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Protein Overview: lic-PA

General Information:
Name(s) found: lic-PA / FBpp0073551 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • The gene licorne is referred to in FlyBase by the symbol Dmel\lic (CG12244, FBgn0261524). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:12985156..12988026. It has the cytological map location 11D10. There is experimental evidence that it has the molecular function</span>: MAP kinase kinase activity; protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: oocyte axis specification; transforming growth factor beta receptor signaling pathway; activation of MAPK activity; mucosal immune response. 14 alleles are reported. The phenotypes of these alleles are annotated with: embryonic segment; egg; pole cell; egg chamber; dorsal appendage. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 334 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: activation of MAPK activity [IDA]
    oocyte axis specification [IMP]
    transforming growth factor beta receptor signaling pathway [IGI]
    protein amino acid phosphorylation [NAS]
    mucosal immune response [IMP]
    oocyte anterior/posterior axis specification [NAS]
    Molecular Function: ATP binding [IEA]
    receptor signaling protein serine/threonine kinase activity [NAS]
    MAP kinase kinase activity [IDA][ISS][NAS][TAS]
    protein kinase activity [IDA]
    protein serine/threonine kinase activity [IEA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRHRLTPF TIAKEPEAAI VPPRNLDSRA TIQIGDRTFD IDADSLEKIC DLGRGAYGIV  60
   61 DKMRHKQTDT VLAVKRIPMT VNIREQHRLV MDLDISMRSS DCPYTVHFYG AMYREGDVWI 120
  121 CMEVMSTSLD KFYPKVFLHD LRMEESVLGK IAMSVVSALH YLHAQLKVIH RDVKPSNILI 180
  181 NRAGQVKICD FGISGYLVDS IAKTIDAGCK PYMAPERIDP QGNPAQYDIR SDVWSLGIGM 240
  241 IEMATGRYPY DNWRTPFEQL RQVVEDSPPR LPEGTFSPEF EDFIAVCLQK EYMARPNYEQ 300
  301 LLKHSFIVEH LQRNTDISEF VARILDLPDA QPAQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..334] PSI-BLAST 56.221849 No description for 2dylA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle