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Protein Overview: FBpp0309148, p115-PA

General Information:
Name(s) found: FBpp0309148 [FlyBase]
p115-PA / FBpp0071045 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=X:7788160..7790670; ID=FBpp0309148; name=p115-PB; parent=FBgn0040087,FBtr0340162; dbxref=FlyBase:FBpp0309148,FlyBase_Annotation_IDs:CG1422-PB; MD5=b9b4846f5e7b9f1620128b86fefb7e2d; length=836; release=r5.56; species=Dmel; [FlyBase]
  • The gene p115 is referred to in FlyBase by the symbol Dmel\p115 (CG1422, FBgn0040087). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7788070..7790819. It has the cytological map location 7C2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding; protein transporter activity. There is experimental evidence that it is involved in the biological process</span>: Golgi organization. 6 alleles are reported. The phenotypes of these alleles are annotated with: Golgi stack; endoplasmic reticulum. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 836 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDA]
    Golgi membrane [IEA]
    Golgi stack [IDA]
    Biological Process: Golgi organization [IMP]
    vesicle docking during exocytosis [ISS]
    intracellular protein transport [IEA]
    vesicle fusion with Golgi apparatus [IEA]
    Molecular Function: protein transporter activity [IEA]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFLKSGIKT VLGSTEPGQQ PSAAETVEKL VDRVYSSTLL EDRRDACRAL KALSRKYRIE  60
   61 VGAQGMPPLV QVLQNDGQDA EIISYALDTL CNVVTSEEFD EEADNPTVSV NVGEQFTEMF 120
  121 IKTPEHVTLV MGYLDEYDFR VRRAAIQLIT SLISNKTREL QDLILVSPMG VSKLMDLLTD 180
  181 SREVIRNDVL LLLIELTKGN SNIQKIVAFE NAFDRLFEIV REEGCSDGGI VVEDCLILLL 240
  241 NLLKNNSSNQ QFFKEGSYIQ RLSPMFELSQ DAEEVGWSPQ KVSNFHCLLQ VVRALVTPSN 300
  301 QQQVVAACQR VMQKSRLLHA LCEILMSSGV PADILTETIN AVAEVVRGDR DNQDELGRVM 360
  361 APSSPPRPAI VVLLMSMINE KQLLALRCAV LYCFECFLYR NADGQRAVVQ TLLPSSASDV 420
  421 SALSTGQLLC TGLFSTDALA NWFSAVALMH SLVENVALKE ELLRVLLATP GGQKPITLLE 480
  481 QCTNLMQQER YRLQSKVGLL MLLSLWLAHC PGAVKALLET QGTMAYLTAQ LCSNEHDERE 540
  541 FLVQGMCAFL MGLCIQFNDN SLPGQKREDI SQLIIKRIGQ ESFCSKLAEV SRHEAYSRAC 600
  601 KQAQIRAKSA GELLLDFEYC KLYKGLEALI AKLVSGFDVD GIELTELTLS SEASALVSQY 660
  661 KGIIRGMDAQ IQALQQSSKE LEQENAELKE KLGEEQSLKA QLLDQNTLLK AQLGASTGQV 720
  721 QSAQGAEATP PNEEELNAAR YQANMYFAEN IRLTKELETL RQQLSAEKQS ADAAQDSLAA 780
  781 MQKDQEDLLE LLADQEAKLT RYEEAGSTNT LPTSNVAPSV PAAGGGSPIP SGTASR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..464] FFAS03 3.97 Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
    2 View Details [465..836] PSI-BLAST 39.221849 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.38363524631144 bayes_pls_golite062009
  • clathrin binding
    		•  2.23233599894789 bayes_pls_golite062009
  • protein transporter activity
    		•  1.84250643947717 bayes_pls_golite062009
  • protein binding
    		•  1.81870125631028 bayes_pls_golite062009
  • transporter activity
    		•  1.12250209220616 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.68280791022469 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.142369414135278 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle