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Protein Overview: v-PA

General Information:
Name(s) found: v-PA / FBpp0073242 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • The gene vermilion is referred to in FlyBase by the symbol Dmel\v (CG2155, FBgn0003965). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10818023..10819671. It has the cytological map location 9F11. Based on sequence similarity, it is predicted to have molecular function</span>: tryptophan 2,3-dioxygenase activity. There is experimental evidence that it is involved in the biological process</span>: ommochrome biosynthetic process. 733 alleles are reported. The phenotypes of these alleles are annotated with: eye; ocellus pigment granule; pigment cell. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 379 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: tryptophan catabolic process [TAS]
    ommochrome biosynthetic process [IMP][NAS]
    tryptophan catabolic process to kynurenine [IEA]
    oxidation reduction [IEA]
    compound eye pigmentation [TAS]
    Molecular Function: tryptophan 2,3-dioxygenase activity [ISS][TAS]
    iron ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSCPYAGNGN DHDDSAVPLT TEVGKIYGEY LMLDKLLDAQ CMLSEEDKRP VHDEHLFIIT  60
   61 HQAYELWFKQ IIFEFDSIRD MLDAEVIDET KTLEIVKRLN RVVLILKLLV DQVPILETMT 120
  121 PLDFMDFRKY LAPASGFQSL QFRLIENKLG VLTEQRVRYN QKYSDVFSDE EARNSIRNSE 180
  181 KDPSLLELVQ RWLERTPGLE ESGFNFWAKF QESVDRFLEA QVQSAMEEPV EKAKNYRLMD 240
  241 IEKRREVYRS IFDPAVHDAL VRRGDRRFSH RALQGAIMIT FYRDEPRFSQ PHQLLTLLMD 300
  301 IDSLITKWRY NHVIMVQRMI GSQQLGTGGS SGYQYLRSTL SDRYKVFLDL FNLSTFLIPR 360
  361 EAIPPLDETI RKKLINKSV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..379] PSI-BLAST 91.39794 No description for 2noxA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle