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Protein Overview: FBpp0309962, CG6...

General Information:
Name(s) found: FBpp0309962 [FlyBase]
CG6379-PA / FBpp0070639 [FlyBase]
Description(s) found:
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  • gi|7290461|gb|AAF45915.1| CG6379 [Drosophila melanogaster] [NCBI NR]
  • gi|24639619|ref|NP_572148.2| CG6379 [Drosophila melanogaster] [NCBI NR]
  • Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Drosophila melanogaster GN=CG6379 PE=2 SV=1 [Swiss-Prot]
  • type=protein; loc=X:complement(3992207..3993924,3994026..3994674); ID=FBpp0309962; name=CG6379-PB; parent=FBgn0029693,FBtr0343297; dbxref=FlyBase:FBpp0309962,FlyBase_Annotation_IDs:CG6379-PB; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG6379 (CG6379, FBgn0029693). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3991948..3995068. It has the cytological map location 4A5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: methyltransferase activity; nucleic acid binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: methylation. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG6379-PA translation from_gene[CG6379 CG6379 FBgn0029693] seq_release:3 mol_weight=90557 cds_boundaries:(X:3,838,793..3,841,257[-]) aa_length:788 transcript_info:[CG6379-RA seq_release:3] gene_info:[gene symbol:CG6379 FBgn0029693 gene_boundaries:(X:3 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W4N2) CG6379 protein [DrosMelano7227.FASTAC.txt]
  • (AE003430) CG6379 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG6379-PA [Drosophila melanogaster]gi|24639619|ref|NP_572148.2| CG6379-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:complement(3992207..3993924,3994026..3994674); ID=FBpp0070639; name=CG6379-PA; parent=FBgn0029693,FBtr0070671; dbxref=FlyBase:FBpp0070639,FlyBase_Annotation_IDs:CG6379-PA,GB_protein:AAF45915.1,REFSEQ:NP_572148,GB_protein:AAF45915; MD5= [fly-100309-contam.fasta]
  • CG6379-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:complement(3992207..3993924,3994026..3994674); ID=FBpp0070639; name=CG6379-PA; parent=FBgn0029693,FBtr0070671; dbxref=FlyBase:FBpp0070639,FlyBase_Annotation_IDs:CG6379-PA,GB_protein:AAF45915.1,REFSEQ:NP_572148,GB_protein:AAF45915; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:complement(3992207..3993924,3994026..3994674); ID=FBpp0070639; name=CG6379-PA; parent=FBgn0029693,FBtr0070671; dbxref=FlyBase:FBpp0070639,FlyBase_Annotation_IDs:CG6379-PA,GB_protein:AAF45915.1,REFSEQ:NP_572148,GB_protein:AAF45915; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=X:complement(3992207..3993924,3994026..3994674); ID=FBpp0070639; name=CG6379-PA; parent=FBgn0029693,FBtr0070671; dbxref=FlyBase:FBpp0070639,FlyBase_Annotation_IDs:CG6379-PA,GB_protein:AAF45915.1,REFSEQ:NP_572148,GB_protein:AAF45915,FlyMine:FBpp0070639,modMine:FBpp0070639; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:complement(join(4099993..4100641,4098174..4099891)); ID=FBpp0070639; name=CG6379-PA; parent=FBgn0029693,FBtr0070671; dbxref=FlyBase:FBpp0070639,FlyBase_Annotation_IDs:CG6379-PA,GB_protein:AAF45915.1,REFSEQ:NP_572148,GB_protein:AAF45915,FlyMine:FBpp0070639,modMine:FBpp0070639; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:complement(join(4099993..4100641,4098174..4099891)); ID=FBpp0309962; name=CG6379-PB; parent=FBgn0029693,FBtr0343297; dbxref=GB_protein:AHN59322,REFSEQ:NP_001284851,FlyBase:FBpp0309962,FlyBase_Annotation_IDs:CG6379-PB; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:complement(join(4099993..4100641,4098174..4099891)); ID=FBpp0070639; name=CG6379-PA; parent=FBgn0029693,FBtr0070671; dbxref=FlyBase:FBpp0070639,FlyBase_Annotation_IDs:CG6379-PA,GB_protein:AAF45915.1,REFSEQ:NP_572148,GB_protein:AAF45915,FlyMine:FBpp0070639,modMine:FBpp0070639; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=X:complement(join(4099993..4100641,4098174..4099891)); ID=FBpp0309962; name=CG6379-PB; parent=FBgn0029693,FBtr0343297; dbxref=GB_protein:AHN59322,REFSEQ:NP_001284851,FlyBase:FBpp0309962,FlyBase_Annotation_IDs:CG6379-PB; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9W4N2, CG6379, isoform B OS=Drosophila melanogaster GN=CG6379-RB PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0070639 type=protein; loc=X:complement(join(4099993..4100641,4098174..4099891)); ID=FBpp0070639; name=CG6379-PA; parent=FBgn0029693,FBtr0070671; dbxref=FlyBase:FBpp0070639,FlyBase_Annotation_IDs:CG6379-PA,GB_protein:AAF45915.1,REFSEQ:NP_572148,GB_protein:AAF45915,FlyMine:FBpp0070639,modMine:FBpp0070639; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0309962 type=protein; loc=X:complement(join(4099993..4100641,4098174..4099891)); ID=FBpp0309962; name=CG6379-PB; parent=FBgn0029693,FBtr0343297; dbxref=GB_protein:AHN59322,REFSEQ:NP_001284851,FlyBase:FBpp0309962,FlyBase_Annotation_IDs:CG6379-PB; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:complement(join(4099993..4100641,4098174..4099891)); ID=FBpp0070639; name=CG6379-PA; parent=FBgn0029693,FBtr0070671; dbxref=FlyBase:FBpp0070639,FlyBase_Annotation_IDs:CG6379-PA,GB_protein:AAF45915.1,REFSEQ:NP_572148,GB_protein:AAF45915,UniProt/Swiss-Prot:Q9W4N2,FlyMine:FBpp0070639,modMine:FBpp0070639; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=X:complement(join(4099993..4100641,4098174..4099891)); ID=FBpp0309962; name=CG6379-PB; parent=FBgn0029693,FBtr0343297; dbxref=GB_protein:AHN59322,REFSEQ:NP_001284851,FlyBase:FBpp0309962,FlyBase_Annotation_IDs:CG6379-PB,UniProt/Swiss-Prot:Q9W4N2; MD5=5f4fedad3d48a6ed73d29509cf0ca09b; length=788; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 788 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: methylation [IEA]
    Molecular Function: nucleic acid binding [IEA]
    methyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEPSDDENS EPTPKKIKRE WVKSYSNKAM EMMKKMGYEN DKGLGKSNQG RLEPIIAVQQ  60
   61 DGRRGFGLKL DTVQSSAGQW DPACEELEIP EPVLWLHNPG SRADAYSLDQ LMGHLVTGEK 120
  121 KLTLDGETRY CDPAILHHIL NAKTVFDDLN DNEKRRARSR CNPFETIRSS IFLNRAAVKM 180
  181 ANIDSMCNFM FTNPRDPAGQ TLVAPDELLY FTDMCAGPGG FSEYVLYRKS WEAKGFGFTL 240
  241 RGANDFKLEK FFAASPESFD TFYGVKEDGN IFDESNQDSL NEYIRMHTPQ GVHFAMADGG 300
  301 FSVEGQKNIQ EILSKQLYLC QFLTALKILR PNGSFVCKVF DLFTPFSVGL VYLMYKCFQQ 360
  361 IAIIKPNSSR PANSERYLVC KYKRSDAETA GIVAYLNTVN LMLSDESQLD ENDVLEIFNA 420
  421 NELAEDEDFL RYIIDSNNAI GKKQIVGLRK IAAFAQNLEL KETKQSEVRQ ECLKRWGLPD 480
  481 KLRQAPENKP TDRLLDELLA DWANERSWLS LPATEMKGVA SLNATIKNVA DWYFVPVGRE 540
  541 ETNINACSLF LCKSRGNLLR YTEHKKWELV ETAFEVQPRS IFFGQIVYEF YGEGRTIQRM 600
  601 AALHIIDGIC LGGVDIRRRP YRERVSMCDK FARSLNKPYR KDRTFGALRS KPLFRLQDMG 660
  661 SFFANMRHYV LKDNSQRLGF ALDDNKFFVP GGIMMFCELT NNYVSAHSRS RGQLYYFNVR 720
  721 NKESYYKDQI PRNKADEIFA SFRFSFSCRL LWKWTDLRQV EELATEDNPK ILFRSDFVKF 780
  781 IADKLGHS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] MSA 80.232997 View MSA. No confident structure predictions are available.
    2 View Details [149..385] PSI-BLAST 49.522879 RNA methyltransferase FtsJ
    3 View Details [386..537] MSA 1.228993 View MSA. No confident structure predictions are available.
    4 View Details [538..638] MSA 2.020975 View MSA. No confident structure predictions are available.
    5 View Details [639..788] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.857347609112816 bayes_pls_golite062009
  • transferase activity
    		•  0.769739415230943 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.648175251543522 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.646052703874729 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.00827854656426392 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle