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Protein Overview: Bap-PA

General Information:
Name(s) found: Bap-PA / FBpp0074558 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene Ã?&#142;Ã?&#146; Adaptin is referred to in FlyBase by the symbol Dmel\Bap (CG12532, FBgn0010380). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19625036..19628620. It has the cytological map location 18E4-18E5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; protein transporter activity. It is reported to be involved in the biological process</span>: vesicle coating; neurotransmitter secretion; synaptic vesicle coating. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 921 amino acids

    Gene Ontology:
    Cellular Component: synaptic vesicle [TAS]
    AP-1 adaptor complex [ISS][NAS]
    coated vesicle [TAS]
    plasma membrane [IDA]
    Biological Process: vesicle coating [TAS]
    vesicle-mediated transport [IEA]
    synaptic vesicle coating [TAS]
    intracellular protein transport [IEA]
    neurotransmitter secretion [NAS]
    Molecular Function: protein binding [IEA]
    protein transporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDSKYFTTT KKGEIFELKS ELNNDKKEKK KEAVKKVIAS MTVGKDVSAL FPDVVNCMQT  60
   61 DNLELKKLVY LYLMNYAKSQ PDMAIMAVNT FVKDCEDSNP LIRALAVRTM GCIRVDKITE 120
  121 YLCEPLRKCL KDEDPYVRKT AAVCVAKLYD ISATMVEDQG FLDQLKDLLS DSNPMVVANA 180
  181 VAALSEINEA SQSGQPLVEM NSVTINKLLT ALNECTEWGQ VFILDSLANY SPKDEREAQS 240
  241 ICERITPRLA HANAAVVLSA VKVLMKLLEM LSSDSDFCAT LTKKLAPPLV TLLSSEPEVQ 300
  301 YVALRNINLI VQKRPDILKH EMKVFFVKYN DPIYVKLEKL DIMIRLANQS NIAQVLSELK 360
  361 EYATEVDVDF VRKAVRAIGR CAIKVEPSAE RCVSTLLDLI QTKVNYVVQE AIVVIKDIFR 420
  421 KYPNKYESII STLCENLDTL DEPEARASMV WIIGEYAERI DNADELLDSF LEGFQDENAQ 480
  481 VQLQLLTAVV KLFLKRPSDT QELVQHVLSL ATQDSDNPDL RDRGFIYWRL LSTDPAAAKE 540
  541 VVLADKPLIS EETDLLEPTL LDELICHISS LASVYHKPPT AFVEGRGAGV RKSLPNRAAG 600
  601 SAAGAEQAEN AAGSEAMVIP NQESLIGDLL SMDINAPAMP SAPAATSNVD LLGGGLDILL 660
  661 GGPPAEAAPG GATSLLGDIF GLGGATLSVG VQIPKVTWLP AEKGKGLEIQ GTFSRRNGEV 720
  721 FMDMTLTNKA MQPMTNFAIQ LNKNSFGLVP ASPMQAAPLP PNQSIEVSMA LGTNGPIQRM 780
  781 EPLNNLQVAV KNNIDIFYFA CLVHGNVLFA EDGQLDKRVF LNTWKEIPAA NELQYTLSGV 840
  841 IGTTDGIASK MTTNNIFTIA KRNVEGQDML YQSLKLTNNI WVLLELKLQP GNPEATLSLK 900
  901 SRSVEVANII FAAYEAIIRS P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..595] PSI-BLAST 116.0 AP1 clathrin adaptor core
    2 View Details [596..676] deduced N/A No confident structure predictions are available.
    3 View Details [677..921] PSI-BLAST 55.30103 Beta2-adaptin AP2 ear domain, N-terminal subdomain; Beta2-adaptin AP2, C-terminal subdomain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle