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Protein Overview: ada1

General Information:
Name(s) found: ada1 / SPBC106.04 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • adenosine deaminase Ada1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 846 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: IMP biosynthetic process [ISSLink to PubMed article]
    cellular nitrogen compound metabolic process [ICLink to PubMed article]
    purine base metabolic process [IEA]
    Molecular Function: AMP deaminase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRPLSLCG LLPAEMNMEQ EDDQVPAVAA ETVPLKRYVT NPGANRDEEV AAAPSSQDTP  60
   61 YFDYAYERSL RHQDAKFLAM NGTQNGRDGL PSKSPRRPSV SASTVRNSDD VNHSKAGPGS 120
  121 GKLLNDTLQS KISSIHMPHV QQGDNAVVSS VGGPETDPGN METTDPLFSD ELAEIYLSIH 180
  181 KCMDMRHKYI RVSLQGELDN PIDDDSWIIY PDCKEGEDDT GLFNFADCKI PGIENEMEYH 240
  241 MDHQGIFQVY ENDSAYIAGT PSFHIPTIRD YYIDLEFLLS ASSDGPSKSF SFRRLQYLEG 300
  301 RWNMYMLLNE YQELADTKKV PHRDFYNVRK VDTHVHHSAL ANQKHLLRFI KAKLRKCPNE 360
  361 KVIWRDGKFL TLQEVFDSLK LTSYDLSIDT LDMHAHTDTF HRFDKFNLKY NPIGESRLRT 420
  421 IFLKTDNDIN GRYLAELTKE VFTDLRTQKY QMAEYRISIY GRNREEWDKL AAWIIDNELF 480
  481 SPNVRWLIQV PRLYDVYKKS GIVETFEEVV RNVFEPLFEV TKDPRTHPKL HVFLQRVIGF 540
  541 DSVDDESKPE RRTFRKFPYP KHWDINLNPP YSYWLYYMYA NMTSLNSWRK IRGFNTFVLR 600
  601 PHCGEAGDTD HLASAFLLSH GINHGILLRK VPFLQYLWYL DQIPIAMSPL SNNALFLAYD 660
  661 KNPFLTYFKR GLNVSLSTDD PLQFAFTREP LIEEYAVAAQ IYKLSAVDMC ELARNSVLQS 720
  721 GFERQLKERW LGVDFQDIDR TNVPIIRLAY RALTLTQEIA LVNKHVQPSK HPSNHDLEEL 780
  781 IHKYDAMTGT SDPLSASPRT NDATISSRLS LHDGHDHGAF FPGLSVISER RRRKDSMASS 840
  841 SQDLKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..774] PSI-BLAST 1000.0 X-Ray Structure of Adenosine 5'-Monophosphate Deaminase from Arabidopsis Thaliana in Complex with Coformycin 5'-Phosphate
    2 View Details [775..846] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.70199291046899 bayes_pls_golite062009
  • hydrolase activity
    		•  1.30610496460396 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.882933203153461 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
    		•  0.248802326836448 bayes_pls_golite062009
  • dihydroorotase activity
    		•  0.203044795244555 bayes_pls_golite062009
  • deaminase activity
    		•  0.18698811376434 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  0.0954028693917728 bayes_pls_golite062009
  • binding
    		•  0.014147565583623 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.51

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle