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Protein Overview: Stim-PA

General Information:
Name(s) found: Stim-PA / FBpp0073955 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Stromal interaction molecule is referred to in FlyBase by the symbol Dmel\Stim (CG9126, FBgn0045073). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15828933..15834468. It has the cytological map location 14A1. There is experimental evidence that it has the molecular function</span>: calcium-induced calcium release activity; store-operated calcium channel activity. There is experimental evidence that it is involved in the biological process</span>: bristle development; positive regulation of calcium ion transport via store-operated calcium channel activity; positive regulation of NFAT protein import into nucleus; activation of store-operated calcium channel activity; imaginal disc-derived wing morphogenesis. 11 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: adult segment; adult mesothoracic segment; organ system; peripheral nervous system; thoracic segment; nervous system; external compound sense organ; compound cell cluster organ; embryonic/larval fat body; wing hair; dorsal thoracic disc. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 570 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [NAS]
    Biological Process: positive regulation of NFAT protein import into nucleus [IMP]
    imaginal disc-derived wing morphogenesis [IMP]
    cell adhesion [NAS]
    bristle development [IMP]
    positive regulation of calcium ion transport via store-operated calcium channel activity [IMP]
    activation of store-operated calcium channel activity [IMP]
    Molecular Function: store-operated calcium channel activity [IMP]
    calcium-induced calcium release activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKNTIWNYS LIFFCCVLKS ISTLDHGPHT VSVDSNRHNT QHQYKQNPNV ASQRHSSHES  60
   61 GQSLHNSQSE HVTHIAASHA GSGGEHSTHL AQNLHRSSYN LLSEAMSQAV SNEFSSMGSG 120
  121 SADGACAADD FDCYSGSVQD RFGMEAIASL HRQLDDDDNG NIDLSESDDF LREELKYDSG 180
  181 YEKRQKAFHF NDDMHISVKE LWEAWLRSEV HNWTIEQTTD WLAQSVQLPQ YVDLFKLHKV 240
  241 TGAALPRLAV NNLQYVGNVL GIKDPIHKQK ISLKAMDVVL FGPPRETGTR WKDYILVTLL 300
  301 LSAIIGCWYA YQQNKNAKRH LRRMAQDMEG LQRAEQSLQE MQKELERARM EQENVATEKL 360
  361 DLERRLKEAP TLSSSNSDLE VQQLKKEIEM LRNELSRAEF ELVDNCWSPP PQLQSWLQYT 420
  421 YELESKNHQK KRTSAEKQLQ SAREACEKLR KKRSSLVGAF VSTHGKSIDD VDRSIVEARN 480
  481 ALGDVTNELQ ERLHRWKQIE TCLGLNIVNN NGLPYLENVL YGRNGGLQSS MGMSSTKGSR 540
  541 ARITNSTEDL DDESIQGKLN FENFSLLATE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..133] deduced N/A No confident structure predictions are available.
    2 View Details [134..474] PSI-BLAST 14.39794 Heavy meromyosin subfragment
    3 View Details [475..570] PSI-BLAST 9.0 Tropomyosin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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