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Protein Overview: FBpp0305388, Tip...

General Information:
Name(s) found: FBpp0305388 [FlyBase]
Tip60-PA / FBpp0070636 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • type=protein; loc=X:complement(4008962..4008962,4009035..4009247,4009353..4010577,4010632..4010758,4010826..4010885); ID=FBpp0305388; name=Tip60-PC; parent=FBgn0026080,FBtr0333186; dbxref=REFSEQ:NP_001259234,GB_protein:AGB95080,FlyBase:FBpp0305388,FlyBase_Annotation_IDs:CG6121-PC; MD5=c269603952226ebf2f9f3f7fad06bcd7; length=541; release=r5.56; species=Dmel; [FlyBase]
  • The gene Tip60 is referred to in FlyBase by the symbol Dmel\Tip60 (CG6121, FBgn0026080). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:4008833..4011475. It has the cytological map location 4A6-4B1. Based on sequence similarity, it is predicted to have molecular function</span>: histone acetyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus. 10 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 541 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    chromatin [IEA]
    Biological Process: chromatin assembly or disassembly [IEA]
    regulation of transcription [IEA]
    response to DNA damage stimulus [IMP]
    Molecular Function: histone acetyltransferase activity [ISS]
    chromatin binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKINHKYEFD DDVASICEST AALTEGCRLP VRMHKTDDWP LAEIVSIKEL DGRRQFYVHY  60
   61 VDFNKRLDEW VNEEDLYTRK VQFPRRDGSQ TGTSTGVTTP QRHHSLAGSV SRPTSPQHPG 120
  121 SGALAAIPQT PTGASGSVPP PAGIPNSVAP PGTPSSGGEL VNGNNLAAAL QKRINRKRKN 180
  181 HGGSAHGHHS LTSQQQQSHP HPTTPQTPTA TPVHVTGDGL ISGAANDDGD GSQDGKTPTP 240
  241 RQSGSMVTHQ DDVVTRMKNV EMIELGRHRI KPWYFSPYPQ ELCQMPCIYI CEFCLKYRKS 300
  301 RKCLERHLSK CNLRHPPGNE IYRKHTISFF EIDGRKNKVY AQNLCLLAKL FLDHKTLYYD 360
  361 TDPFLFYVMT EFDSRGFHIV GYFSKEKEST EDYNVACILT MPPYQRKGYG KLLIEFSYEL 420
  421 SKFEGKTGSP EKPLSDLGLL SYRSYWAQTI LEIFISQNPS TDGEKPTITI NDICECTSIK 480
  481 KEDVISTLQN LNLINYYKGQ YIVCINRVII EQHRRAMDKR KIRIDSKCLH WTPKDWSKRS 540
  541 K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] PSI-BLAST 8.39794 No description for 2ekoA was found.
    2 View Details [148..236] deduced N/A No confident structure predictions are available.
    3 View Details [237..541] PSI-BLAST 111.0 No description for 2ou2A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle