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Protein Overview: CG5703-PA, FBpp0...

General Information:
Name(s) found: FBpp0309486 [FlyBase]
CG5703-PA / FBpp0074226 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=X:join(17526455..17526493,17526623..17527141,17527296..17527466); ID=FBpp0309486; name=CG5703-PB; parent=FBgn0030853,FBtr0340622; dbxref=FlyBase:FBpp0309486,FlyBase_Annotation_IDs:CG5703-PB; MD5=a97c0f46d7df3ec2f1215240790dedab; length=242; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG5703 (CG5703, FBgn0030853). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17526122..17527539. It has the cytological map location 16B10. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 242 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex I [ISS]
    Biological Process: mitochondrial electron transport, NADH to ubiquinone [ISS]
    Molecular Function: NADH dehydrogenase activity [ISS]
    NAD or NADH binding [IEA]
    NADH dehydrogenase (ubiquinone) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTNCASKTL AAVRANIRAI ATSSARASDN LFVHRDTPED NPNIPFEFTA ENKKRVEAIL  60
   61 SIYPEGHKRG AMIPLLDLAQ RQYGWLPISA MHKVAEILQL PNMRVYEVAT FYTMFMRKPT 120
  121 GKYHIQVCTT TPCWLRGSDD ILETCKKQLG IGVGDTTKDR KFTISEVECL GACVNAPMVA 180
  181 INDDYYEDLT SKDMQDILND LKADKISPPG PRNGRFASEP KGEPTSLSEE PKGPGFGLQA 240
  241 GL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..242] PSI-BLAST 49.69897 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  9.90105969982332 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  8.92078442660684 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  8.81403581008074 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  8.78237088091479 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  8.15019987387908 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.56566449113494 bayes_pls_golite062009
  • electron carrier activity
    		•  1.9747415675561 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  0.64327334394445 bayes_pls_golite062009
  • glutathione transferase activity
    		•  0.441941661513454 bayes_pls_golite062009
  • binding
    		•  0.39192669546254 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  0.36869630503451 bayes_pls_golite062009
  • protein binding
    		•  0.157273259994554 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle