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Protein Overview: NELF-B-PA

General Information:
Name(s) found: NELF-B-PA / FBpp0071034 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene NELF-B is referred to in FlyBase by the symbol Dmel\NELF-B (CG32721, FBgn0027553). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:7620027..7622355. It has the cytological map location 7B7. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: negative regulation of transcription from RNA polymerase II promoter, mitotic. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 594 amino acids

    Gene Ontology:
    Cellular Component: transcriptional repressor complex [ISS]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter, mitotic [ISS]
    negative regulation of transcription [IEA]
    Molecular Function: mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIMSTPAKNN NGTGLEDVNI PGQAYLREAL TSCTDPLKAI ESFQLENGVL LPSLRPMLPL  60
   61 LDLHGVRRLD FHTSLMEELR DKLIAHINEM GQKEPRERDK KLKELLVKSF PVVRVKSLRP 120
  121 VVMAILRNTQ HIDDKYLKIL VRDRELYADT DTEVKRQIWR DNQSLFGDEV SPLLSQYIRE 180
  181 KEHILFDHTN LNNLFFHPTP KVRRQGEVVQ KLANMIGTSV KLYDMVLQFL RTLFLRTRNV 240
  241 HYCTLRAELL MALHDLEVQE IISIDPCHKF TWCLDACIRE KNVDIKRSRE LQGFLDNIKR 300
  301 GQEQVLGDLS MTLCDPYAIN FLATSAIKIL HHLINNEGMP RDNQILILLL RMLALGLSAW 360
  361 VMIDSQDFKE PKLDCQVVTK FLPALMSLMV DDQCRSLHAK LPPDERESAL TTIEHSGPAP 420
  421 DAVEAYIQES SVASILAMYY TLHTARLKDR VGVLRVLAIL SACKDDRAYE DPFLHSLIAL 480
  481 LIPMSEEFAT EDFCTTLFDE FIFAGLTREN VTSRHMLKLL WYVHNKLPAG RLATLMKAMQ 540
  541 PTTAHNEHIH KLYEILQERI GTGAAETPVI EAPPMEFDSP LKSVPTPGPH YNVQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..99] MSA 1.013982 View MSA. No confident structure predictions are available.
    2 View Details [100..229] deduced N/A No confident structure predictions are available.
    3 View Details [230..393] deduced N/A No confident structure predictions are available.
    4 View Details [394..594] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle