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Protein Overview: FBpp0292966, FBp...

General Information:
Name(s) found: FBpp0305878 [FlyBase]
FBpp0292967 [FlyBase]
FBpp0292966 [FlyBase]
Ilp6-PA / FBpp0070390 [FlyBase]
Description(s) found:
Found 43 descriptions.
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  • type=protein; loc=X:complement(2225771..2225880,2225959..2226172); ID=FBpp0305878; name=Ilp6-PD; parent=FBgn0044047,FBtr0333731; dbxref=REFSEQ:NP_001259185,GB_protein:AGB95031,FlyBase:FBpp0305878,FlyBase_Annotation_IDs:CG14049-PD; MD5=3a34b4760b378901a88ac10ffe0546cd; length=107; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:complement(2225771..2225880,2225959..2226172); ID=FBpp0292967; name=Ilp6-PC; parent=FBgn0044047,FBtr0303998; dbxref=FlyBase:FBpp0292967,FlyBase_Annotation_IDs:CG14049-PC,REFSEQ:NP_001188539,GB_protein:ADV37623; MD5=3a34b4760b378901a88ac10ffe0546cd; length=107; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:complement(2225771..2225880,2225959..2226172); ID=FBpp0292966; name=Ilp6-PB; parent=FBgn0044047,FBtr0303997; dbxref=FlyBase:FBpp0292966,FlyBase_Annotation_IDs:CG14049-PB,REFSEQ:NP_001188538,GB_protein:ADV37622; MD5=3a34b4760b378901a88ac10ffe0546cd; length=107; release=r5.56; species=Dmel; [FlyBase]
  • The gene Insulin-like peptide 6 is referred to in FlyBase by the symbol Dmel\Ilp6 (CG14049, FBgn0044047). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2225439..2227719. It has the cytological map location 3A1. Based on sequence similarity, it is predicted to have molecular function</span>: insulin receptor binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: insulin receptor signaling pathway. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 107 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [ISS]
    Biological Process: insulin receptor signaling pathway [ISS]
    positive regulation of multicellular organism growth [IMP]
    Molecular Function: insulin receptor binding [ISS]
    hormone activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLKVPTSKV LLVLATLFAV AAMISSWMPQ VAASPLAPTE YEQRRMMCST GLSDVIQKIC  60
   61 VSGTVALGDV FPNSFGKRRK RDLQNVTDLC CKSGGCTYRE LLQYCKG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] FFAS03 1.33 Insulin-like growth factor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor binding
    		•  4.59183117612989 bayes_pls_golite062009
  • insulin-like growth factor receptor binding
    		•  3.91392491671741 bayes_pls_golite062009
  • growth factor activity
    		•  3.82223614188869 bayes_pls_golite062009
  • insulin receptor binding
    		•  3.29339271267896 bayes_pls_golite062009
  • binding
    		•  1.97432615074248 bayes_pls_golite062009
  • growth factor binding
    		•  1.64794458051288 bayes_pls_golite062009
  • insulin-like growth factor binding
    		•  1.58320511785821 bayes_pls_golite062009
  • protein binding
    		•  1.49599385682338 bayes_pls_golite062009
  • hormone activity
    		•  1.12793487496998 bayes_pls_golite062009
  • protein complex binding
    		•  1.04333094834193 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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