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Protein Overview: sn-PA, sn-PB, sn...

General Information:
Name(s) found: sn-PG / FBpp0290893 [FlyBase]
sn-PE / FBpp0290891 [FlyBase]
sn-PB / FBpp0071058 [FlyBase]
sn-PA / FBpp0071057 [FlyBase]
Description(s) found:
Found 55 descriptions.
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  • The gene singed is referred to in FlyBase by the symbol Dmel\sn (CG32858, FBgn0003447). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7858057..7880118. It has the cytological map location 7D1-7D2. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: anatomical structure development; actin filament-based process; organelle organization; organ development; organ morphogenesis; cell projection organization; cell morphogenesis; wound healing; microvillar actin bundle formation; cytoskeleton organization. 210 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; female germline cyst; peripheral nervous system; nervous system; egg; adult segment; cuticle; sensillum; wing hair; antennal segment. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • The gene singed is referred to in FlyBase by the symbol Dmel\sn (CG32858, FBgn0003447). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7858057..7880118. It has the cytological map location 7D1-7D2. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: anatomical structure development; actin filament-based process; organelle organization; organ development; organ morphogenesis; cell projection organization; cell morphogenesis; wound healing; microvillar actin bundle formation; cytoskeleton organization. 210 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; female germline cyst; peripheral nervous system; nervous system; egg; adult segment; cuticle; sensillum; wing hair; antennal segment. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • The gene singed is referred to in FlyBase by the symbol Dmel\sn (CG32858, FBgn0003447). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7858057..7880118. It has the cytological map location 7D1-7D2. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: anatomical structure development; actin filament-based process; organelle organization; organ development; organ morphogenesis; cell projection organization; cell morphogenesis; wound healing; microvillar actin bundle formation; cytoskeleton organization. 210 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; female germline cyst; peripheral nervous system; nervous system; egg; adult segment; cuticle; sensillum; wing hair; antennal segment. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
  • The gene singed is referred to in FlyBase by the symbol Dmel\sn (CG32858, FBgn0003447). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7858057..7880118. It has the cytological map location 7D1-7D2. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: anatomical structure development; actin filament-based process; organelle organization; organ development; organ morphogenesis; cell projection organization; cell morphogenesis; wound healing; microvillar actin bundle formation; cytoskeleton organization. 210 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; female germline cyst; peripheral nervous system; nervous system; egg; adult segment; cuticle; sensillum; wing hair; antennal segment. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 512 amino acids

    Gene Ontology:
    Cellular Component: actin cytoskeleton [IDA]
    filamentous actin [IDA]
    Biological Process: hemocyte migration [IMP]
    establishment or maintenance of cell polarity [IMP]
    neuron projection morphogenesis [IMP]
    actin filament organization [TAS]
    antennal morphogenesis [IMP]
    bristle morphogenesis [IMP][NAS]
    wound healing [IMP]
    epidermal cell differentiation [IMP]
    oogenesis [NAS][TAS]
    imaginal disc-derived wing hair organization [IMP]
    microvillar actin bundle assembly [IMP]
    actin cytoskeleton organization [IMP]
    actin filament bundle assembly [IMP][NAS]
    cuticle pattern formation [IMP]
    Molecular Function: actin filament binding [IEA]
    actin binding [ISS]
    protein binding, bridging [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGQGCELGH SNGDIISQNQ QKGWWTIGLI NGQHKYMTAE TFGFKLNANG ASLKKKQLWT  60
   61 LEPSNTGESI IYLRSHLNKY LSVDQFGNVL CESDERDAGS RFQISISEDG SGRWALKNES 120
  121 RGYFLGGTPD KLVCTAKTPG ASEFWTVHLA ARPQVNLRSI GRKRFAHLSE SQDEIHVDAN 180
  181 IPWGEDTLFT LEFRAEEGGR YALHTCNNKY LNANGKLQVV CNEDCLFSAE YHGGHLALRD 240
  241 RQGQYLSPIG SKAVLKSRSS SVTRDELFSL EDSLPQASFI AGLNLRYVSV KQGVDVTANQ 300
  301 DEVGENETFQ LEYDWSAHRW ALRTTQDRYW CLSAGGGIQA TGNRRCADAL FELIWHGDGS 360
  361 LSFRANNGKF LATKRSGHLF ATSESIEEIA KFYFYLINRP ILVLKCEQGF VGYRTPGNLK 420
  421 LECNKATYET ILVERAQKGL VHLKAHSGKY WRIEGESISV DADAPSDGFF LELREPTRIC 480
  481 IRSQQGKYLG ATKNGAFKLL DDGTDSATQW EF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..512] PSI-BLAST 178.0 Fascin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle