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Protein Overview: Dhc16F-PA

General Information:
Name(s) found: Dhc16F-PA / FBpp0074283 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Dynein heavy chain at 16F is referred to in FlyBase by the symbol Dmel\Dhc16F (CG7092, FBgn0013809). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17958635..17972505. It has the cytological map location 16F6. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; motor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: microtubule-based movement. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 4081 amino acids

    Gene Ontology:
    Cellular Component: axonemal dynein complex [ISS]
    microtubule associated complex [ISS]
    Biological Process: regulation of transcription, DNA-dependent [IEA]
    microtubule-based movement [IEA][ISS]
    Molecular Function: ATPase activity [IEA]
    ATP binding [IEA]
    microtubule motor activity [IEA]
    transcription factor binding [IEA]
    motor activity [ISS]
    ATPase activity, coupled [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGMNRHLIS KGKDRSKIKI KGKEKEKERK KDEDDDGSRK ARERGRSRRQ SAGGGDHSVD  60
   61 MGFKRVTGED RPSSMSMDRL DSDFAAFTDR ASDANDGSIT GPADGNGKKA QTGGKQKRAS 120
  121 KHRLNFSTSK SAGSGTGNKS RSASTTKITT GASLIPDLNL IINRMRNMPD DSFVYMDYML 180
  181 PHDSEYFTPY SLREVEYKDL NTYEPFYTVT RHGVTFWHCS ENFFTPLDQW QQEFKQFLSI 240
  241 IQIRSFSIFR LWKGFKVWEK TIKWRKLNEA RDYLQNNLFI VIPQLAKAIL RMRSDIVQLQ 300
  301 RLNFVNVSNI ENWHPFYFLE THMRIYEQLH KTFTDFREFI AKTIFRACTD AIQARGFYPD 360
  361 DEVNYYPSLK KMREAHSFMD RARKRAFCKT LTNFLTYCDM MVYQMLYRIT KKSFEDLATS 420
  421 FEVHDEVGPS EADINKHDRV DKRIEKQRPQ DKPQSPFFLA MLRLLPDRID IEPSEDIIRI 480
  481 IFQRITGLIL ETVLEIHPFT TDPFFTQYTQ PSIMGRQEEV LYEGAPDLHY LLRADIRFQY 540
  541 NRKNMFVLIR KAYERARLYT QRFHQIRENF EIDNSTDPTV LNTERDLQIL RAYCDRYCNN 600
  601 VRALDGILEY VFLGLLKLTQ TNFKDTVTPV CSRLQNVLAT YLPKLAEEET TRLYEEAQDF 660
  661 HGRICYEPHE TLEIVAHIRF LDKCSTELDG IFDGIDYVHD LLLIIKDFGI PIDDDSKEDY 720
  721 MDTEDYLNRT RETLEEIREK RQDFINRLED AMQDDIAALK EDIHEVAIEA LQPWLLDANS 780
  781 NRLSVTNKLD SMLERLNKCR ETADEFLGYQ KEFQIDLTMY DEMASGFYDI RMRQNLYRTW 840
  841 SDWEESLAEW IVSDFNTLNV VDMVELNSKT IKNCMQFQKY LPENNIVPVL QKSAEAFKEK 900
  901 LPVIGYLRNP NLRARHWAEI EDLLNRKFFQ EKDILIQTYE DVHAFDDVAI GEALMQISSQ 960
  961 ATGEVQLENM LKGIETTWKE TELSIVPHHD AKDVFILAGT EELQAVLDDS NVNINTIAAS1020
 1021 KFVGPIKSKV DEWINAMDQF AKTFESWMDC QGAWIYLEAI FASADIQRQL PHEAKMFFTV1080
 1081 DKSFKETVRQ AKKVALALPT MSSVDVHKVL VENNRLLDLI SRGLEAYLEV KRVVFPRFYF1140
 1141 LSNDELLEIL AQTRIPQAVQ PHLRKCFDAI YRLEFGSKEG GDGKMVATND IVAFLSPEGE1200
 1201 KLQFGKGLKA RGAVEEWLSK VEEAMFVSCK RYMRFGYQCY PAKEREDWFQ DHPNQVVLTV1260
 1261 SQVQWAADIH RIYEGKERNP LNILEKMAKF EIKCLKDLGA LAALTRKNIS SLLRKILCAL1320
 1321 ITIDVHAKDS VRMLIEKEVC KASDFNWLKM LRFYWADETE TVYSRMAAAN IPYYYEYLGA1380
 1381 GGVLVLTPLT DRCYLCLMGA FQMDLGGAPA GPAGTGKTET TKDLAKALAK QCVVFNCSDG1440
 1441 LDYKMMGRFF SGLAQCGAWC CFDEFNRIDI EVLSVIAQQL ITIRTAKAMR VKRFIFEGRE1500
 1501 IKINRSCCVF ITMNPGYAGR TELPDNLKAL FRPISMMVPD YALISEVILY SEGFEDPKIL1560
 1561 ARKMVQMYQL CSQQLSQQNH YDFGMRAVKS VLVMAGALKR ASPNQREDIT LIAALRDSNI1620
 1621 PKFLADDAVL FRGILSDLFP GVELPDSQHP HLEASLRLGL RQKNLQAVPT TIRKCLQLYE1680
 1681 TMCVRWGVML VGPTGGGKSV VLHALEFALS HLFENEVQDP NFRPVVIQTM NPKAVTMNEL1740
 1741 YGYVDLKTLE WQDGLLGLAV RTATTVEDEI HQWIMCDGPV DAVWIENLNT VLDDNKMLCL1800
 1801 ANSERIKLTA WIHMLFEVQD LLQASPATVS RCGMVYVDPG DLGWIPLIDT WREVDMKHKL1860
 1861 PAPLAEFCYQ LFVGYFDKAL KIERKRAVYT IHQVLGSKVR LCCELNSAQF EAVKWSAMSE1920
 1921 EQGKELVTKI FAWAVLWAIA SNLKDAEKVS FEEQWSKAIA QHPNMTLPNF TLWNYRIDLE1980
 1981 KMDWGSWIDI MAKFVFDPET SYYDMQVPTV DTTKYGYVSD LLFKRGMPVM VTGDTGVGKT2040
 2041 VLAISCMKRL SQGNVIPVIL NFSAQTSSNR TQEMIEGPLE KRKKTQLGAP VGKTVIVFID2100
 2101 DVNMPKLDTY GASPAIELLR QFLDFKGFYD REKLYWKEIL DVVLGCACAP PGGGRNPLTP2160
 2161 RFVRHFALFS LPKPNEETLT QIFNGILRGF LQTFSSAVRA LSEPMVNACV DVYMRVATVM2220
 2221 LPTPDKSHYI FNLRDLSKCI QGILQASNLH YNQENQILRL FYHETTRVFH DRLINIEDKN2280
 2281 IFKALMKEVC MDHFNRPVIN DNEPPILFGD FMVFGKPKNE RIYDEIRDHT KLESVLNDYI2340
 2341 ADYNSVAVGK QMKLILFQDA MEHTVRLARL LRSDRGNGLL VGVAGMGKQS LTRLASHVNE2400
 2401 YNCWQIEMRR NYDLNAFHED LRVLYRIAGI DNQPVTFLLI DSQIVEEEFL EDINNILNSG2460
 2461 EVPNLFEGDE FEKIILDARD GCNENRKDDP CTRDDIYKFF INRVRNNLHV VMSMSPVGDA2520
 2521 FRRRCRMFPS LVNCTTIDWF TSWPTEALYS VALGLLTKIA PKMEDRISLA STTVFMHKTV2580
 2581 EDASVKFYKE MKRHYYTTPS SYLELLKLYQ NLLKIKNMEI IAKRKRIANG LNKLLETNEV2640
 2641 IAVMGKELEV MVPQLDEKSA MMKSLVDNLT KETKQADAVK QSVLEDEMNA KEKAAVAQAI2700
 2701 SEDAGKDLEI AMPALREAEE ALKGLTKADI NELKSFTTPP ALVQFCMEAV CILLGVKPTW2760
 2761 ASAKAIMADI NFIKRLFEYD KEHMKEDTLK KVKKYIDHKD FVPAKFEKVS KVAKSMSMWV2820
 2821 ISMDKFSKVY KVVEPKIKRK EAAEAELKEV MTVLRQKQKE LAAVEAKIQG LRDSLEEKQR2880
 2881 EFQVIQDNVD LTYGRINRAG RLTSALSDEQ VRWRETVKSL TGDLACVPGD VLVAAACVAY2940
 2941 LGAFSHEYRR DMSALWVSKC REHKIPSSPE FNLLKVLGDP YEMRQWNVDG LPKDNISIEN3000
 3001 GIYATRALRW ALMIDPQEQA NRWIRNMERA NNLQVIKMTD STMMRVLENA VRQGYPVLLE3060
 3061 EINETIDPSL RPILQRETYR FEGRTYLKLG DMVIDYDDNF KLYMTTKLPN PHYLPEVCIN3120
 3121 VTLVNFLVTE SGLEDQLLAD IVAIELPAME IQRNDLVVKI NSDKQQLLAL EDKVLKLLFN3180
 3181 SEGNILDDEE LVETLNDAKE TSLIIAARLI DTEETEKVIT ASRERYRILA SRGAILYFVV3240
 3241 AGLAEIDPMY QYSLKYFTQV FCNVLRLDHP PQSVEVRIST LMTDELRAIF DNISRGLFEN3300
 3301 HKIIFSFLLA LSVERQEGRV TEEEFLFLSR GPVGNIRTKI QPAKIKMSQI EWDSCIFLED3360
 3361 NFSSFFSGLT DELDKPFFIQ MQENKEVFDF AQTNQPPTDK WNKRLRVFHK LMFISAFRKP3420
 3421 RFLLNVVCYL QSTVGKYFTE ASGGTQLSSV YLDTSAVTPL IFVLSTGSDP MSGFLKFTTQ3480
 3481 MQFTDKYYSI SLGQGQGPLA ENLIEKSLRL GHWVFLQNCH LATSFMQTLE TIVRNLTLGI3540
 3541 TKAHVDFRLY LSSMPIQTFP ISVLQNSVKI TNEPPKGIKA NVFGALTDLK QDFFEQHIQN3600
 3601 GNWRAIVFGL CMFHAVLLER RKFGPLGWNI TYEFSESDRE CGLKTLDFFI DREVLDEIPW3660
 3661 EAILYINGDI TWGGRVTDYW DLRCLRTILT IFSSKRIIQP DYKYCRGDSY YRDPRKKTLT3720
 3721 EYSAYVQGFP VLEDPEIFGM NQNANIVFQT KETAFFINTL LLGQPRSAAD EGQAMENEIA3780
 3781 QQTIARIQKA LATKIKREPI HDTLSVLDAK GQVPSLTIVL VQEIDRFNIA LGIIHDSLVN3840
 3841 LSKAIKGLVV MSEELENVFK ALLSNQVPAS WAKRSFLSIK PLPSYISDFQ RRIDFIQQWA3900
 3901 ENGAPRSYWI SGFFFPQSFL TGVLQTYARR RVLPIDSLKI DFDVFERELV QQDFFEMHTN3960
 3961 NMSDQKLYGN LPECTDAIIN VHGIFIEAAR WDLSKGGLCD ANFGELFSRM PVVRFKPCLE4020
 4021 ISPTVRYEAP LYKTQQRSGV LSTTGHSTNF ILAVLLRSHN DPEFWIMRGT ALVSAVLENI4080
 4081 C

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle