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Protein Overview: Hlc-PA, FBpp0310396

General Information:
Name(s) found: FBpp0310396 [FlyBase]
Hlc-PA / FBpp0076917 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • type=protein; loc=X:complement(21256883..21257318,21257377..21257805,21258001..21258752,21258813..21258878); ID=FBpp0310396; name=Hlc-PB; parent=FBgn0001565,FBtr0343853; dbxref=FlyBase:FBpp0310396,FlyBase_Annotation_IDs:CG1666-PB; MD5=4746b26ab5b49eed10f2af61c2233b44; length=560; release=r5.56; species=Dmel; [FlyBase]
  • The gene Helicase is referred to in FlyBase by the symbol Dmel\Hlc (CG1666, FBgn0001565). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:21256542..21258967. It has the cytological map location 20A1. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent RNA helicase activity. The biological processes in which it is involved are not known. 20 alleles are reported. The phenotypes of these alleles are annotated with: central nervous system; peripheral nervous system. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 560 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: nucleic acid binding [IEA]
    ATP binding [IEA]
    ATP-dependent RNA helicase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQMTQKTVQ FHELELDQRI LKAVAQLGWQ QPTLIQSTAI PLLLEGKDVV VRARTGSGKT  60
   61 ATYALPLIQK ILNSKLNASE QYVSAVVLAP TKELCRQSRK VIEQLVESCG KVVRVADIAD 120
  121 SSNDTVTQRH ALSESPDIVV ATPANLLAYA EAGSVVDLKH VETLVVDEAD LVFAYGYEKD 180
  181 FKRLIKHLPP IYQAVLVSAT LTDDVVRMKG LCLNNPVTLK LEEPELVPQD QLSHQRILAE 240
  241 ENDKPAILYA LLKLRLIRGK SIIFVNSIDR CYKVRLFLEQ FGIRACVLNS ELPANIRIHT 300
  301 ISQFNKGTYD IIIASDEHHM EKPGGKSATN RKSPRSGDME SSASRGIDFQ CVNNVINFDF 360
  361 PRDVTSYIHR AGRTARGNNK GSVLSFVSMK ESKVNDSVEK KLCDSFAAQE GEQIIKNYQF 420
  421 KMEEVESFRY RAQDCWRAAT RVAVHDTRIR EIKIEILNCE KLKAFFEENK RDLQALRHDK 480
  481 PLRAIKVQSH LSDMPEYIVP KALKRVVGTS SSPVGASEAK QPRQSAAKAA FERQVNDPLM 540
  541 ASQVDFGKRR PAHRRKKKAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..405] PSI-BLAST 86.69897 No description for 2db3A was found.
    2 View Details [406..478] PSI-BLAST 14.522879 Nucleotide excision repair enzyme UvrB
    3 View Details [479..560] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle