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Protein Overview: tko-PB

General Information:
Name(s) found: tko-PB / FBpp0070443 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • The gene technical knockout is referred to in FlyBase by the symbol Dmel\tko (CG7925, FBgn0003714). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2336346..2338009. It has the cytological map location 3A3. Based on sequence similarity, it is predicted to have molecular function</span>: structural constituent of ribosome. There is experimental evidence that it is involved in the biological process</span>: response to mechanical stimulus; detection of mechanical stimulus involved in sensory perception of sound; male courtship behavior; mechanosensory behavior. 19 alleles are reported. The phenotypes of these alleles are annotated with: egg; macrochaeta. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 140 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial ribosome [NAS]
    mitochondrial small ribosomal subunit [ISS]
    Biological Process: mechanosensory behavior [IMP]
    sensory perception of sound [TAS]
    courtship behavior [TAS]
    male courtship behavior [IMP]
    detection of mechanical stimulus involved in sensory perception of sound [IMP]
    behavior [NAS]
    response to mechanical stimulus [IMP]
    translation [ISS]
    Molecular Function: structural constituent of ribosome [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFLRQSFGI TKQLASQAIQ CSYETAVRGM ASLQQMHRSG PHIKTRPPRQ PLDGKPFAKG  60
   61 VVLKTLIKKP KKPNSANRKC VLVRLSTGKE MVAYIPGIGH NLQEHNIVLC RVGRLQDVPG 120
  121 VKLKAVRGVY DLAHVVKKSQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] PSI-BLAST 44.69897 No description for 2f4vL was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle