cys12 / SPAC3A12.17c [Sanger Pombe]
Description(s) found:
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  • pir||T38685 probable cysteine synthase (EC 4.2.99.8) SPAC3A12.17c [similarity] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|3219785|sp|P87131.1|CYSK2_SCHPO RecName: Full=Cysteine synthase 2; Short=CSase 2; AltName: Full=O-acetylserine sulfhydrylase 2; AltName: Full=O-acetylserine (thiol)-lyase 2; Short=OAS-TL 2 [NCBI NR]
  • gi|2104433|emb|CAB08745.1| cysteine synthase Cys12 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114255|ref|NP_593343.1| cysteine synthase Cys12 [Schizosaccharomyces pombe] [NCBI NR]
  • cysteine synthase Cys12 [Sanger Pombe]
  • (P87131) Putative cysteine synthase (EC 2.5.1.47) (O-acetylserine sulfhydrylase) (O-acetylserine (Thiol)-lyase) (CSase) [Swiss-Prot]
  • Cysteine synthase 2 OS=Schizosaccharomyces pombe GN=cys12 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE CYSTEINE SYNTHASE: P87131; [pompepVF.fasta]
  • Putative cysteine synthase (EC 2.5.1.47) (O-acetylserine sulfhydrylase) (O-acetylserine (Thiol)-lyase) (CSase) [pompep4896]
  • |||putative cysteine synthase [pompepnew.fasta]
  • |cys12|cys1b|cysteine synthase|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative cysteine synthase [Schizosaccharomyces pombe]gi|2104433|emb|CAB08745.1| cysteine synthase; not involved in cysteine metabolism under normal growth conditions (PMID 14981292); similar to S. cerevisiae YGR012W [Schizosaccharomyces pombe]gi|321978 [nrdb_11152004_Chlamydomonas]
  • |cys12|cys1b|cysteine synthase Cys12|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC3A12.17c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Cysteine synthase 2 (O-acetylserine sulfhydrylase 2) (O-acetylserine (Thiol)-lyase 2) (CSase 2) [nr-271106-contam.fasta]
  • hypothetical protein SPAC3A12.17c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Cysteine synthase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cys12 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 395 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: [NOT]cysteine biosynthetic process from serine [IMPLink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEA]
    [NOT]cysteine synthase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKYQDLAS GIAMGAVFMY LLRRLYESLR VKSSADSLEE DIVNGVEGLI GNTKMVRIKS  60
   61 LSQATGCDIL AKAEFLNPGN SPKDRVALQM IRTAEENGDL VPYQSNAVYE GTAGSTGISI 120
  121 AMLCCSLGYD SRIYMPSDQS KEKSDILELL GAHVQRVTPA PIVDPNHFVN TARRNAANHT 180
  181 VDESIPGKGY FANQFENPAN WQAHFNSTGP EIWRQCAGKL DAFIAGSGTG GTIAGISRYL 240
  241 KSKDPSITVC LADPPGSGLY HKVLHGVMFD LAEREGTRRR HQVDTIVEGV GINRMTRNFS 300
  301 IAEPLIDMAY RVTDEQAVAM SRYLVTHDGL FVGSSSAVNC VAAVRLAKKL GPGHRIVTLL 360
  361 CDPGSRHFSK LYNEEFLRKK NIVPQVPSSL DFVEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..395] PSI-BLAST 76.69897 Cystathionine beta-synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cysteine synthase activity
    		•  5.18562032111987 bayes_pls_golite062009
  • catalytic activity
    		•  2.38994231321972 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • cystathionine beta-synthase activity
    		•  1.4517088142802 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.04832999357666 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • threonine synthase activity
    		•  0.727838845253199 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  0.37325071016009 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.59

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle