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Protein Overview: CG5937-PA

General Information:
Name(s) found: CG5937-PA / FBpp0070833 [FlyBase]
Description(s) found:
Found 11 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG5937 (CG5937, FBgn0029834). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5934735..5942543. It has the cytological map location 5D2-5D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ARF guanyl-nucleotide exchange factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of ARF protein signal transduction. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2016 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: regulation of ARF protein signal transduction [IEA]
    Molecular Function: ARF guanyl-nucleotide exchange factor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALDTKRPKF ITMGLNGLHR VIKDERFYIG LEPEDDSVWL PSQLLRATNG ILPTTSSEDT  60
   61 VVNVLRLFLA MACSPACTLN GRLLIEILSR CGECWEMGSR ATKAASLAAA SQCLRTFCAF 120
  121 LIEEAEEVKK TAPAGLMTQT QASAVYNEVI PVMQWLCSRL VEPNVNASPN KKCENHSSLY 180
  181 LTECILTLSS ALPRNVHANP HFTSFLWQKF CPTLAAALGS PGRINLDKKF TYKLVKGNKN 240
  241 KNIESPNIHY LRDALHMIEN EARGFFTGPG LDGPQARCVY LTAIQLLRIA GAHGSLRPML 300
  301 EALFHRMLLL PAPQNRTEPL RCVREIFKSP ERLIDLAVIL YVDKNTAQGC SDEMALFRLL 360
  361 VDAMEECAYG ASGGGSATEA SLQASVECMV ALLDSLQVLC SGELTESMIS DQIVQVVNGR 420
  421 HDLLKDADYS GPLTYQSMAR LPAPYRDAIV EFRQTVFETS SGSESEGEPQ HEQDAASNGS 480
  481 GDTEGPEDDD PSSSSDETSR VENRWPYSHL EAPVMPIRTD SDNDRQHARD FARALRQDLV 540
  541 PKLLRLRSCV ELDEAMQEFA SAVCQENSMN FSDFDYNLTA INADGIYLAI YSSLLLSLQL 600
  601 MRAGFYEQVA QGMSHKDILV PMSEQQFVTS VQNTGVLVYL SSPWLCELYQ SVTVCNVLEA 660
  661 MPRQQLEGMG PRCALVDMLC DAGGLGATQM LSEWQRLQTA NVKHKEEEQL HDKRREAAKK 720
  721 LCRRLLTCCW DSMVIVLSSG LGDLQTSSAS NKLVALSKRT LRVKAKANKS NGEALYAMCL 780
  781 DGLHSAATLS NSLNLQHLAG KILNLLASNV CQTSGPRISA SQAMSMDVVL TGGLNLGSYS 840
  841 ADCWPSIFAV CRHVSQLEHE IFSMQNPAIS ASPGSSRRDL ETGEKLSNGN AQDKLNLSSI 900
  901 PIDDDETCVD VYSFLQAPMQ SPNTNITSIL KVYSGTNETV LLSQSDTSKV LCALSHQAEN 960
  961 LFGDAAERLS LPSLCQFLKH LCRASRDQLY KSQVARKGSR IWWPSKGWKK LDSLPMSLLL1020
 1021 HRIGDVTLKV FRSSRPLLHV LKVWAITGPH LMDAACHRDR MISKRAIEYI HDIITALLVE1080
 1081 QSELPYFHFN EALLKPFENL LSMDTDVDVQ DQIVACLYEV VEAHRTEIRS GWRPLFGTLR1140
 1141 NARSRMLNMS NIIDIFRVFL DSDNTLVFAN AGLDCILCLL SYLEISGGGN NNACSGGSGS1200
 1201 AAGGTASNGG QQEEDNTFRP TDFLHETLRF LERCSSILGF MHSMPKCPNF HSTYKIKGIS1260
 1261 YTHIIDANIP SSMENFTYFG NDYLQTRNEQ YMISYRSLHI DKDTIVKIDE MDKPSGVLKV1320
 1321 WFLLLDGLTN SLIVCPYSHQ APILQTIFKL FKNLLASPGI DFGFYCINHL LVPMIQDWLR1380
 1381 YINKTGSSWQ LVEKNFKHCC CMTTDLVVEF IEKSVPEQRR LGAGTKTRLA QIVHPADNLL1440
 1441 YSKLKFVTER IEREQQQQQS PSVQDHGCGY TQQYDSSSSS ASEEQQKNGG GVGGGGSNLI1500
 1501 ESPTKISGSA TLALKQLLLV LIECAAQSQE AIARISVSCL KHVILSTGML FNESQWMIAC1560
 1561 SAIHRACTVT IAPLRQLSFA FHEKSNSFYG DCANVKVAAR RDSSLEELAR IYALAQQVFL1620
 1621 SDNQREPGQN QAPTPSASQC KLSDDRSYSF LLYPLNNGFN SNLDNFVIRI PFKNLVVGLL1680
 1681 ANQMLLQLVA KLLLSRLKCV PQAVSTCIFD NYAASAASPS HDYDLDFRSK EILLRCVKQY1740
 1741 LMSALEFDSR PGLKFLMQKV SNIEYAANLY KQMTSSWMIY YIALVDSHLN DIVVYNLGPE1800
 1801 DLNFILESCS RLNTTTVKKK ENFVRYLFCL QDAWNLVCEL YLSNSALHEI ESGSGKLRQK1860
 1861 PPQLLHHPQT KPMCISLNGN GDAEMTDTGS GSGSGSSTSP SKCVQLQEEE NVTMTTLISE1920
 1921 FQPKCRSNPF DTNRQAKSSE AESISPEIEQ QRASSILKDS NYKRAALAQL VVASMELLRS1980
 1981 LPGEAEENLK LLMTPTIREA FRLVQLQGNE LKVNQF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] MSA 6.124985 View MSA. No confident structure predictions are available.
    2 View Details [130..223] deduced N/A No confident structure predictions are available.
    3 View Details [224..370] MSA 1.158975 View MSA. No confident structure predictions are available.
    4 View Details [371..747] PSI-BLAST 42.39794 The structure of RalF
    5 View Details [748..925] deduced N/A No confident structure predictions are available.
    6 View Details [926..1143] MSA 2.142972 View MSA. No confident structure predictions are available.
    7 View Details [1144..1219] deduced N/A No confident structure predictions are available.
    8 View Details [1220..1381] MSA 2.110985 View MSA. No confident structure predictions are available.
    9 View Details [1382..1484] deduced N/A No confident structure predictions are available.
    10 View Details [1485..1673] deduced N/A No confident structure predictions are available.
    11 View Details [1674..1885] MSA 2.028988 View MSA. No confident structure predictions are available.
    12 View Details [1886..2016] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • enzyme regulator activity
    		•  0.33175950121636 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.31803821430449 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.31764113391724 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.19174216196088 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.
    11 No functions predicted.
    12 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle