YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: alp14

General Information:
Name(s) found: alp14 / SPCC895.07 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
SHOW ALL
  • Mad2-dependent spindle checkpoint component [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 809 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    microtubule cytoskeleton [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed articleLink to PubMed article]
    condensed nuclear chromosome kinetochore [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    TACC/TOG complex [IDALink to PubMed article]
    Biological Process: mitotic cell cycle spindle assembly checkpoint [NASLink to PubMed article]
    spindle assembly [TASLink to PubMed article]
    attachment of spindle microtubules to kinetochore [IDALink to PubMed article]
    establishment or maintenance of cell polarity [IMPLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    cytoplasmic microtubule organization [IMPLink to PubMed article]
    microtubule cytoskeleton organization [IMPLink to PubMed article]
    microtubule-based process [ICLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    microtubule binding [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQDQEEDYS KLPLESRIVH KVWKVRLSAY EECSKSFSLS ADGSDNCFEL WNNQSELWKS  60
   61 VLTDSNVAAQ EAGTAAFVAY CRFSDPSHLL KAREISVLSI SEKCLTSPRA GTRENALEAL 120
  121 MLLVEADSAA PVIESIIPSL SARSPKVIAS NVAAIASLVE QFGAKVIPSK MIIPHISNLF 180
  181 GHADKNVRKE ASRLTVNIYR WTGDPLKDLL FKDLRPVQTK ELESLFAELP TEPPKQTRFL 240
  241 KSQQPTSEPN VETQVEEQPA LENEESEPEP SDDQFDLVEE VDVLPNVDPN LETLMASSKW 300
  301 KDRKEALDKL LPVLSQPKIK DNDFFNLVAI LTKSVSKDAN IMVVINAAHC IQAMAKGLRS 360
  361 NFSKYASTSI NALLERSKEK KANVIESLSS AMDAVLATSS LDDLAELIAS FAGNKNPQIK 420
  421 SSCFSLFSRS FSNMTSLPSK FTVDTCAKAC VPGVSDTFEP VRSAAAEALG VLMKLVGERA 480
  481 INQYLSPLDD IRKSKIRSFY ETATVKAKAP TKKSKVKPSK QEESKVVVPS NAKAVKKSVV 540
  541 PSSPVVPSPR KATNKSLSMD VSKGNAFENG PLLPRPTTRP VSRGLSRGTS SSLQQKVKAS 600
  601 TPLNSGALNE TVQNLKNMEL DDPAPQPAKH SRVDRYEHPK VLEDNDSTIS SLESLKRENE 660
  661 ELREQLKVEH EENISMQKQL SELKGELNTL RSARKASPIG DRKPAFMRRA NTDFLELSTS 720
  721 PSFQRSVREF EPTRPKLYSS IDVNQRSPLA SAKTNGNFTF HAELPRSPFS SRANNINPDW 780
  781 TKAIDLAAKL KQKITEMKQT DQRHQGLIH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..489] PSI-BLAST 71.39794 Karyopherin beta2
    2 View Details [490..640] deduced N/A No confident structure predictions are available.
    3 View Details [641..809] MSA 4.246996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  3.05338750264476 bayes_pls_golite062009
  • binding
    		•  2.6374633159018 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.61566088685247 bayes_pls_golite062009
  • actin binding
    		•  1.76244772281676 bayes_pls_golite062009
  • protein binding
    		•  1.73688475473996 bayes_pls_golite062009
  • transporter activity
    		•  1.55621630624352 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.33334123659384 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  1.15447282085461 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.350388174853674 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.345785895390889 bayes_pls_golite062009
  • signal sequence binding
    		•  0.27824906981293 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.141331164449492 bayes_pls_golite062009
  • RNA binding
    		•  0.0287526191298597 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle