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Protein Overview: dec-1-PB

General Information:
Name(s) found: dec-1-PB / FBpp0071098 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene defective chorion 1 is referred to in FlyBase by the symbol Dmel\dec-1 (CG2175, FBgn0000427). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7761229..7767255. It has the cytological map location 7C1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: structural constituent of chorion. There is experimental evidence that it is involved in the biological process</span>: chorion-containing eggshell formation. 53 alleles are reported. The phenotypes of these alleles are annotated with: vitelline membrane; chorion; egg; dorsal appendage; endochorion. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1208 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IDA]
    chorion [IEA]
    Biological Process: eggshell chorion assembly [NAS][TAS]
    chorion-containing eggshell formation [IMP][TAS]
    Molecular Function: structural constituent of chorion [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLFSLLPLL ALLVVQAAGQ SEVTSDDPAT DAGSTTNSTT DTKPRIPSQD EILGQMPSIN  60
   61 PIRTGNPQMD AFYMMFPALG SLLKWGSLFP AYSILGAIPD NLQPTAAASK VVLVLADDAT 120
  121 AKTRVARQNP PPNPLGQLMN WPALPQDFQL PSMDLGPQVG SFLAQLPAMP TVPGLLGAAA 180
  181 PVPAPAPAPA AAPPPAPAPA ADPPAAPVPD APQPAILGQA ALQNAFTFFN PANFDASSLL 240
  241 GQSVPTFAPP NLDFVAQMQR QFFPGMTPAQ PAAAGTDAQA SDISEVRVRP EDPYSQEAQM 300
  301 KIKSALEMEQ ERQQQAQVKD QEQVPLLWFR MPTTQNQDAT EEKTLEDLRV EAKLRAFERQ 360
  361 VIAELRMLQK IELMAKQMRS SAAAQNGDSP YRISYPLSRT PIHKITRADI EQALRDDYVR 420
  421 RLVNKEAQRR ARNSGINTQK ANALKRQAKS QDQTLSKEDI VQIMAYAYRM ANEQMESEKG 480
  481 KQDKVYAAYR TEQNPMMMQQ RQWSEEQAKI QQNQQQIQQN PMMMQQRQWS EEQAKIQQNQ 540
  541 QQIQQNPMMM QQRQWSEEQA KIQQNQQQIQ QNPMMMQQRQ WSEEQAKIQQ NQQQIQQNPM 600
  601 MVQQRQWSEE QAKIQQNQQQ IQQNPMMMQQ RQWSEEQAKI QHDQQMAQQM AQQGLMMTEQ 660
  661 RQRQWSEDQA KIQQAQQMAQ QTPMMMPQMQ QRQWTEDPQM VQQMQQRQWA EDQTRMQMAQ 720
  721 QNPMMQQQRQ MAENPQMMQQ RQWSEEQTKI EQAQQMAQQN QMMMQQMQQR QWSEDQAQIQ 780
  781 QQQRQMMQQT PMMMKERQWA EENPQSVQQQ GPMMMQQQMP SMMQREVEDE DNKAEDDLVG 840
  841 EAGPQMPENE GTARHKVDAL GVGGNKRKKS KSKSAPPTVI NYYYAAPQRP VVQSYGTSYG 900
  901 GGGYGSNAYG VPRPVNSYQS QGYRAAVGND EVDEMLRQHQ TMARTINPKQ PGEVGGSESQ 960
  961 KSNSNPPTTL TPAPQEQPQE HRVHKSPSSA PSETEIENAP SSDPQVGSIF TYGEGLLHPF1020
 1021 MGLLPVERPD DPWNQKPYDP HHPLYTGGGS YDAYLRDGRH RRDTHIMGQG TQHGILTPGM1080
 1081 LERLLRIKMD FQRRFPHLYK GMLNHHTNLT RVEVQPPVLG KISKPKTKTK PKNEDEPVFE1140
 1141 LGAAERSLFE DETNDSLEKD PEPEPDEEDD RDVEEPSESS EPRGFSSKKS RDENDIDYFN1200
 1201 FDDDDVDD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..116] FFAS03 0.963 Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
    2 View Details [117..208] MSA 2.304991 View MSA. No confident structure predictions are available.
    3 View Details [209..565] PSI-BLAST 31.0 Heavy meromyosin subfragment
    4 View Details [566..838] FFAS03 1.48 No description for 2i1jA was found.
    5 View Details [839..918] FFAS03 1.18 No description for 2fj7I was found.
    6 View Details [919..1208] PSI-BLAST 5.69897 Tropomyosin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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