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Protein Overview: inx7-PA

General Information:
Name(s) found: inx7-PA / FBpp0070994 [FlyBase]
Description(s) found:
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  • gi|7290783|gb|AAF46228.1| innexin 7, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|5739204|gb|AAD50379.1| gap junction protein prp7 [Drosophila melanogaster] [NCBI NR]
  • gi|28571416|ref|NP_788872.1| innexin 7, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|255653104|gb|ACU24750.1| RE24850p [Drosophila melanogaster] [NCBI NR]
  • gi|10720055|sp|Q9V3W6.1|INX7_DROME RecName: Full=Innexin inx7; Short=Innexin-7; AltName: Full=Gap junction protein prp7; AltName: Full=Pas-related protein 7 [NCBI NR]
  • Innexin inx7 OS=Drosophila melanogaster GN=Inx7 PE=2 SV=1 [Swiss-Prot]
  • The gene innexin 7 is referred to in FlyBase by the symbol Dmel\inx7 (CG2977, FBgn0027106). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6885645..6903902. It has the cytological map location 6E4. Based on sequence similarity, it is predicted to have molecular function</span>: gap junction channel activity. The biological processes in which it is involved are not known. 32 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG2977-PA translation from_gene[CG2977 inx7 FBgn0027106] seq_release:3 mol_weight=50670 cds_boundaries:(X:6,732,109..6,733,789[-]) aa_length:438 transcript_info:[CG2977-RA seq_release:3] gene_info:[gene symbol:inx7 synonyms:[CG32731] FBgn0027106 gene_ [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V3W6) Innexin Inx7 (Innexin-7) (Gap junction protein prp7) (Pas-related protein 7) [DrosMelano7227.FASTAC.txt]
  • (AE003439) inx6 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG2977-PA, isoform A [Drosophila melanogaster]gi|28571416|ref|NP_788872.1| CG2977-PA [Drosophila melanogaster]gi|5739204|gb|AAD50379.1| gap junction protein prp7 [Drosophila melanogaster]gi|10720055|sp|Q9V3W6|INX7_DROME Innexin Inx7 (Innexin-7) (Gap ju [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:complement(6885763..6886135,6886206..6886915,6887213..6887446); ID=FBpp0070994; name=inx7-PA; parent=FBgn0027106,FBtr0071035; dbxref=FlyBase:FBpp0070994,FlyBase_Annotation_IDs:CG2977-PA,GB_protein:AAF46228.1,REFSEQ:NP_788872,GB_protein [fly-100309-contam.fasta]
  • gap junction protein prp7 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • innexin 7 CG2977-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Innexin inx7 (Innexin-7) (Gap junction protein prp7) (Pas-related protein 7) [nr-271106-contam.fasta]
  • CG2977-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:complement(6885763..6886135,6886206..6886915,6887213..6887446); ID=FBpp0070994; name=inx7-PA; parent=FBgn0027106,FBtr0071035; dbxref=FlyBase:FBpp0070994,FlyBase_Annotation_IDs:CG2977-PA,GB_protein:AAF46228.1,REFSEQ:NP_788872,GB_protein:AAF46228; MD5=6d350bde71f891481cb073ab23b032b2; length=438; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:complement(6885763..6886135,6886206..6886915,6887213..6887446); ID=FBpp0070994; name=inx7-PA; parent=FBgn0027106,FBtr0071035; dbxref=FlyBase:FBpp0070994,FlyBase_Annotation_IDs:CG2977-PA,GB_protein:AAF46228.1,REFSEQ:NP_788872,GB_protein:AAF46228; MD5=6d350bde71f891481cb073ab23b032b2; length=438; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Innexin inx7 OS=Drosophila melanogaster GN=inx7 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • RE24850p OS=Drosophila melanogaster GN=inx7-RA PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:complement(6885763..6886135,6886206..6886915,6887213..6887446); ID=FBpp0070994; name=inx7-PA; parent=FBgn0027106,FBtr0071035; dbxref=FlyBase:FBpp0070994,FlyBase_Annotation_IDs:CG2977-PA,GB_protein:AAF46228.1,REFSEQ:NP_788872,GB_protein:AAF46228,FlyMine:FBpp0070994,modMine:FBpp0070994; MD5=6d350bde71f891481cb073ab23b032b2; length=438; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:complement(join(6993180..6993413,6992173..6992882,6991730..6992102)); ID=FBpp0070994; name=Inx7-PA; parent=FBgn0027106,FBtr0071035; dbxref=FlyBase:FBpp0070994,FlyBase_Annotation_IDs:CG2977-PA,GB_protein:AAF46228.1,REFSEQ:NP_788872,GB_protein:AAF46228,FlyMine:FBpp0070994,modMine:FBpp0070994; MD5=6d350bde71f891481cb073ab23b032b2; length=438; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:complement(join(6993180..6993413,6992173..6992882,6991730..6992102)); ID=FBpp0070994; name=Inx7-PA; parent=FBgn0027106,FBtr0071035; dbxref=FlyBase:FBpp0070994,FlyBase_Annotation_IDs:CG2977-PA,GB_protein:AAF46228.1,REFSEQ:NP_788872,GB_protein:AAF46228,FlyMine:FBpp0070994,modMine:FBpp0070994; MD5=6d350bde71f891481cb073ab23b032b2; length=438; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0070994 type=protein; loc=X:complement(join(6993180..6993413,6992173..6992882,6991730..6992102)); ID=FBpp0070994; name=Inx7-PA; parent=FBgn0027106,FBtr0071035; dbxref=FlyBase:FBpp0070994,FlyBase_Annotation_IDs:CG2977-PA,GB_protein:AAF46228.1,REFSEQ:NP_788872,GB_protein:AAF46228,FlyMine:FBpp0070994,modMine:FBpp0070994; MD5=6d350bde71f891481cb073ab23b032b2; length=438; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:complement(join(6993180..6993413,6992173..6992882,6991730..6992102)); ID=FBpp0070994; name=Inx7-PA; parent=FBgn0027106,FBtr0071035; dbxref=FlyBase:FBpp0070994,FlyBase_Annotation_IDs:CG2977-PA,GB_protein:AAF46228.1,REFSEQ:NP_788872,GB_protein:AAF46228,UniProt/Swiss-Prot:Q9V3W6,FlyMine:FBpp0070994,modMine:FBpp0070994; MD5=6d350bde71f891481cb073ab23b032b2; length=438; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 438 amino acids

    Gene Ontology:
    Cellular Component: gap junction [IDA][ISS][NAS]
    integral to membrane [NAS]
    Biological Process: NONE FOUND
    Molecular Function: gap junction channel activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNTFSSVRQ YLKFDLTRVV IDNIVFKLHY RWTFVILLVA TLLITSRQYI GEHIQCLSDG  60
   61 VVSPVINTFC FFTPTFTVVR DQNQTAYRPG SEPPGIGAFD PEKDTIKRHA YYQWVPFVLF 120
  121 FQALCFYIPH ALWKSWEGGR IKALVFGLRM VGLTRYLKND SLRIGKLNIP SMAEAEERVK 180
  181 DIRRTMIDRM RLNQSWGAHL VFAEVLNLIN LLLQITWTNR FLGGQFLTLG PHALKNRWSD 240
  241 ELSVLDLVFP KITKCKFHKF GDSGSIQMHD ALCVMALNIM NEKIYIILWF WYAFLLIVTV 300
  301 LGLLWRILTL CFYRNVTFTR WSLYWAKPGQ LDENELLAVI DKCNFSNWMF LFFLRSNLSE 360
  361 FLFKKVIYHL ASEFPNPDHD NDVNAYREAP PTPAKNRYPE LSGLDTIDSP LLHLRRNGSP 420
  421 SAGGAQGPST SDMAKLPV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..137] MSA 7.124983 View MSA. No confident structure predictions are available.
    2 View Details [138..223] deduced N/A No confident structure predictions are available.
    3 View Details [224..330] MSA 3.123996 View MSA. No confident structure predictions are available.
    4 View Details [331..438] MSA 1.103994 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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