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Protein Overview: CG1753-PA, CG175...

General Information:
Name(s) found: FBpp0309380 [FlyBase]
CG1753-PB / FBpp0076938 [FlyBase]
CG1753-PA / FBpp0076937 [FlyBase]
Description(s) found:
Found 40 descriptions.
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  • type=protein; loc=X:join(20918217..20918439,20918584..20919625,20919692..20919995); ID=FBpp0309380; name=Cbs-PC; parent=FBgn0031148,FBtr0340437; dbxref=FlyBase:FBpp0309380,FlyBase_Annotation_IDs:CG1753-PC; MD5=7b56b933cbb8de9931d6c084f9a6be05; length=522; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG1753 (CG1753, FBgn0031148). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:20916165..20920127. It has the cytological map location 19E7. Based on sequence similarity, it is predicted to have molecular function</span>: cystathionine beta-synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cysteine biosynthetic process via cystathionine; cysteine biosynthetic process from serine. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG1753 (CG1753, FBgn0031148). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:20916165..20920127. It has the cytological map location 19E7. Based on sequence similarity, it is predicted to have molecular function</span>: cystathionine beta-synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cysteine biosynthetic process via cystathionine; cysteine biosynthetic process from serine. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 522 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: cysteine biosynthetic process via cystathionine [IEA]
    cysteine biosynthetic process from serine [IEA]
    Molecular Function: pyridoxal phosphate binding [IEA]
    cystathionine beta-synthase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQPKPYERP ADFIDPGKPS KCKWHLGTAE KSPHIHRGIA HRQQITPNIL EVIGCTPLVK  60
   61 LNNIPASDGI ECEMYAKCEF LNPGGSVKDR IGYRMVQDAE EQGLLKPGYT IIEPTSGNTG 120
  121 IGLAMACAVK GYKCIIVMPE KMSNEKVSAL RTLGAKIIRT PTEAAYDSPE GLIYVAQQLQ 180
  181 RETPNSIVLD QYRNAGNPLA HYDGTAAEIL WQLDNKVDMI VVSAGTAGTI SGIGRKIKEQ 240
  241 VPSCQIVGVD PYGSILARPA ELNKTDVQFY EVEGIGYDFP PTVFDDTVVD VWTKIGDSDC 300
  301 FPMSRRLNAE EGLLCGGSSG GAMHAALEHA RKLKKGQRCV VILPDGIRNY MTKFVSDNWM 360
  361 EARNFKEPVN EHGHWWWSLA IAELELPAPP VILKSDATVG EAIALMKKHR VDQLPVVDQD 420
  421 DGSVLGVVGQ ETLITQIVSM NRQQSDPAIK ALNKRVIRLN ESEILGKLAR VLEVDPSVLI 480
  481 LGKNPAGKVE LKALATKLDV TTFIAAGKQK PKANGTTNGG SH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..370] PSI-BLAST 87.69897 Cystathionine beta-synthase
    2 View Details [371..522] PSI-BLAST 12.30103 No description for 2v8qE was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cysteine synthase activity
    		•  5.18562032111987 bayes_pls_golite062009
  • cystathionine beta-synthase activity
    		•  2.46824200933572 bayes_pls_golite062009
  • catalytic activity
    		•  2.38994231321972 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.04832999357666 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • binding
    		•  0.791501201936306 bayes_pls_golite062009
  • threonine synthase activity
    		•  0.727838845253199 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  0.37325071016009 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  1.03812086384118 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.683927541769979 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.333489822810031 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.240245563840066 bayes_pls_golite062009
  • catalytic activity
    		•  0.181756622780318 bayes_pls_golite062009
  • protein binding
    		•  0.069261088689358 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle