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Protein Overview: Tyler-PB

General Information:
Name(s) found: Tyler-PB / FBpp0074505 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene Tyler is referred to in FlyBase by the symbol Dmel\Tyler (CG14208, FBgn0031038). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19505559..19509647. It has the cytological map location 18D3. Based on sequence similarity, it is predicted to have molecular function</span>: transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transport. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 441 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    mitochondrial envelope [ISS]
    Biological Process: transmembrane transport [IEA]
    transport [ISS]
    Molecular Function: transmembrane transporter activity [ISS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPQLMSQME NGGEEEGCRL ECKEMDPLRL TTLILSADPR YRIKPMQQVV SALVGGLITT  60
   61 FVVTPLEVVK TRVQTQHAIR QRPTVSKLCY VYHNGLMTHV CRSSDICVPK PGRDPQNLRP 120
  121 LRGAMDAFVK IVCTSGFSGL WAGLSPTLVS ALPSTIIYFL TYEYIKNSLS HIYLVSQKFE 180
  181 ESGMKDQVPG ADGGDPLDQA TRGINVSATA PVSTASLPYY VPMASGICSR TIVVTAITPI 240
  241 EMVRIKMQSE YMTYAELWRV LRSLIRQHGI LGLWRGWPPT VMRDAPFSGT YWAVYEAIKR 300
  301 AFSVTEPTFL FSFLTGAISG AVATFVTMPF DLITTHTQIE LGQDVLYEEI GAGTGAGTGT 360
  361 GAGARPKTPQ SAVANSRPSV LSRMRQIYRL QGVRGLYVGV MPRMLRVVPA CAIMISTFEY 420
  421 SKSFFFHYNL DLQEAAYRRS Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..441] PSI-BLAST 62.09691 structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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