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Protein Overview: Ndc80-PA

General Information:
Name(s) found: Ndc80-PA / FBpp0073681 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Ndc80 is referred to in FlyBase by the symbol Dmel\Ndc80 (CG9938, FBgn0030500). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:13503698..13506009. It has the cytological map location 12A8. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitotic metaphase plate congression; chromosome segregation; mitotic spindle organization. 10 alleles are reported. The phenotypes of these alleles are annotated with: metaphase; condensed nuclear chromosome; spindle; nucleus. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 675 amino acids

    Gene Ontology:
    Cellular Component: Ndc80 complex [IDA]
    kinetochore [IDA]
    Biological Process: mitotic spindle organization [IMP]
    chromosome segregation [IMP]
    mitotic metaphase plate congression [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHLMPRRTS EFRGDVLEER GTADKRQTRA TKRSAATHTP SSSQAAPRRP SASRLPQPLN  60
   61 LERDRASQMG VTPKRGHRFV PSTAERAIAP HSDKKWVAER AQQILEYLHG IQNSEAPTGL 120
  121 IADLFSRPGG LRHMTIKQFV SILNFMFHHI WRNRVTVGQN HVEDITSAMQ KLQYPYQVNK 180
  181 SWLVSPTTQH SFGHVIVLLD FLMDFLPPLP SSDVVEEEFP FMETMEQPSS YLNSMHCEST 240
  241 TIMSTTQAHA IQLDEDVNGL LFEEASKCIA LWDQELTNEE AKLQAETRDQ VISKKCDLPD 300
  301 RKALDQLIGD LKTKLQQLEN KLHDPSEDNK LNKLERLTKE HDQLAQQLAA SEEELIKKLK 360
  361 LYEQLSAQVE EKQSNLRQQM KYEKRLEQAV NRQKFSAQQL KELQMKCDDM ENYSKAYERQ 420
  421 VKEVSELELH QQVMLSRAKQ KQLDSVEVFN SHVRHLSMDP VICGLIKSGI GQQSDLTLPL 480
  481 NPNQEDISER VQCLELLGKL LQQHRQQNID RRQMLDKQVA KVKSDSIELD TEIATMDSQL 540
  541 RAQKQRLTKM EASYRTKRDM QAQHRQQLLE DQYDQTARLD ELEKREKQAL EKLEASKQRN 600
  601 EDLLTAAEQF QEQDLKARQD RLEKCEQKLA KAEDQLLAVE SKVNATQAKL NEVEQKVYSA 660
  661 KLPSFQPVLD AIKNH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..62] deduced N/A No confident structure predictions are available.
    2 View Details [63..176] PSI-BLAST 43.30103 No description for 2igpA was found.
    3 View Details [177..546] PSI-BLAST 35.522879 Heavy meromyosin subfragment
    4 View Details [547..675] PSI-BLAST 4.154902 No description for 2iw5A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle