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View Structure Prediction Details

Protein: Ndc80-PA
Organism: Drosophila melanogaster
Length: 675 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ndc80-PA.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
284.0 [0..183] [670..1796]

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Predicted Domain #1
Region A:
Residues: [1-62]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHLMPRRTS EFRGDVLEER GTADKRQTRA TKRSAATHTP SSSQAAPRRP SASRLPQPLN  60
   61 LE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [63-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDRASQMGVT PKRGHRFVPS TAERAIAPHS DKKWVAERAQ QILEYLHGIQ NSEAPTGLIA  60
   61 DLFSRPGGLR HMTIKQFVSI LNFMFHHIWR NRVTVGQNHV EDITSAMQKL QYPY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.30103
Match: 2igpA
Description: No description for 2igpA was found.

Predicted Domain #3
Region A:
Residues: [177-546]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVNKSWLVSP TTQHSFGHVI VLLDFLMDFL PPLPSSDVVE EEFPFMETME QPSSYLNSMH  60
   61 CESTTIMSTT QAHAIQLDED VNGLLFEEAS KCIALWDQEL TNEEAKLQAE TRDQVISKKC 120
  121 DLPDRKALDQ LIGDLKTKLQ QLENKLHDPS EDNKLNKLER LTKEHDQLAQ QLAASEEELI 180
  181 KKLKLYEQLS AQVEEKQSNL RQQMKYEKRL EQAVNRQKFS AQQLKELQMK CDDMENYSKA 240
  241 YERQVKEVSE LELHQQVMLS RAKQKQLDSV EVFNSHVRHL SMDPVICGLI KSGIGQQSDL 300
  301 TLPLNPNQED ISERVQCLEL LGKLLQQHRQ QNIDRRQMLD KQVAKVKSDS IELDTEIATM 360
  361 DSQLRAQKQR 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.522879
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [547-675]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTKMEASYRT KRDMQAQHRQ QLLEDQYDQT ARLDELEKRE KQALEKLEAS KQRNEDLLTA  60
   61 AEQFQEQDLK ARQDRLEKCE QKLAKAEDQL LAVESKVNAT QAKLNEVEQK VYSAKLPSFQ 120
  121 PVLDAIKNH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 2iw5A
Description: No description for 2iw5A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle