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Protein Overview: FBpp0293027

General Information:
Name(s) found: FBpp0293027 [FlyBase]
Description(s) found:
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  • gi|28571234|ref|NP_788919.1| forked, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|28381638|gb|AAO41690.1| forked, isoform C [Drosophila melanogaster] [NCBI NR]
  • type=protein; loc=X:join(17162595..17163022,17163964..17164147,17165255..17165437,17165521..17166738,17166925..17167381,17167545..17167865,17171648..17172176,17172984..17173344,17173452..17173700,17173766..17173974,17174043..17174433); ID=FBpp0293027; name=f-PC; parent=FBgn0262111,FBtr0304065; dbxref=FlyBase:FBpp0293027,FlyBase:FBpp0074197,FlyBase_Annotation_IDs:CG5424-PC,FlyBase_Annotation_IDs:CG42864-PC,REFSEQ:NP_788919,GB_protein:AAO41690,FlyMine:FBpp0293027,modMine:FBpp0293027; MD5=0e1448c55c2b34896c38756d52816fa2; length=1509; release=r5.56; species=Dmel; [FlyBase]
  • The gene forked is referred to in FlyBase by the symbol Dmel\f (CG5424, FBgn0000630). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:17146178..17174997. It has the cytological map location 15F4-15F7. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: actin filament bundle formation; cuticle pattern formation; antennal morphogenesis; bristle morphogenesis; epidermal cell differentiation; imaginal disc-derived wing hair organization. 95 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; peripheral nervous system; adult segment; cuticle; nervous system; thoracic segment; adult mesothoracic segment; cuticular specialization; wing hair; antennal segment; mesothoracic dorsal trichome. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • >CG5424-PC translation from_gene[CG5424 f FBgn0000630] seq_release:3 mol_weight=163912 cds_boundaries:(X:16,999,521..17,011,356[+]) aa_length:1509 transcript_info:[CG5424-RC seq_release:3] gene_info:[gene symbol:f FBgn0000630 gene_boundaries:(X:16,983, [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q86B49) CG5424-PC [DrosMelano7227.FASTAC.txt]
  • CG5424-PC, isoform C [Drosophila melanogaster]gi|28571234|ref|NP_788919.1| CG5424-PC [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(17162595..17163022,17163964..17164147,17165255..17165437,17165521..17166738,17166925..17167381,17167545..17167865,17171648..17172176,17172984..17173344,17173452..17173700,17173766..17173974,17174043..17174433); ID=FBpp0074197; nam [fly-100309-contam.fasta]
  • forked CG5424-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG5424-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(17162595..17163022,17163964..17164147,17165255..17165437,17165521..17166738,17166925..17167381,17167545..17167865,17171648..17172176,17172984..17173344,17173452..17173700,17173766..17173974,17174043..17174433); ID=FBpp0074197; name=f-PC; parent=FBgn0000630,FBtr0074423; dbxref=FlyBase:FBpp0074197,FlyBase_Annotation_IDs:CG5424-PC,GB_protein:AAO41690.1,REFSEQ:NP_788919,GB_protein:AAO41690; MD5=0e1448c55c2b34896c38756d52816fa2; length=1509; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(17162595..17163022,17163964..17164147,17165255..17165437,17165521..17166738,17166925..17167381,17167545..17167865,17171648..17172176,17172984..17173344,17173452..17173700,17173766..17173974,17174043..17174433); ID=FBpp0074197; name=f-PC; parent=FBgn0000630,FBtr0074423; dbxref=FlyBase:FBpp0074197,FlyBase_Annotation_IDs:CG5424-PC,GB_protein:AAO41690.1,REFSEQ:NP_788919,GB_protein:AAO41690; MD5=0e1448c55c2b34896c38756d52816fa2; length=1509; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Forked, isoform C OS=Drosophila melanogaster GN=f PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:join(17162595..17163022,17163964..17164147,17165255..17165437,17165521..17166738,17166925..17167381,17167545..17167865,17171648..17172176,17172984..17173344,17173452..17173700,17173766..17173974,17174043..17174433); ID=FBpp0293027; name=f-PC; parent=FBgn0262111,FBtr0304065; dbxref=FlyBase:FBpp0293027,FlyBase:FBpp0074197,FlyBase_Annotation_IDs:CG5424-PC,FlyBase_Annotation_IDs:CG42864-PC,REFSEQ:NP_788919,GB_protein:AAO41690,FlyMine:FBpp0293027,modMine:FBpp0293027; MD5=0e1448c55c2b34896c38756d52816fa2; length=1509; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(17268562..17268989,17269931..17270114,17271222..17271404,17271488..17272705,17272892..17273348,17273512..17273832,17277615..17278143,17278951..17279311,17279419..17279667,17279733..17279941,17280010..17280400); ID=FBpp0293027; name=f-PC; parent=FBgn0262111,FBtr0304065; dbxref=FlyBase:FBpp0293027,FlyBase:FBpp0074197,FlyBase_Annotation_IDs:CG5424-PC,FlyBase_Annotation_IDs:CG42864-PC,REFSEQ:NP_788919,GB_protein:AAO41690,FlyMine:FBpp0293027,modMine:FBpp0293027; MD5=0e1448c55c2b34896c38756d52816fa2; length=1509; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(17268562..17268989,17269931..17270114,17271222..17271404,17271488..17272705,17272892..17273348,17273512..17273832,17277615..17278143,17278951..17279311,17279419..17279667,17279733..17279941,17280010..17280400); ID=FBpp0293027; name=f-PC; parent=FBgn0262111,FBtr0304065; dbxref=FlyBase:FBpp0293027,FlyBase:FBpp0074197,FlyBase_Annotation_IDs:CG5424-PC,FlyBase_Annotation_IDs:CG42864-PC,REFSEQ:NP_788919,GB_protein:AAO41690,FlyMine:FBpp0293027,modMine:FBpp0293027; MD5=0e1448c55c2b34896c38756d52816fa2; length=1509; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q0KHR2, Forked, isoform C OS=Drosophila melanogaster GN=f PE=4 SV=1 [DROME.fasta.20160308]
  • FBpp0293027 type=protein; loc=X:join(17268562..17268989,17269931..17270114,17271222..17271404,17271488..17272705,17272892..17273348,17273512..17273832,17277615..17278143,17278951..17279311,17279419..17279667,17279733..17279941,17280010..17280400); ID=FBpp0293027; name=f-PC; parent=FBgn0262111,FBtr0304065; dbxref=FlyBase:FBpp0293027,FlyBase:FBpp0074197,FlyBase_Annotation_IDs:CG5424-PC,FlyBase_Annotation_IDs:CG42864-PC,REFSEQ:NP_788919,GB_protein:AAO41690,FlyMine:FBpp0293027,modMine:FBpp0293027; MD5=0e1448c55c2b34896c38756d52816fa2; length=1509; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:join(17268562..17268989,17269931..17270114,17271222..17271404,17271488..17272705,17272892..17273348,17273512..17273832,17277615..17278143,17278951..17279311,17279419..17279667,17279733..17279941,17280010..17280400); ID=FBpp0293027; name=f-PC; parent=FBgn0262111,FBtr0304065; dbxref=FlyBase:FBpp0293027,FlyBase:FBpp0074197,FlyBase_Annotation_IDs:CG5424-PC,FlyBase_Annotation_IDs:CG42864-PC,REFSEQ:NP_788919,GB_protein:AAO41690,UniProt/TrEMBL:Q86B49,FlyMine:FBpp0293027,modMine:FBpp0293027; MD5=0e1448c55c2b34896c38756d52816fa2; length=1509; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1509 amino acids

    Gene Ontology:
    Cellular Component: filamentous actin [IDA]
    Biological Process: bristle morphogenesis [IMP]
    epidermal cell differentiation [IMP]
    antennal morphogenesis [IMP]
    imaginal disc-derived wing hair organization [IMP]
    actin filament bundle assembly [IMP]
    cuticle pattern formation [IMP]
    Molecular Function: actin binding [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTSLTSYRR SKQKSKSNND IHTIIATEVV TAAILSSSVH SSSTGSEIGD GGQGNTSLIE  60
   61 EAAAQDQSSE EQDRQHQHAK DPLAQTEMNH HPHSHHQRKS AVEVVRQQMD DDGDQDSNDD 120
  121 DETMPMMSGV GRKEQNNRRS VVSANTQMDN DVTPVYLAAQ EGHLEVLKFL VLEAGGSLYV 180
  181 RARDGMAPIH AASQMGCLDC LKWMVQDQGV DPNLRDGDGA TPLHFAASRG HLSVVRWLLN 240
  241 HGAKLSLDKY GKSPINDAAE NQQVECLNVL VQHGTSVDYN GKSSSQRHKS QQQLHQQHQQ 300
  301 QQQQQQQQHL SSSCNSNSNS SKQTSRSNTI KSKSSSTLSS DVEPFYLHPP ALAGGSGGSG 360
  361 MGLGMGMGMG MGMSMGLGIS RKNSDALYSQ QSRSSSEKLY NGSSSLGGNP GGNSSSGGGG 420
  421 VGGGGGSGGA LLPNDGLYVN PMRNGGMYNT PSPNGSISGE SFFLHDPQDI IYNRVRDLFV 480
  481 DSDCSSSVKQ HGKSHAHQLL QSKAGNAMTI QADVHSSSSG AGSGSDESVS ISSSFNSPKQ 540
  541 QQQLRSQSFN RHGSSSNISA SGNIKNNNYK AHKGKPSNQN GGGDHDYEDI YLVREESRKQ 600
  601 HQQQQQHQLQ QQQQLQHQAT QQQQQQQQQQ QQLQHKYNVG RSRSRDSGSH SRSASASSTR 660
  661 STDIVLQYSN HHLNNKRNMN NNSNMNNSSS NIAQSSSSNN NNNSLLNRNK SHSIIGLHSS 720
  721 KYESSLKDNY SAKNVNLKNQ LLNGGIKSDT YESVCPPEDV AERTKQTHKN SMIRNNLADA 780
  781 SSNNNTSGSI NNISNIGNMN GGNQSSRNLK RVSSAPPMQN LAVVNGPPPP PLPPPLRAPV 840
  841 QQQRNNLSVD QPNSMTGNNG IYKKNVFGPN QGPTNANGTG GAAPPPVPAP NPVATEAVDS 900
  901 DSGLEVVEEP SLRPSELVRG NHNRTMSTIS ANKKAKLLNA GSTNGSSIAA SSDDSQSRYG 960
  961 GSVHAANGSA ANGHFYGYSE GNKNQGSNGN GNGNGNGGGG NYHSHPNQPH YATGQPHQYT1020
 1021 PSLYGGGSSA EDHYELTQQQ QQIYGETHLP SGQRTGGPNL VNKQLVLPFV PPSFPNKSQD1080
 1081 GVTHLIKPSE YLKSISIDKR SCPSSARSTD TEDYMQIQIA QQQSHPHQHQ HHPHPHPHPH1140
 1141 HPHQLHGMGE QPPLPPPPPP LPHGMLPPQP PMGPPMGVAG GQDATMSGKS HKPKKPHGSA1200
 1201 PNSQDTATRK QHQPLSAISI QDLNSVQLRR TDTQKVPKPY QMPARSLSMQ CLTSSTETYL1260
 1261 KSDLIAELKI SKDIPGIKKM KVEQQMASRM DSEHYMEITK QFSGNNYVDQ IYLQIPERDQ1320
 1321 AGNAIPDWKR QMMAKKAAER AKKDFEERMA QEAESRRLSQ IPQWKRDLLA RREETENKLK1380
 1381 AAIYTPKVEE NNRVADTWRL KNRAMSIDNI NINLAGMEQH YQQIQFQQKQ QQLQLGNKEN1440
 1441 HVDPKGADQD QEHGVGIGSG VGNANSGVIG GQELIDPSEG SQGRAEEEED NIIPWRAQLR1500
 1501 KTNSRLSLI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..426] PSI-BLAST 101.0 Ankyrin-R
    2 View Details [427..659] deduced N/A No confident structure predictions are available.
    3 View Details [660..819] deduced N/A No confident structure predictions are available.
    4 View Details [820..921] deduced N/A No confident structure predictions are available.
    5 View Details [922..993] deduced N/A No confident structure predictions are available.
    6 View Details [994..1241] MSA 2.105996 View MSA. No confident structure predictions are available.
    7 View Details [1242..1314] deduced N/A No confident structure predictions are available.
    8 View Details [1315..1411] MSA 1.015991 View MSA. No confident structure predictions are available.
    9 View Details [1412..1509] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  3.30812396303844 bayes_pls_golite062009
  • actin binding
    		•  3.15358758538214 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  2.4948065111495 bayes_pls_golite062009
  • binding
    		•  2.03195138036959 bayes_pls_golite062009
  • actin filament binding
    		•  1.8758804992293 bayes_pls_golite062009
  • protein binding
    		•  1.6716587413544 bayes_pls_golite062009
  • myosin binding
    		•  1.55894148251645 bayes_pls_golite062009
  • myosin phosphatase activity
    		•  0.991228379874891 bayes_pls_golite062009
  • structural constituent of muscle
    		•  0.304639267984357 bayes_pls_golite062009
  • structural molecule activity
    		•  0.242743465134414 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.30

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle