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Protein Overview: CG42249-PB

General Information:
Name(s) found: CG42249-PB / FBpp0288787 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG42249 (CG42249, FBgn0259101). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10990306..11002192. It has the cytological map location 10A4. Based on sequence similarity, it is predicted to have molecular function</span>: 5'-nucleotidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: nucleotide catabolic process. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 557 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nucleotide catabolic process [IEA]
    Molecular Function: nucleotide binding [IEA]
    5'-nucleotidase activity [ISS]
    metal ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATACNRLTW SLVVVVAVMA VMCSSAEAAD KEGFPVAIIH INDLHARFEA TDTSGGTCDE  60
   61 GEECIGGYPR TVYTVKRLLQ EQAELNPIYI NAGDSFQGTL WYNIGRWNVT QQLLNLLPAD 120
  121 VMTLGNHEFD HGVEGVVPFL ETVDTNMLVA NMDCAHEPTM EGKYNKSMII ERSGRKIGVI 180
  181 GVILETTYDL ANTGKVIFRN ESDTIREEAQ LLKAQGANII IVVSHCGYDV DQQIAANAGD 240
  241 WIDVIVGSHS HTFLYTGDPP GPHTPSGDYP TEVIHSSGHR VLIVQASAYA RYVGNLIVYF 300
  301 DDNGDVLDYE GDPLYMDQSV PEDEEVLVAM QPWKEVIDET GKVVVGNTKV DLTKDDCAAG 360
  361 ECNLGNFFCD AMVHSFVGMA SYEEKVWTNV SAGLMNIGGL RVPLNRGNLT YAHIVSMSPF 420
  421 ENTLVSYNLP GSKIVEAMEW ALSKVDLENG VTGSYINLQF SGIRAKYDYT KPVGSRVISV 480
  481 TIRCADCEVP KYEPLVSDKL YRLTSPNFLQ AGGDGYTMLA EGTDLQWGVT DLDALISYSN 540
  541 HINPIYQGLE GRITVLN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..557] PSI-BLAST 94.045757 5'-NUCLEOTIDASE FROM E. COLI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  6.90309911517124 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.76617976580319 bayes_pls_golite062009
  • phosphatase activity
    		•  6.28072946025083 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.93537144836081 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  5.11265802430394 bayes_pls_golite062009
  • hydrolase activity
    		•  2.06280293513737 bayes_pls_golite062009
  • catalytic activity
    		•  1.39852585255405 bayes_pls_golite062009
  • binding
    		•  0.607014751804583 bayes_pls_golite062009
  • calcium-dependent protein serine/threonine phosphatase activity
    		•  0.598330833036731 bayes_pls_golite062009
  • protein kinase activity
    		•  0.55395641922978 bayes_pls_golite062009
  • signal transducer activity
    		•  0.541715460439478 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.541715460439478 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.395006104431866 bayes_pls_golite062009
  • kinase activity
    		•  0.366390322110727 bayes_pls_golite062009
  • protein binding
    		•  0.184079020957384 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.39246790349923E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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