Protein Overview: pn-PA

General Information:
Name(s) found:	pn-PA / FBpp0070373 [FlyBase]
Description(s) found: Found 26 descriptions. SHOW ALL	The gene prune is referred to in FlyBase by the symbol Dmel\pn (CG3461, FBgn0003116). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2075127..2076972. It has the cytological map location 2E1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: manganese ion binding; pyrophosphatase activity. There is experimental evidence that it is involved in the biological process</span>: compound eye pigmentation. 105 alleles are reported. The phenotype of these alleles is annotated with: pigment cell. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	405 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	compound eye pigmentation [IMP]
Molecular Function:	pyrophosphatase activity [IEA] manganese ion binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCFLRFLAQA RGTLGRHLAE ASPVAWAAAP DVSGRKLHLV MGNESCDLDS AVSAVTLAFV  60
   61 YAQRHREHDY VPILNIPRRD YPLKTEVGHL FVKCGIAEPV LLFRDDIPRE VVQDVNVILV 120
  121 DHHVSPLAPN VTEILDHRPL EDSSPSFKQL PTLCQLDIDA SVGSCATLVA QRYLAEDQPR 180
  181 STSVAQLLHA TIVLDTINFA PAAKRYGPKD EAMVQKLESE LNRKDAQRSS LFDELVAARA 240
  241 DISKLTLTEV LRKDMKVLQT DRQVVPLAGM PILVRDFVEK SGAEKAVREF GVESNLLVIL 300
  301 GMYVSPADGQ VQRDLALISL SGQGQFVQRV QQALMESNDP KLELRPHEVD TRFMGGCFLR 360
  361 QHNVQATRKH ILPIVKRALL EWEADHACDC DEVYFFKEKP QLGLS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
nuclease activity	2.22762374984422	bayes_pls_golite062009
hydrolase activity	2.11996205929773	bayes_pls_golite062009
catalytic activity	1.78154379547895	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.7679956422453	bayes_pls_golite062009
deoxyribonuclease activity	1.7238398802096	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1.48438369225803	bayes_pls_golite062009
exonuclease activity	1.4791620684568	bayes_pls_golite062009
binding	1.44809983424821	bayes_pls_golite062009
single-stranded DNA specific exodeoxyribonuclease activity	1.10404503151762	bayes_pls_golite062009
exodeoxyribonuclease activity	0.808006273031307	bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.792120683260194	bayes_pls_golite062009
protein binding	0.409982335293186	bayes_pls_golite062009
inorganic diphosphatase activity	0.158887418739632	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.66

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..405]	PSI-BLAST	55.0	Manganese-dependent inorganic pyrophosphatase (family II)

Protein Overview: pn-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: