Protein Overview: CG8184-PB

General Information:
Name(s) found:	CG8184-PB / FBpp0073898 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24642256\|ref\|NP_573059.1\| CG8184 [Drosophila melanogaster] [NCBI NR] gi\|22832284\|gb\|AAF48495.2\| CG8184 [Drosophila melanogaster] [NCBI NR] This gene is referred to in FlyBase by the symbol Dmel\CG8184 (CG8184, FBgn0030674). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15608148..15625521. It has the cytological map location 13E8-13E12. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process</span>: dsRNA transport. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG8184-PB translation from_gene[CG8184 CG8184 FBgn0030674] seq_release:3 mol_weight=556865 cds_boundaries:(X:15,445,129..15,462,158[+]) aa_length:5146 transcript_info:[CG8184-RB seq_release:3] gene_info:[gene symbol:CG8184 FBgn0030674 gene_boundaries: [hmr_yeast5_DM3-1_pombe.fasta] (Q9VXR3) CG8184 protein [DrosMelano7227.FASTAC.txt] CG8184-PB [Drosophila melanogaster]gi\|24642256\|ref\|NP_573059.1\| CG8184-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=X:join(15608148..15608414,15608750..15608989,15609059..15609280,15609339..15609610,15609691..15610187,15610325..15615432,15615597..15618411,15618475..15618948,15619007..15619347,15619410..15620480,15620571..15620706,15620766..15623390,15 [fly-100309-contam.fasta] CG8184-PB [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=X:join(15608148..15608414,15608750..15608989,15609059..15609280,15609339..15609610,15609691..15610187,15610325..15615432,15615597..15618411,15618475..15618948,15619007..15619347,15619410..15620480,15620571..15620706,15620766..15623390,15623463..15623864,15623932..15624120,15624185..15624506,15624570..15624735,15624810..15625000,15625078..15625180); ID=FBpp0073898; name=CG8184-PB; parent=FBgn0030674,FBtr0074082; dbxref=FlyBase:FBpp0073898,FlyBase_Annotation_IDs:CG8184-PB,GB_protein:AAF48495.2,FlyBase_Annotation_IDs:CG8184-PA,REFSEQ:NP_573059,GB_protein:AAF48495; MD5=7859cf0ad5e11ee005415eca3e13bc63; length=5146; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=X:join(15608148..15608414,15608750..15608989,15609059..15609280,15609339..15609610,15609691..15610187,15610325..15615432,15615597..15618411,15618475..15618948,15619007..15619347,15619410..15620480,15620571..15620706,15620766..15623390,15623463..15623864,15623932..15624120,15624185..15624506,15624570..15624735,15624810..15625000,15625078..15625180); ID=FBpp0073898; name=CG8184-PB; parent=FBgn0030674,FBtr0074082; dbxref=FlyBase:FBpp0073898,FlyBase_Annotation_IDs:CG8184-PB,GB_protein:AAF48495.2,FlyBase_Annotation_IDs:CG8184-PA,REFSEQ:NP_573059,GB_protein:AAF48495; MD5=7859cf0ad5e11ee005415eca3e13bc63; length=5146; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] CG8184 OS=Drosophila melanogaster GN=CG8184 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=X:join(15608148..15608414,15608750..15608989,15609059..15609280,15609339..15609610,15609691..15610187,15610325..15615432,15615597..15618411,15618475..15618948,15619007..15619347,15619410..15620480,15620571..15620706,15620766..15623390,15623463..15623864,15623932..15624120,15624185..15624506,15624570..15624735,15624810..15625000,15625078..15625180); ID=FBpp0073898; name=CG8184-PB; parent=FBgn0030674,FBtr0074082; dbxref=FlyBase:FBpp0073898,FlyBase_Annotation_IDs:CG8184-PB,GB_protein:AAF48495.2,FlyBase_Annotation_IDs:CG8184-PA,REFSEQ:NP_573059,GB_protein:AAF48495,FlyMine:FBpp0073898,modMine:FBpp0073898; MD5=7859cf0ad5e11ee005415eca3e13bc63; length=5146; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] CG8184 OS=Drosophila melanogaster GN=CG8184 PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=X:join(15714115..15714381,15714717..15714956,15715026..15715247,15715306..15715577,15715658..15716154,15716292..15721399,15721564..15724378,15724442..15724915,15724974..15725314,15725377..15726447,15726538..15726673,15726733..15729357,15729430..15729831,15729899..15730087,15730152..15730473,15730537..15730702,15730777..15730967,15731045..15731147); ID=FBpp0073898; name=CG8184-PB; parent=FBgn0030674,FBtr0074082; dbxref=FlyBase:FBpp0073898,FlyBase_Annotation_IDs:CG8184-PB,GB_protein:AAF48495.2,FlyBase_Annotation_IDs:CG8184-PA,REFSEQ:NP_573059,GB_protein:AAF48495,FlyMine:FBpp0073898,modMine:FBpp0073898; MD5=7859cf0ad5e11ee005415eca3e13bc63; length=5146; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=X:join(15714115..15714381,15714717..15714956,15715026..15715247,15715306..15715577,15715658..15716154,15716292..15721399,15721564..15724378,15724442..15724915,15724974..15725314,15725377..15726447,15726538..15726673,15726733..15729357,15729430..15729831,15729899..15730087,15730152..15730473,15730537..15730702,15730777..15730967,15731045..15731147); ID=FBpp0073898; name=CG8184-PB; parent=FBgn0030674,FBtr0074082; dbxref=FlyBase:FBpp0073898,FlyBase_Annotation_IDs:CG8184-PB,GB_protein:AAF48495.2,FlyBase_Annotation_IDs:CG8184-PA,REFSEQ:NP_573059,GB_protein:AAF48495,FlyMine:FBpp0073898,modMine:FBpp0073898; MD5=7859cf0ad5e11ee005415eca3e13bc63; length=5146; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of X2JF73, CG8184, isoform B OS=Drosophila melanogaster GN=CG8184 PE=1 SV=2 [DROME.fasta.20160308] FBpp0073898 type=protein; loc=X:join(15714115..15714381,15714717..15714956,15715026..15715247,15715306..15715577,15715658..15716154,15716292..15721399,15721564..15724378,15724442..15724915,15724974..15725314,15725377..15726447,15726538..15726673,15726733..15729357,15729430..15729831,15729899..15730087,15730152..15730473,15730537..15730702,15730777..15730967,15731045..15731147); ID=FBpp0073898; name=CG8184-PB; parent=FBgn0030674,FBtr0074082; dbxref=FlyBase:FBpp0073898,FlyBase_Annotation_IDs:CG8184-PB,GB_protein:AAF48495.2,FlyBase_Annotation_IDs:CG8184-PA,REFSEQ:NP_573059,GB_protein:AAF48495,FlyMine:FBpp0073898,modMine:FBpp0073898; MD5=7859cf0ad5e11ee005415eca3e13bc63; length=5146; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=X:join(15714115..15714381,15714717..15714956,15715026..15715247,15715306..15715577,15715658..15716154,15716292..15721399,15721564..15724378,15724442..15724915,15724974..15725314,15725377..15726447,15726538..15726673,15726733..15729357,15729430..15729831,15729899..15730087,15730152..15730473,15730537..15730702,15730777..15730967,15731045..15731147); ID=FBpp0073898; name=CG8184-PB; parent=FBgn0030674,FBtr0074082; dbxref=FlyBase:FBpp0073898,FlyBase_Annotation_IDs:CG8184-PB,GB_protein:AAF48495.2,FlyBase_Annotation_IDs:CG8184-PA,REFSEQ:NP_573059,GB_protein:AAF48495,UniProt/TrEMBL:Q9VXR3,FlyMine:FBpp0073898,modMine:FBpp0073898; MD5=7859cf0ad5e11ee005415eca3e13bc63; length=5146; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	5146 amino acids
Gene Ontology:
Cellular Component:	intracellular [IEA]
Biological Process:	protein modification process [IEA] dsRNA transport [IMP]
Molecular Function:	ubiquitin-protein ligase activity [ISS] binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVDTVKLKK GSSELTAECR ELIDELTKRR TRAELLEFLD TVHVWIYGKC ELYHWIEILD  60
   61 RFDKILEEAS RHVNGNEFVL QCDTNFQETD VTLLLHVLNF TTLLIEHSFS RHLYNSIEHL 120
  121 TVLLSSQNMD IVLAVLNLLY MFSKRSNFIP RLPFEKKELL IVKLFNIAER WGDPNYGLSL 180
  181 KDCCIGEPKL EFLYQLCIDY VDEHGHAAQL EIPDMMDLCH TASAPEVIKT IAGQISKPSE 240
  241 AIKMRIAHRV RLISGFNNYK LRLQFVQARL QAVSILIYSN ALQDNTDKVL YAGFGEELCE 300
  301 LIDKEDVHLV EIRAAVLRTL TSMLHFDRNP NVPSRAGSRL MKIVHYTGAE RQGGTLPLLV 360
  361 RDCIDNLTTH GLTERYPLIL ATSLFSLLYH LASYEMGGTA LVKSGMMQSL LCVISWPGVD 420
  421 LEHITFVTRA VRVIDLITNI DIARFHQNNG LNVFIDRLEK EIKSCCKALA DIGITLKEST 480
  481 LRDDHKLDTS LDHVDEDVED GSGENASVTS GNASPRRDNS SDGATGAGSI VYRAYHEHIG 540
  541 GAGSGAGLLD IGGARSSLSG GSSGTSGMGA GSINRDGSAA RPPAIMYPTN SYYARPLAER 600
  601 KAELSSQLPS SLAPKKPSCV TQRAALLKSM LNFLKKSIQD HAHFSNMRNI METSLTQSLR 660
  661 HIIANAEYYG PSLFLLATDV VTVYVFNEPS LLSSLQDLGI TSVMLKALLQ KDVPATREVL 720
  721 GSLPNVFSAL CLNERGLFEF LSYDPFDKVL KVLLSPDYLV AMRRRRSSDP LGDTATNLGN 780
  781 AMDDLIKHHP YLRADATEAI VRLLNELVRL GSDPSFICWR ANKESSGSGS GSGSHGGGHH 840
  841 VASTPSPMVM VAGTGSASSV LQGAADTNDS SGDDDDDDDE MSSASQQQQQ PTTPGQGGGP 900
  901 STPRTQQAGG VVGSGAGATG TPAAASQAVK VVTPPEREAI PLIDYILNVM KFIEAIFSNS 960
  961 PNGDHCREFV LHGGLKPILQ LLSLPNLPVD SPVSTTSQAV ANVCKAILSQ AQETKVLDVA1020
 1021 LKQLADIVAQ LKPLIKHFTF PGGSVLLAEL VCCQRLEDGF ANAEYTPILH NMSFVHGYVV1080
 1081 MLVHLCRNAS NDMRTILLKR WGVNRETGVQ LLQQLVQLYI SLVWESTILL NLCSDEPTQH1140
 1141 PDLIWDEIAA QMSAAAGTAD PLTEAELSRK LERAAEFRTK YTPEEQFRYI KSLLAASSRL1200
 1201 GRALAELLGT LVKLSVGSPQ TRQRRINDLI SNITKVPTPE AREIARILSS ILVNGFSHES1260
 1261 ILPKPVPKLK LTFLICSVGF TGPMLFDDKR SAFHLMISQF CAENGLKAFF EMFYWALSLD1320
 1321 NVSQKFEFDQ WASMEDLMQS HEDDKRDCPE GTGEFLDAWL QLLEKMVNPR AMLDSPYTMS1380
 1381 PRLNYMPDSV PFEPVFYLIH IHQLAMQALR RIWARRPIPN YGPSMFETMI LILKHLIKSH1440
 1441 QTLLDRYHTR MKEIKFENLY IRSTDDGLNA DHIKTLTDMG FMHYHVIEAL RTNASLEEAT1500
 1501 DYLLNNPEAS SLSTTGGQSS SSAPPPPPPP SASTMDIDVD VPADGESTQS KSSTSPNSSY1560
 1561 DYKHLKLMPS LIFDRFCDEA ISRAFEFMEA IPDTVNSAAD LIAVLYRRHN HLNKQVFVTN1620
 1621 FVRNIIQWVD FTLQLFEPAK TTGSKASRLE ECLTGMTATR LFVRLKTSTL LLEENYSDLH1680
 1681 RPLVEAITAQ DAMVSLVKLL DCMSQWMLEQ STETNTGQQR ATVPRWVQNL VDLIDAIDSI1740
 1741 SHILQRKANM RAVSSDVWRW YDASTGKWNA YSEANNELIR NAYAAGERWL YINIGRQRCT1800
 1801 VSLNCMTQVS EASGTHRPVC PALKLSEAIT SLNNPVALHK VEHILNRVVR TAPDGSGTVH1860
 1861 SDELISLRQL VNFTDGQQPQ QSENSANPSE EATSEDGPAA ANSGSPPATM TTRSKTRQKS1920
 1921 AAAAAAAKNK SQSGGSPPIP KRTQKIILNE EQVGLSKFDC GRIIGSIVDL LQPSHQMLNE1980
 1981 TKLSLLRLCA RLTRNYDNAQ VFIRRGGVRM LLHLQQACSF MGFPTYANII LRHVLEAPPV2040
 2041 LQEAMERVLG MRAAGIVPVG HRDLIYVLTQ VSSAVSRNPQ IFVAAAKEML KGEYLINTNS2100
 2101 TTLADDARVM VKSKFGQQPT AAAGGATPHN QTPTPPPAAK DELKDDPQVQ SSVAVLKELL2160
 2161 HGLVQPCWHY GGTGSLDRGQ GAAELLQPDQ PPGTAQGCHD DEETPAPVSS KKQSSSGGGA2220
 2221 AAAGQTGQAT EKFEPCCCTW HIPTSGHTHA KPTISRATLL KLLADSTRAY QSLVPRVLLS2280
 2281 HVYTPADSPL ISAPQQTFLG VLLDRFLPIT QRHHVPEVST MTRVLICSLS DCYQQPGVQV2340
 2341 HVAEELHAAV ARALAQPDSA EKHTRLQVLM SLFPNLIESP MLYDKVHMHR NNMYRVLLRQ2400
 2401 GVMTYLTKVA QYKDLSNHNT LSTLAAILRP MEILLRFSVS TTTLGSKRIL FGSGGPGGPN2460
 2461 ASGNGNNTAG GSSGNGPGSG NTYGTIINRR LYPRLAARTG FGSAMERSNA MGGEHVLRDI2520
 2521 IRNVLSDRRH AFEFIFNSDD MAVDSEDAAA PGSGVGGGGS GAGSVGGGVS GSVSGNSSAA2580
 2581 VIDVVEERSN GGDTNDPPAN VSSASSGAGQ SSTSGGPVRP VVNFDQLWDD FLQSEGLRLA2640
 2641 SRSGGGAGSG SGSVGASSSG QQNGSNTTAS STNSGNNSGI GNLRLRTNPD VDVGSGNGSG2700
 2701 SGSGSNAGVV NDNGISGGGG SDGASTSSDT GAPGGARDLN ASLLGDVSTS ESDSDPSTEN2760
 2761 DERNEEDEDE DDDAPDEDVD EHSETDVDEE RSRQFIEVFD HIYEPESSET ASNDADVDND2820
 2821 DDDDEDDVDD DDDDDEDNDD DVREEVQSVM DAEIENRIDI ALALVSSNNR PRRSAAVNAS2880
 2881 GDGSANRTNP DDEVDDEDDD VDADPDGDPD VDPISGPSAA QAEAYLYERL GSGLMPTPPV2940
 2941 GFRVRMNSSI AQPLDIDVNG GNAGSGSNAG ATGSSGGSGQ RSSTGGTTAS IGAIASAALR3000
 3001 PSSGSWMAPD FNFIRISGGD SSMGSGPAIG GNANGGDMNV FITPSMSLER AGGAPGSGQT3060
 3061 MSELLNEQPT GAGGGGGGGS ASGVGGVGAN GGTTGQHPNA TLCTNGVRRR LLYLDQQYCV3120
 3121 CMPTHQNPTE ETQMETFTQD ALHWWLEEAT LLDMESQTDA CLYAAHFLLP HLIKELKAAH3180
 3181 QQRKQEEAAR QSTTPASGSN ASATSSSTTS VVGTAAPTAT SSIASGLLAN AVSAGSGSSS3240
 3241 LVVPPVAASA TGGTRRSSIP VLISSTLGPS SASSATSATG NGATSDATTT TGGPTRNFSS3300
 3301 VDSNVSSETQ TTTRPPRQRG GLRQQSQLPF NIYAEIDLTN EQDSEGDRST STTTGTAADG3360
 3361 AESQSQHNSS STAAQVAVPQ HQRHPPVPLL PSSGRPSRPH TRLDETELLL LQLTDRQIRN3420
 3421 RLQGSSGHTN SSRTSGSALI NARPNRDLPA CLQRHDHPAG SIFPRPSANR TPAPTLVSMP3480
 3481 TPMSNAALEQ LNVTAPDVVR TDRNFALPSS LEVDVDVLPG IVDLPQQEAQ PEDDQLLLPP3540
 3541 PPPPPPSDTT PLVHAEDDLW PGTVVSAGTR EESSAPAVAT ESTEAVNESN QPEPTPESSE3600
 3601 STSPNPQAPS AEPTPLEPGA AVDASVGAQT PATTEEAAST AGASGTTATI TDMSPEVRAA3660
 3661 LGDLEVPEGV DPSFLAALPS EMREEVIQEH LRMQRIRQRA QQNAIQIAHD SLVEVNPEFL3720
 3721 AALPLNIQSE VLMQQRIEQQ RQAAQTANPE DPVDTAAFFQ NLPENLRQAI LTDMEESQIA3780
 3781 SLPPELAAEA QFLRRDWESR NGARMDAHPP SNALSRFQTT LQSLDDTRWH SSIWYDASGN3840
 3841 AQPQHHQHTT IVHQHPHAHH APNMGKPLAL LMMEDENILL DPDSLATLLL FLFVEDQKVN3900
 3901 SMRLHRVIRN LCHHEPTRDW IISALISIIQ KTNEDNANFG AGQAGGKPEW LKLRVDAAFG3960
 3961 YKSNIFLINR LYEGSARSIS INPQAAQMIV RNCLDLLFVL AKHYPSSFVP FNRDVKARRI4020
 4021 LSAVFGMPSP TAGSGGGAGS GSAASGGLTG YDDVPPGGTL DFRSRFCRYQ VVNRLRSIFD4080
 4081 DHPAPKPSVP LDEAPSTSKA AAAKAAATAK VSTAGSQNKH SVPYQTNAKN FWDVVLNIDQ4140
 4141 QTQVRLANVA QFPLTSQPAW EWQPNTADFL SFSESPFGQL LEMLPYKVIC RSPHLTDMLV4200
 4201 KLLASLSTEL PKEEELLPLS DQMPPLVPIG PVQRAGAAAA AAHPPPPQPP AENTATATEI4260
 4261 GDGLAANIEE QASPASGNPA SGDSNAGAKR TQLPTLSVAL PVTPSKPRRK IYSKNFSQLQ4320
 4321 LVIEVLTHQC GTTEGLDNVA KLIVNLTQCS QASSAIFIQY LTAAILGLAE EVRQAIQMLL4380
 4381 NEIRMYNIHQ GGAGTTSQAA STSGAAAATA SYVPTVSGAS LLPNLAVHEG IMQDRFTAEH4440
 4441 VIISAPKNAK PTCELQLPSM KKLMSNSSAQ PYFLRTLKIF MQVRDMYEAQ NGLSTGGGVA4500
 4501 CGAGDNDDDI IDIEGDGGAS GGSSSDMAPG SASTISPPPP METNQIAQDG DDDEEDDDEA4560
 4561 RSFPGVGNHA VASASKSTKP TLSQILCLDV LWNTLSECLV ALEESKDEFA VLVLQPTVEA4620
 4621 FFLIHASHRG ASKKSGRSFM PNAAGFGLRA AAGAGAIGGL GAAAPSAQEY SPFMDDVSSA4680
 4681 NTPSSASFDD EPRMQDASTN TPLVTNPSTS TAMSAHEAQL RQDRQKFLQF AEKHRTVLNQ4740
 4741 ILRQSPTHLS DGPFAVLVDH TRILDFDVKR KYFQTELERL DEGIRREEHT VSVRRVTVFE4800
 4801 DSFRVLYRLG PEEWKNRFYI VFEDEEGQDA GGLLREWYVI ISREIFNPMY ALFCVSPGDR4860
 4861 VTYMINPSSH ANPNHLSYFK FVGRVIAKAV HDNKLLECYF TRSFYKHILG KQVKHTDMES4920
 4921 QDYEFYKGLD YLMKNDISTL GYELTFSTEV QEFGVTQIRD LKPNGRDTAV TEENKFEYVQ4980
 4981 LVCQLKMSGS IRQQLDAFLE GFYDIIPKHL ISIFNEQELE LLISGLPDID IEDLKANTEY5040
 5041 HKYTSKSAQI QWFWRALRSF DQADRAKFLQ FVTGTSKVPL QGFGSLEGMN GIQKFQIHRD5100
 5101 DRSTDRLPCA HTCFNQLDLP MYKSYDKLRS CLLKAIHECS EGFGFA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.59

Protein Overview: CG8184-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: