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View Structure Prediction Details

Protein: FBpp0293027
Organism: Drosophila melanogaster
Length: 1509 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0293027.

Description E-value Query
Range
Subject
Range
FBpp0293026, FBp... - type=protein; loc=X:join(17156803..17157011,17163964..17164147,17165255..17165437,17165521..17166738...
1142.0 [0..120] [1509..41]

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Predicted Domain #1
Region A:
Residues: [1-426]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTSLTSYRR SKQKSKSNND IHTIIATEVV TAAILSSSVH SSSTGSEIGD GGQGNTSLIE  60
   61 EAAAQDQSSE EQDRQHQHAK DPLAQTEMNH HPHSHHQRKS AVEVVRQQMD DDGDQDSNDD 120
  121 DETMPMMSGV GRKEQNNRRS VVSANTQMDN DVTPVYLAAQ EGHLEVLKFL VLEAGGSLYV 180
  181 RARDGMAPIH AASQMGCLDC LKWMVQDQGV DPNLRDGDGA TPLHFAASRG HLSVVRWLLN 240
  241 HGAKLSLDKY GKSPINDAAE NQQVECLNVL VQHGTSVDYN GKSSSQRHKS QQQLHQQHQQ 300
  301 QQQQQQQQHL SSSCNSNSNS SKQTSRSNTI KSKSSSTLSS DVEPFYLHPP ALAGGSGGSG 360
  361 MGLGMGMGMG MGMSMGLGIS RKNSDALYSQ QSRSSSEKLY NGSSSLGGNP GGNSSSGGGG 420
  421 VGGGGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 101.0
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.30812396303844 bayes_pls_golite062009
actin binding 3.15358758538214 bayes_pls_golite062009
structural constituent of cytoskeleton 2.4948065111495 bayes_pls_golite062009
binding 2.03195138036959 bayes_pls_golite062009
actin filament binding 1.8758804992293 bayes_pls_golite062009
protein binding 1.6716587413544 bayes_pls_golite062009
myosin binding 1.55894148251645 bayes_pls_golite062009
myosin phosphatase activity 0.991228379874891 bayes_pls_golite062009
structural constituent of muscle 0.304639267984357 bayes_pls_golite062009
structural molecule activity 0.242743465134414 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [427-659]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGGALLPNDG LYVNPMRNGG MYNTPSPNGS ISGESFFLHD PQDIIYNRVR DLFVDSDCSS  60
   61 SVKQHGKSHA HQLLQSKAGN AMTIQADVHS SSSGAGSGSD ESVSISSSFN SPKQQQQLRS 120
  121 QSFNRHGSSS NISASGNIKN NNYKAHKGKP SNQNGGGDHD YEDIYLVREE SRKQHQQQQQ 180
  181 HQLQQQQQLQ HQATQQQQQQ QQQQQQLQHK YNVGRSRSRD SGSHSRSASA SST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [660-819]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSTDIVLQYS NHHLNNKRNM NNNSNMNNSS SNIAQSSSSN NNNNSLLNRN KSHSIIGLHS  60
   61 SKYESSLKDN YSAKNVNLKN QLLNGGIKSD TYESVCPPED VAERTKQTHK NSMIRNNLAD 120
  121 ASSNNNTSGS INNISNIGNM NGGNQSSRNL KRVSSAPPMQ 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [820-921]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLAVVNGPPP PPLPPPLRAP VQQQRNNLSV DQPNSMTGNN GIYKKNVFGP NQGPTNANGT  60
   61 GGAAPPPVPA PNPVATEAVD SDSGLEVVEE PSLRPSELVR GN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [922-993]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HNRTMSTISA NKKAKLLNAG STNGSSIAAS SDDSQSRYGG SVHAANGSAA NGHFYGYSEG  60
   61 NKNQGSNGNG NG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [994-1241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGNGGGGNYH SHPNQPHYAT GQPHQYTPSL YGGGSSAEDH YELTQQQQQI YGETHLPSGQ  60
   61 RTGGPNLVNK QLVLPFVPPS FPNKSQDGVT HLIKPSEYLK SISIDKRSCP SSARSTDTED 120
  121 YMQIQIAQQQ SHPHQHQHHP HPHPHPHHPH QLHGMGEQPP LPPPPPPLPH GMLPPQPPMG 180
  181 PPMGVAGGQD ATMSGKSHKP KKPHGSAPNS QDTATRKQHQ PLSAISIQDL NSVQLRRTDT 240
  241 QKVPKPYQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1242-1314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPARSLSMQC LTSSTETYLK SDLIAELKIS KDIPGIKKMK VEQQMASRMD SEHYMEITKQ  60
   61 FSGNNYVDQI YLQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1315-1411]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPERDQAGNA IPDWKRQMMA KKAAERAKKD FEERMAQEAE SRRLSQIPQW KRDLLARREE  60
   61 TENKLKAAIY TPKVEENNRV ADTWRLKNRA MSIDNIN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1412-1509]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INLAGMEQHY QQIQFQQKQQ QLQLGNKENH VDPKGADQDQ EHGVGIGSGV GNANSGVIGG  60
   61 QELIDPSEGS QGRAEEEEDN IIPWRAQLRK TNSRLSLI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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