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Protein Overview: CG6927-PA

General Information:
Name(s) found: CG6927-PA / FBpp0070689 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG6927 (CG6927, FBgn0029733). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:4800945..4802854. It has the cytological map location 4D5. Based on sequence similarity, it is predicted to have molecular function</span>: extracellular-glycine-gated chloride channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ion transport. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 524 amino acids

    Gene Ontology:
    Cellular Component: glycine-gated chloride channel complex [ISS]
    postsynaptic membrane [IEA]
    Biological Process: ion transport [IEA]
    Molecular Function: extracellular-glycine-gated chloride channel activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEWSLIISIL LNCLYASASA LDEDCPTLDD GDSLSQTQLL DRLTHGCRYD RLERPITYSE  60
   61 TGQRLPVDVY MRAYIYFMQN LEAHDLQFKI YALLQMRYLD PRLNFRNVSP KRRQPILGEE 120
  121 HLRNSLWMPH IFLANERDSS ILGLTEKDIL TSISPDGTVI VSNRIKATLY CWLNLKKFPF 180
  181 DEQHCSTVLE SWMYNTSELV LHWEQKRPIT YDGALHLTEF VLQRSWSNET VINADLSDLR 240
  241 HGAFAGNYSS LSFTVHLTRV VGFYLMDYFL PSMLIVAISW VSFWLQADQA PPRITLGTST 300
  301 LLTFITLASA QGKTLPKVSY IKVSEVWFLG CTIFIFGSMV EFAFVNTIWR RKKSVPVKKL 360
  361 NSKHILKSTL SPNLLRRRSH ARSRSFSGTA LHKTADTGSL GGAGFNNYLT VNLPITTIKE 420
  421 GQVLDQQRTS RVVQKMDVNF VESAFGSMGS AQSTGAISAA SSSQTLTNNN RTESAGHQEE 480
  481 IDLSGWTTLT PQEIAMWIDS RARFVFPLSF LVFNLFFWTF VYCI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..370] PSI-BLAST 69.522879 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    2 View Details [371..524] PSI-BLAST 37.09691 Acetylcholine receptor protein, beta chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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