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Protein Overview: amn-PA

General Information:
Name(s) found: amn-PA / FBpp0074571 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene amnesiac is referred to in FlyBase by the symbol Dmel\amn (CG11937, FBgn0086782). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19780141..19784093. It has the cytological map location 18F4-19A2. Based on sequence similarity, it is predicted to have molecular function</span>: neuropeptide hormone activity. There is experimental evidence that it is involved in the biological process</span>: olfactory learning; perineurial glial growth; learning or memory; memory; antimicrobial humoral response; behavioral response to ethanol. 84 alleles are reported. The phenotypes of these alleles are annotated with: calyx of mushroom body; eye; central nervous system; surface associated glial cell; embryonic/larval heart; bouton; Kenyon cell; intersegmental nerve; wing vein. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 180 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cAMP biosynthetic process [TAS]
    perineurial glial growth [IMP]
    regulation of heart contraction [NAS]
    male courtship behavior [TAS]
    olfactory learning [IDA][TAS]
    behavioral response to ethanol [IMP][NAS]
    [NOT]learning [TAS]
    memory [IMP][TAS]
    learning or memory [IDA][IMP][NAS]
    long-term memory [TAS]
    neuropeptide signaling pathway [TAS]
    anesthesia-resistant memory [TAS]
    courtship behavior [TAS]
    antimicrobial humoral response [IMP]
    activation of adenylate cyclase activity [TAS]
    cAMP-mediated signaling [NAS][TAS]
    Molecular Function: G-protein-coupled receptor binding [NAS]
    neuropeptide hormone activity [ISS][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSFCCCFYP AAVALHCVLL FYTFFLLFRA SALRRRVVSG SKGSAALALC RQFEQLSASR  60
   61 RERAEECRTT QLRYHYHRNG AQSRSLCAAV LCCKRSYIPR PNFSCFSLVF PVGQRFAAAR 120
  121 TRFGPTLVAS WPLCNDSETK VLTKWPSCSL IGRRSVPRGQ PKFSRENPRA LSPSLLGEMR 180
  181

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..180] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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