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Protein Overview: Aats-his-PA

General Information:
Name(s) found: Aats-his-PA / FBpp0074365 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Histidyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-his (CG6335, FBgn0027087). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:18409432..18414480. It has the cytological map location 17C1. Based on sequence similarity, it is predicted to have molecular function</span>: histidine-tRNA ligase activity. It is reported to be involved in the biological process</span>: histidyl-tRNA aminoacylation. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 522 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: histidyl-tRNA aminoacylation [IEA][NAS]
    Molecular Function: histidine-tRNA ligase activity [ISS][NAS]
    ATP binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDTREQILE QIKVQGDLVR QLKAAKESKE KIDEEVARLL ALKATLGGDA APTNQKFTLK  60
   61 TPKGTRDYGP QQMTLRQGVL DKIVQVFKRH GGEAIDTPVF ELKEVLTGKY GEDSKLIYDL 120
  121 KDQGGEILSM RYDLTVPLAR YLAMNKISSI KRYHIAKVYR RDNPAMTKGR YREFYQCDFD 180
  181 IAGTYDPMLP DAECVKIVSE ILDTLDIGDY VIKLNHRQLL DGMFQACGVP ADSFRTICSA 240
  241 VDKLDKSPWA DVRKEMVDEK GLDEAAADRI GEYVRLSGGA ELVEQLLANE KLKAVPNAVK 300
  301 GLEGMKQLLK YCSIFGLDKR VSFDLSLARG LDYYTGVIYE GVLKGESATV ASPAKTSQQN 360
  361 GEQANEPATV GSVAGGGRYD NLVGMFDPRG KAVPCVGVSI GVERIFSVLE ARAAASGLKL 420
  421 RTSDVEVYVA SAHKGLHEQR LKVLNLLWDA GVKAEHSYKL NPKLLVQLQH CEEHQIPLVV 480
  481 VLGDAELAQG LVKLREVTTR EETNVKLEDL AAEIRRRQQA SA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] FFAS03 2.28 No description for 2azxA was found.
    2 View Details [69..522] PSI-BLAST 82.39794 Histidyl-tRNA synthetase (HisRS), C-terminal domain; Histidyl-tRNA synthetase (HisRS)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle