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Protein Overview: CG8636-PA

General Information:
Name(s) found: CG8636-PA / FBpp0070430 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8636 (CG8636, FBgn0029629). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2503276..2504395. It has the cytological map location 3A7. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding; translation initiation factor activity. There is experimental evidence that it is involved in the biological process</span>: mitotic spindle elongation; mitotic spindle organization. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 269 amino acids

    Gene Ontology:
    Cellular Component: eukaryotic translation initiation factor 3 complex [ISS]
    Biological Process: mitotic spindle elongation [IMP]
    mitotic spindle organization [IMP]
    translational initiation [ISS]
    Molecular Function: nucleotide binding [IEA]
    nucleic acid binding [IEA]
    translation initiation factor activity [ISS]
    zinc ion binding [IEA]
    mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGVETIKSS WADEVELDYG GLPPTTETVE NGQKYVTEYK YNKDDKKTKV VRTYKISKQV  60
   61 VPKTVAKRRT WTKFGDSKND KPGPNSQTTM VSEEIIMQFL NSKEDEKAND PLLDPTKNIA 120
  121 KCRICNGEHW SVNCPYKGTA MDTNMMEKKA SAAAAAAVDA PKSGKYVPPF LKDSQKGALG 180
  181 MRGRDDTAAI RISNLSESMT EADLEELVKK IGPQSKMYLA RDKNTGLCKG FAYVHFKQRK 240
  241 DAAAAIEILN GHGYDHLILS VEWSKPQNN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..180] MSA 1.591994 View MSA. No confident structure predictions are available.
    2 View Details [181..269] PSI-BLAST 19.69897 solution structure of RNA binding domain in eukaryotic translation initiation factor 3 subunit 4


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle