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Protein Overview: Lcch3-PC

General Information:
Name(s) found: Lcch3-PC / FBpp0089263 [FlyBase]
Description(s) found:
Found 35 descriptions.
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  • The gene Ligand-gated chloride channel homolog 3 is referred to in FlyBase by the symbol Dmel\Lcch3 (CG17336, FBgn0010240). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15819089..15822562. It has the cytological map location 14A1. There is experimental evidence that it has the molecular function</span>: GABA-A receptor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ion transport. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 496 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEA]
    integral to membrane [IEA][NAS]
    plasma membrane [IDA]
    Biological Process: ion transport [IEA]
    Molecular Function: GABA-A receptor activity [IDA][NAS]
    extracellular ligand-gated ion channel activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTCFTRVGVS CGLFFFLLGA QLQLIRCIRK DVLAGRLENV TQTISNILQG YDIRLRPNFG  60
   61 GEPLHVGMDL TIASFDAISE VNMDYTITMY LNQYWRDERL AFNIFGQYFD DENDDGISDV 120
  121 LTLSGDFAEK IWVPDTFFAN DKNSFLHDVT ERNKLVRLGG DGAVTYGMRF TTTLACMMDL 180
  181 HYYPLDSQNC TVEIESYGYT VSDVVMYWKP TPVRGVEDAE LPQFTIIGYE TNDRKERLAT 240
  241 GVYQRLSLSF KLQRNIGYFV FQTYLPSILI VMLSWVSFWI NHEATSARVA LGITTVLTMT 300
  301 TISTGVRSSL PRISYVKAID IYLVMCFVFV FAALLEYAAV NYTYWGKRAK KKIKKVKECC 360
  361 PGKIGKSERS ETCSTTEDII ELQDVRMSPI PSLRRGTYNA TLDSIGTETM NLGKFPPSFR 420
  421 ITRNYGTGHS QLRRRAQRGI STRPRMLHAL KRGASAIKAT IPKIKDVNII DKYSRMIFPI 480
  481 SFLAFNLGYW LFYILE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..416] PSI-BLAST 55.0 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    2 View Details [417..496] PSI-BLAST 33.0 Acetylcholine receptor protein, beta chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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