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View Structure Prediction Details

Protein: CG5937-PA
Organism: Drosophila melanogaster
Length: 2016 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5937-PA.

Description E-value Query
Range
Subject
Range
gi|54643155, gi|... - gi|54643155|gb|EAL31899.1| GA19244-PA [Drosophila pseudoobscura], gi|125981681|ref|XP_001354844.1| G...
1460.0 [0..1] [2016..27]

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Predicted Domain #1
Region A:
Residues: [1-129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALDTKRPKF ITMGLNGLHR VIKDERFYIG LEPEDDSVWL PSQLLRATNG ILPTTSSEDT  60
   61 VVNVLRLFLA MACSPACTLN GRLLIEILSR CGECWEMGSR ATKAASLAAA SQCLRTFCAF 120
  121 LIEEAEEVK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [130-223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTAPAGLMTQ TQASAVYNEV IPVMQWLCSR LVEPNVNASP NKKCENHSSL YLTECILTLS  60
   61 SALPRNVHAN PHFTSFLWQK FCPTLAAALG SPGR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [224-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INLDKKFTYK LVKGNKNKNI ESPNIHYLRD ALHMIENEAR GFFTGPGLDG PQARCVYLTA  60
   61 IQLLRIAGAH GSLRPMLEAL FHRMLLLPAP QNRTEPLRCV REIFKSPERL IDLAVILYVD 120
  121 KNTAQGCSDE MALFRLLVDA MEECAYG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [371-747]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASGGGSATEA SLQASVECMV ALLDSLQVLC SGELTESMIS DQIVQVVNGR HDLLKDADYS  60
   61 GPLTYQSMAR LPAPYRDAIV EFRQTVFETS SGSESEGEPQ HEQDAASNGS GDTEGPEDDD 120
  121 PSSSSDETSR VENRWPYSHL EAPVMPIRTD SDNDRQHARD FARALRQDLV PKLLRLRSCV 180
  181 ELDEAMQEFA SAVCQENSMN FSDFDYNLTA INADGIYLAI YSSLLLSLQL MRAGFYEQVA 240
  241 QGMSHKDILV PMSEQQFVTS VQNTGVLVYL SSPWLCELYQ SVTVCNVLEA MPRQQLEGMG 300
  301 PRCALVDMLC DAGGLGATQM LSEWQRLQTA NVKHKEEEQL HDKRREAAKK LCRRLLTCCW 360
  361 DSMVIVLSSG LGDLQTS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.39794
Match: 1xszA
Description: The structure of RalF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
enzyme regulator activity 0.33175950121636 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.31803821430449 bayes_pls_golite062009
GTPase regulator activity 0.31764113391724 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.19174216196088 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [748-925]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASNKLVALS KRTLRVKAKA NKSNGEALYA MCLDGLHSAA TLSNSLNLQH LAGKILNLLA  60
   61 SNVCQTSGPR ISASQAMSMD VVLTGGLNLG SYSADCWPSI FAVCRHVSQL EHEIFSMQNP 120
  121 AISASPGSSR RDLETGEKLS NGNAQDKLNL SSIPIDDDET CVDVYSFLQA PMQSPNTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [926-1143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITSILKVYSG TNETVLLSQS DTSKVLCALS HQAENLFGDA AERLSLPSLC QFLKHLCRAS  60
   61 RDQLYKSQVA RKGSRIWWPS KGWKKLDSLP MSLLLHRIGD VTLKVFRSSR PLLHVLKVWA 120
  121 ITGPHLMDAA CHRDRMISKR AIEYIHDIIT ALLVEQSELP YFHFNEALLK PFENLLSMDT 180
  181 DVDVQDQIVA CLYEVVEAHR TEIRSGWRPL FGTLRNAR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1144-1219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRMLNMSNII DIFRVFLDSD NTLVFANAGL DCILCLLSYL EISGGGNNNA CSGGSGSAAG  60
   61 GTASNGGQQE EDNTFR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1220-1381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTDFLHETLR FLERCSSILG FMHSMPKCPN FHSTYKIKGI SYTHIIDANI PSSMENFTYF  60
   61 GNDYLQTRNE QYMISYRSLH IDKDTIVKID EMDKPSGVLK VWFLLLDGLT NSLIVCPYSH 120
  121 QAPILQTIFK LFKNLLASPG IDFGFYCINH LLVPMIQDWL RY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1382-1484]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INKTGSSWQL VEKNFKHCCC MTTDLVVEFI EKSVPEQRRL GAGTKTRLAQ IVHPADNLLY  60
   61 SKLKFVTERI EREQQQQQSP SVQDHGCGYT QQYDSSSSSA SEE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1485-1673]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQKNGGGVGG GGSNLIESPT KISGSATLAL KQLLLVLIEC AAQSQEAIAR ISVSCLKHVI  60
   61 LSTGMLFNES QWMIACSAIH RACTVTIAPL RQLSFAFHEK SNSFYGDCAN VKVAARRDSS 120
  121 LEELARIYAL AQQVFLSDNQ REPGQNQAPT PSASQCKLSD DRSYSFLLYP LNNGFNSNLD 180
  181 NFVIRIPFK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1674-1885]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLVVGLLANQ MLLQLVAKLL LSRLKCVPQA VSTCIFDNYA ASAASPSHDY DLDFRSKEIL  60
   61 LRCVKQYLMS ALEFDSRPGL KFLMQKVSNI EYAANLYKQM TSSWMIYYIA LVDSHLNDIV 120
  121 VYNLGPEDLN FILESCSRLN TTTVKKKENF VRYLFCLQDA WNLVCELYLS NSALHEIESG 180
  181 SGKLRQKPPQ LLHHPQTKPM CISLNGNGDA EM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1886-2016]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDTGSGSGSG SSTSPSKCVQ LQEEENVTMT TLISEFQPKC RSNPFDTNRQ AKSSEAESIS  60
   61 PEIEQQRASS ILKDSNYKRA ALAQLVVASM ELLRSLPGEA EENLKLLMTP TIREAFRLVQ 120
  121 LQGNELKVNQ F

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle