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Protein Overview: cyr1

General Information:
Name(s) found: cyr1 / SPBC19C7.03 [Sanger Pombe]
Description(s) found:
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  • gi|3218407|emb|CAA19571.1| adenylate cyclase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19112951|ref|NP_596159.1| adenylate cyclase [Schizosaccharomyces pombe] [NCBI NR]
  • gi|173379|gb|AAA35301.1| adenylate cyclase [NCBI NR]
  • gi|173339|gb|AAA35284.1| adenylyl cyclase [NCBI NR]
  • gi|117794|sp|P14605.1|CYAA_SCHPO RecName: Full=Adenylate cyclase; AltName: Full=ATP pyrophosphate-lyase; AltName: Full=Adenylyl cyclase [NCBI NR]
  • pir||A33988 adenylate cyclase (EC 4.6.1.1) - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • adenylate cyclase [Sanger Pombe]
  • Adenylate cyclase OS=Schizosaccharomyces pombe GN=cyr1 PE=1 SV=1 [Swiss-Prot]
  • ADENYLATE CYCLASE; SIMILAR TO S. CEREVISIAE CYR1: P14605; [pompepVF.fasta]
  • ADENYLATE CYCLASE: P14605; [pompepV13]
  • Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase) [pompep4896]
  • |cyr1|git2|adenylate cyclase [pompepnew.fasta]
  • |cyr1|git2|adenylate cyclase activity|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • adenylate cyclase [Schizosaccharomyces pombe]gi|3218407|emb|CAA19571.1| cyr1 [Schizosaccharomyces pombe]gi|117794|sp|P14605|CYAA_SCHPO Adenylate cyclase (ATP pyrophosphate-lyase) (Adenylyl cyclase)gi|101011|pir||A33988 adenylate cyclase (EC 4.6.1.1) - [nrdb_11152004_Chlamydomonas]
  • (P14605) Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase) [pompep4896_normal_reversed]
  • |cyr1|git2|adenylate cyclase|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPBC19C7.03 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • adenylyl cyclase [nr-271106-contam.fasta]
  • SPBC19C7.03 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Adenylate cyclase (ATP pyrophosphate-lyase) (Adenylyl cyclase) [nr-271106-contam.fasta]
  • Adenylate cyclase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cyr1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 1692 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [NASLink to PubMed article]
    Biological Process: cAMP biosynthetic process [IMPLink to PubMed article]
    negative regulation of transcription by glucose [TASLink to PubMed article]
    G-protein signaling, coupled to cAMP nucleotide second messenger [NASLink to PubMed article]
    cAMP-mediated signaling [TASLink to PubMed article]
    regulation of conjugation with cellular fusion [NASLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    ATP binding [IEA]
    protein binding [IPILink to PubMed article]
    adenylate cyclase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQSKRLLKS AVPNPPEHFK TGISWLDDLD EKDDDSATSV NYDIPEITEA NLCNDSHEAL  60
   61 SPCTQPVGNS GRPVEAFKTY PSTPAVPSKS VLFHFYEPDE NFSLSDTGRT KSDTALAARE 120
  121 SSEKSEVPRD TRSAGIKPYK ENNSSNCAIS KEAGLRRLID KDRESFDKNL NQSFTNLTFP 180
  181 EPISDDSDSV EFQRDSLNNN WPASLEGSIH ELPRNSDDDG IPASAAHILD LDYHRDSYDS 240
  241 PWKKFLPYPS ILSDDSWKAP ESWGTSLPTE AIPKQVFTTR FFARPSLGNR KKEFFLRVYR 300
  301 DDRTSVSFIC PIGIQTHEVI KLLARLFFLP SSANFYLLLI QFNTERILLP HEQPCIIFER 360
  361 LLSLFGCKVT SDEEINEEDN YSVARLVFTT MDIGADVLRK FSEKKITANL DISRSNLEVI 420
  421 PVKIYPYAHE LISLNVSHNL SLDLPLDFME RCVKLKRLDI SNNLRSPRGK PITALRQLEV 480
  481 LNMSRNDIYE LDPLIFSGLS RNSLKELNIA NNKLFFLPHS TRYLVNLTYL DLSYNNFVTF 540
  541 PLIITELSQL ETLNFSHNLL SQISSKIGSL VKLKHLYLQF NDLSNRLPQE IGLLKNLETI 600
  601 DLSYNAITNI ASLSECPKLN SINVACNLLS FYEYSNPSAT FIDFSFCPLT TIDPAFSYSN 660
  661 LVYFDISHAK LIGLKDSVIE TLVNVETVKV NYNHFTSISD AISAMQNLKY LSCTNCEMSY 720
  721 VSPNLGKLKH LVHLDLHANN IKIFPEEVWQ VSSLKVVNLS SNILEKIKLP VATSKKLTRT 780
  781 ISQLKIMRTL SGNPVSSLSS QEFVMPTVEE LYLVDNRLGN DCFTALEYFK CLKVLNLSYN 840
  841 YLTEIPSKFF QNFSDLKHLF VSGNELANLS ISSTAQVLLE TLYANGNRLS SFPKNEALSK 900
  901 SLRFLDISTN NLQNLAVEKA EKKSLTKLPQ LEYLNLSGNT WFRFSEHEDT NFTKSYLKNL 960
  961 KFLSIMDLNT KFSNAPSDVL NHFIQRNSPQ PNILRYGVCG YLSRSIPVIS ACELVVNNFL1020
 1021 HPQSSLYCVL DSDISAGKNN RVLKFVYDNL ASCLAHEINA ADSSSEQICN ALRRGFLRLN1080
 1081 KKLGNVIHYD LRKSSEGDVD SNYVTTMNIS EKGYSMDSSC LDIGVSIILV YVRDTRAFVA1140
 1141 NVGTSMAIMS TRNDSEPTTL SVMHDVYNRD EIRRIVDSCG FISGEIKSTT TRAIGRLSQF1200
 1201 PGVQAVPYVN VQYLSELNEF IILANQEFWS VLSKRTVIDV VRANRHSPLL ASTKLRDYAI1260
 1261 AYGAEKNVLV VIVELNGLFE ENSLNFNQLR GDEKTLAISE KNDNMSFVQD LPDDSSLARM1320
 1321 NREVSPPKGC IAMVFTDIKN STLLWERHPI AMRSAIKTHN TIMRRQLRAT GGYEVKTEGD1380
 1381 AFMVCFQTVP AALLWCFSVQ LQLLSADWPN EIVESVQGRL VLGSKNEVLY RGLSVRIGVN1440
 1441 YGVTVSELDP ITRRMDYYGP VVNRTSRVVS VADGGQIAVS AEVVSVLNQL DSETMSSEKT1500
 1501 NVNEMEVRAL KQIGYIIHNL GEFKLKGLDT TEMISLVYPV QLQGRLERLI KSRSLGTPTA1560
 1561 LPETQTYTPV RSRSNSLRPM LARLSDSKSV HGEEGGSGKR SVSSLRNVSP SESTGGYEGC1620
 1621 IFDDQQYQLL YELCERLEDH AAILHGFPEP PPCDTGLAAP VNQAEEYSLF YRLTLRIENT1680
 1681 IYCVSQMLGH TG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle