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Protein Overview: CG2990-PB

General Information:
Name(s) found: CG2990-PB / FBpp0071350 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG2990 (CG2990, FBgn0030170). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:9904536..9908312. It has the cytological map location 9A4. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent DNA helicase activity; single-stranded DNA specific endodeoxyribonuclease activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: DNA replication. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1100 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: DNA replication [IEA]
    Molecular Function: DNA binding [IEA]
    ATP binding [IEA]
    ATP-dependent DNA helicase activity [ISS]
    single-stranded DNA specific endodeoxyribonuclease activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKRVLTPN ILENDNTDVT SSNPQKKFKE QLDFSSDEVE NIDWGDNDDF DLALIAAMDS  60
   61 ISNHRLELTK WQRCEVVRLE QLPNRKGLKV HVKRISGGDP ETADCQLLPP WNCMPMQVGD 120
  121 TVSLLGKWDP SAGCYVVDKE QGYCVSHPDF LISGTTVTGS LFCKRKSVLQ ERFRGLDSGN 180
  181 SVMVIGTLVH ELLQKVLRQK LFDKKHIQSA LQEMLASSSL AHLLYASNLI QVEMEDHLMK 240
  241 FIDPIVSFVA QYVKGEPPSV LLPEVYRGQI HEICDIEENL WVPQLGLKGK VDVSVKVKNQ 300
  301 RQREEIIPLE LKTGRASFSM EHKGQLLLYQ LMHSAQGRDT QSGLLLYLKE GLLREVASGR 360
  361 NEQRDLLMLR NDLAYWLTRE VAIPASKEDP LEQLPLPEPV YHHSACGNCA YNTICSSFAQ 420
  421 KDSSLQLSDS HPLKKLMPQL LEHLSEADHA YVQHWCGLLA LEEQHNRQSS HVRSFWTKDP 480
  481 AEREKEGIAI RHLKLVKGQE VILEEGRYRQ TLELGEEADP SRDLSLSGFD LGEYVVISST 540
  541 SRLAVAAGFI VSIEARRLDL RLERDLSQRY SEETFIIDKH DSQSFATFNF TNLGMLLSEG 600
  601 ERFQELRDII VAKKPPEQHK VLPKIILTKG APILLNLNKV QQNAALRALT TSSHLLIKGL 660
  661 PGTGKTQTLV ALVRLLHLLG KSVLITAQTH SAVDNLIMRL LPFGLPMMRL GSGSRIHKQL 720
  721 EEISEERLTK DCKTVEELEK ALGQPSIVGV TCLGCGHPLF QRRQFDYCIV DEATQVLQPT 780
  781 VLRPLIHCSK FVLVGDPEQL PPIVRSKEAR QRGADETLFQ RLDSEKATAV LSLQYRMNKT 840
  841 ITRLANELTY GGDLKCASDE VSGARFEVEL LNEAPRWVQR ALTTHLEQAV TLINTGDCLE 900
  901 RCQEFVYASQ RLVDTCSSIE QSFSEDKDEI RKLTSKKRVS KYTNYCEAGI VMHLLRYLLK 960
  961 SGYEASRIGV IAPYRAQVEL FKKLASKLDT DLECNTVDQF QGRDKNLIIY SCSKTGGDFS1020
 1021 DMERSREAEI LEDQRRLTVA ITRAKNKLIL LGDIKCLEQY GPFRQLFKHI PDRCRLKLEE1080
 1081 GRMEFGWQRI QEDLVGLMDT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..219] deduced N/A No confident structure predictions are available.
    2 View Details [220..428] MSA 2.216996 View MSA. No confident structure predictions are available.
    3 View Details [429..1100] PSI-BLAST 90.69897 No description for 2gjkA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle