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Protein Overview: east-PB, FBpp029...

General Information:
Name(s) found: FBpp0292166 [FlyBase]
FBpp0292165 [FlyBase]
east-PB / FBpp0070312 [FlyBase]
Description(s) found:
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  • gi|24639236|ref|NP_524864.2| enhanced adult sensory threshold [Drosophila melanogaster] [NCBI NR]
  • gi|22831540|gb|AAF45704.2| enhanced adult sensory threshold [Drosophila melanogaster] [NCBI NR]
  • type=protein; loc=X:join(1908555..1912037,1912113..1912119,1912738..1912971,1913091..1913539,1913601..1913770,1913881..1915150,1915205..1916497); ID=FBpp0292166; name=east-PD; parent=FBgn0261954,FBtr0303047; dbxref=FlyBase:FBpp0292166,FlyBase_Annotation_IDs:CG4399-PD,REFSEQ:NP_001188531,GB_protein:ADV37615; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=X:join(1908555..1912037,1912113..1912119,1912738..1912971,1913091..1913539,1913601..1913770,1913881..1915150,1915205..1916497); ID=FBpp0292165; name=east-PC; parent=FBgn0261954,FBtr0303046; dbxref=FlyBase:FBpp0292165,FlyBase_Annotation_IDs:CG4399-PC,REFSEQ:NP_001188530,GB_protein:ADV37614; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r5.56; species=Dmel; [FlyBase]
  • The gene enhanced adult sensory threshold is referred to in FlyBase by the symbol Dmel\east (CG4399, FBgn0010110). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1906357..1916691. It has the cytological map location 2C2-2C4. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: zinc ion binding; metallocarboxypeptidase activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; achiasmate meiosis I; mitotic metaphase. 26 alleles are reported. The phenotypes of these alleles are annotated with: spermatogonium; larval salivary gland. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG4399-PB translation from_gene[CG4399 east FBgn0010110] seq_release:3 mol_weight=245707 cds_boundaries:(X:1,771,294..1,779,233[+]) aa_length:2301 transcript_info:[CG4399-RB seq_release:3] gene_info:[gene symbol:east FBgn0010110 gene_boundaries:(X:1,7 [hmr_yeast5_DM3-1_pombe.fasta]
  • (AAF45704) CG4399-PB [DrosMelano7227.FASTAC.txt]
  • CG4399-PB [Drosophila melanogaster]gi|24639236|ref|NP_524864.2| CG4399-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(1908555..1912037,1912113..1912119,1912738..1912971,1913091..1913539,1913601..1913770,1913881..1915150,1915205..1916497); ID=FBpp0070312; name=east-PB; parent=FBgn0010110,FBtr0070326; dbxref=FlyBase:FBpp0070312,FlyBase_Annotation_I [fly-100309-contam.fasta]
  • CG4399-PB [Drosophila melanogaster] [nr-271106-contam.fasta]
  • enhanced adult sensory threshold CG4399-PB [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(1908555..1912037,1912113..1912119,1912738..1912971,1913091..1913539,1913601..1913770,1913881..1915150,1915205..1916497); ID=FBpp0070312; name=east-PB; parent=FBgn0010110,FBtr0070326; dbxref=FlyBase:FBpp0070312,FlyBase_Annotation_IDs:CG4399-PB,GB_protein:AAF45704.2,REFSEQ:NP_524864,GB_protein:AAF45704; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(1908555..1912037,1912113..1912119,1912738..1912971,1913091..1913539,1913601..1913770,1913881..1915150,1915205..1916497); ID=FBpp0070312; name=east-PB; parent=FBgn0010110,FBtr0070326; dbxref=FlyBase:FBpp0070312,FlyBase_Annotation_IDs:CG4399-PB,GB_protein:AAF45704.2,REFSEQ:NP_524864,GB_protein:AAF45704; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Enhanced adult sensory threshold OS=Drosophila melanogaster GN=east PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:join(1908555..1912037,1912113..1912119,1912738..1912971,1913091..1913539,1913601..1913770,1913881..1915150,1915205..1916497); ID=FBpp0292165; name=east-PC; parent=FBgn0261954,FBtr0303046; dbxref=FlyBase:FBpp0292165,FlyBase_Annotation_IDs:CG4399-PC,REFSEQ:NP_001188530,GB_protein:ADV37614; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(1908555..1912037,1912113..1912119,1912738..1912971,1913091..1913539,1913601..1913770,1913881..1915150,1915205..1916497); ID=FBpp0070312; name=east-PB; parent=FBgn0261954,FBtr0070326; dbxref=FlyBase:FBpp0070312,FlyBase_Annotation_IDs:CG4399-PB,GB_protein:AAF45704.2,REFSEQ:NP_524864,GB_protein:AAF45704,FlyMine:FBpp0070312,modMine:FBpp0070312; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(1908555..1912037,1912113..1912119,1912738..1912971,1913091..1913539,1913601..1913770,1913881..1915150,1915205..1916497); ID=FBpp0292166; name=east-PD; parent=FBgn0261954,FBtr0303047; dbxref=FlyBase:FBpp0292166,FlyBase_Annotation_IDs:CG4399-PD,REFSEQ:NP_001188531,GB_protein:ADV37615; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0292165; name=east-PC; parent=FBgn0261954,FBtr0303046; dbxref=FlyBase:FBpp0292165,FlyBase_Annotation_IDs:CG4399-PC,REFSEQ:NP_001188530,GB_protein:ADV37614; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0070312; name=east-PB; parent=FBgn0261954,FBtr0070326; dbxref=FlyBase:FBpp0070312,FlyBase_Annotation_IDs:CG4399-PB,GB_protein:AAF45704.2,REFSEQ:NP_524864,GB_protein:AAF45704,FlyMine:FBpp0070312,modMine:FBpp0070312; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0292166; name=east-PD; parent=FBgn0261954,FBtr0303047; dbxref=FlyBase:FBpp0292166,FlyBase_Annotation_IDs:CG4399-PD,REFSEQ:NP_001188531,GB_protein:ADV37615; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0292165; name=east-PC; parent=FBgn0261954,FBtr0303046; dbxref=FlyBase:FBpp0292165,FlyBase_Annotation_IDs:CG4399-PC,REFSEQ:NP_001188530,GB_protein:ADV37614; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0070312; name=east-PB; parent=FBgn0261954,FBtr0070326; dbxref=FlyBase:FBpp0070312,FlyBase_Annotation_IDs:CG4399-PB,GB_protein:AAF45704.2,REFSEQ:NP_524864,GB_protein:AAF45704,FlyMine:FBpp0070312,modMine:FBpp0070312; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0292166; name=east-PD; parent=FBgn0261954,FBtr0303047; dbxref=FlyBase:FBpp0292166,FlyBase_Annotation_IDs:CG4399-PD,REFSEQ:NP_001188531,GB_protein:ADV37615; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of O46048, Enhanced adult sensory threshold, isoform B OS=Drosophila melanogaster GN=east PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0292165 type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0292165; name=east-PC; parent=FBgn0261954,FBtr0303046; dbxref=FlyBase:FBpp0292165,FlyBase_Annotation_IDs:CG4399-PC,REFSEQ:NP_001188530,GB_protein:ADV37614; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0070312 type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0070312; name=east-PB; parent=FBgn0261954,FBtr0070326; dbxref=FlyBase:FBpp0070312,FlyBase_Annotation_IDs:CG4399-PB,GB_protein:AAF45704.2,REFSEQ:NP_524864,GB_protein:AAF45704,FlyMine:FBpp0070312,modMine:FBpp0070312; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0292166 type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0292166; name=east-PD; parent=FBgn0261954,FBtr0303047; dbxref=FlyBase:FBpp0292166,FlyBase_Annotation_IDs:CG4399-PD,REFSEQ:NP_001188531,GB_protein:ADV37615; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0292165; name=east-PC; parent=FBgn0261954,FBtr0303046; dbxref=FlyBase:FBpp0292165,FlyBase_Annotation_IDs:CG4399-PC,REFSEQ:NP_001188530,GB_protein:ADV37614,UniProt/TrEMBL:Q7KW02; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0070312; name=east-PB; parent=FBgn0261954,FBtr0070326; dbxref=FlyBase:FBpp0070312,FlyBase_Annotation_IDs:CG4399-PB,GB_protein:AAF45704.2,REFSEQ:NP_524864,GB_protein:AAF45704,UniProt/TrEMBL:Q7KW02,FlyMine:FBpp0070312,modMine:FBpp0070312; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=X:join(2014522..2018004,2018080..2018086,2018705..2018938,2019058..2019506,2019568..2019737,2019848..2021117,2021172..2022464); ID=FBpp0292166; name=east-PD; parent=FBgn0261954,FBtr0303047; dbxref=FlyBase:FBpp0292166,FlyBase_Annotation_IDs:CG4399-PD,REFSEQ:NP_001188531,GB_protein:ADV37615,UniProt/TrEMBL:Q7KW02; MD5=8ad14f275d9a966b38105fead97e15c9; length=2301; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 2301 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    [NOT]nuclear chromosome [IDA]
    [NOT]nucleolus [IDA]
    Biological Process: mitotic metaphase [IMP]
    achiasmate meiosis I [IMP]
    proteolysis [IEA]
    female meiosis chromosome segregation [IMP]
    Molecular Function: zinc ion binding [IEA]
    metallocarboxypeptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRKVPGGS GGADESTAAA APLDDNANAS VEIPDSSEEP AMGVGEEMSI ISKTRTSTLS  60
   61 VEPAKEPTVT AELEGEKELE SNPVSKTPRS TPTPTLTPAV TPTASDGVAA KSVRVTRHSS 120
  121 PLLLIISPTT SRREVGDGEL DTEEPTGSGG QRKSSVERSL APVIRGRKSI KDLKEAKEVK 180
  181 SEEPPAAASE SRAASGVTPG QVKEQHVADG NEMESLPITD KKDHKDTKDK GDERETDQEE 240
  241 EKEKSADTEI IADTEKTSEK QKYTEKDKAA DKDGGKEKDI DANKDIDKEK EKVKEVLPPV 300
  301 VPIAPVTPTC NRVTRKSHAQ EQAINTRVTR NRRQSSTVGA NSTASLVAAS SSVTEQPPPS 360
  361 RGRRKKPVVV APPLEPAVKR KRSQDVEADS DANNSTKYSK VEVVKSEEAE APEEDSSAVP 420
  421 IKQESVDGNE VSSISPTVTP TPTPAPTPAP VPGSRRGRGR PQNRNSSSPA TTTRATRLSK 480
  481 AGSPVILTPV AQEPAPPKRR RVGSSTRKTV SASSLAPSSQ GGAGDEDSKD SMASSMDDLL 540
  541 MAAADIKQEK LTPDFDDSLM PEGLPSTSGA SSANGHSCTE PLTVDTEINV KPADSKVKPK 600
  601 ESPVVAVEES PSQSETQSAK VSAHAGKAPS LSPDMISEGV SAVSVRKFYK KPEFLENNLG 660
  661 IEKDPELGEI VQTVSNNDTE TDVEMAVDGE VNQPSTPKSQ DKKKEEQEKN QKSGLKAAKK 720
  721 APAKLEPKAE DISEILTDVP VDISTEAVEI IEEAEEDTCS NSSIKPGELR LDESNDEPEL 780
  781 LLEDALIVNG DENETPDQPE EKEDQVEFFH TGEYDDFEHE IMVELAKEGV LDASGNALSQ 840
  841 QKVELEHPED VTLHESKNDI EAEESVERKP LKDPSVADEM EDMNEESYID IKDQTNQLLV 900
  901 EHLAEEAMEA DCGPEDNKEN LSTSASSTAA DGLDIQLAIK EDDDEEKPLA VIADEQKPGL 960
  961 LLTNDMKVDE KPNGKQESVC DEHVQLVPNL RQEQEIHLQN LGLLTHQAAE HRRKCLLEAQ1020
 1021 ARQAQMQLQQ HHHHQHKRQG ARGGGSATHV ESSGTLKTVI KLNRSSNGGV SGSGGLPTGT1080
 1081 VIHGGCGSSS ASSTSSSSVG SATRKSSGTL GSGAGAGAGV RRQSLKMTFQ KGRARGHGAA1140
 1141 DRSADQYGAH AEDSYYTIQN ENEDSSHSES QGQTDHGFYQ MVKKDEKEKI LIPEKASSFK1200
 1201 FHPGRLCEDQ CYYCSGKFGL YDTPCHVGQI KSVERQQKIL ANEEKLTVDN CLCDACFRHV1260
 1261 DRRANVPSYK KRLSASGHLE MGSAAGSALE KQFAGDSGVI TESGGEAGST AAVAVQQRSC1320
 1321 GVKDCVEAAR HSLRRKCIRK RVKKYQLSLE IPAGSSNVGL CEAHYNTVIQ FSGCVLCKRR1380
 1381 LGKNHMYNIT TQDTIRLEKA LSEMGIPVQL GMGTAVCKLC RYFANLLIKP PDSTKAQKAE1440
 1441 FVKNYRKRLL KVHNLQDGSH ELSEADEEEA PNATETERPT SDGHEDPEMP MVADYDGPTD1500
 1501 SNSSSSSTAA LDTSKQMSKL QAILQQNVGA DAAGAAGTGT VAASPGGSGS GADISNVLRG1560
 1561 NPNISMRELF HGEEELGVQF KVPFGCSSSQ RTPEGWTRVQ TFLQYDEPTR RLWEELQKPY1620
 1621 GNQSSFLRHL ILLEKYYRNG DLVLAPHASS NATVYTETVR QRLNSFDHGH CGGLNIAGSP1680
 1681 SSSGSGKRSG VPQPTGASVL ATALTTPLTS HSSSSASISS EQHSSVDPVI PLVDLNDDDE1740
 1741 GEDGAGGAGE RESTNRQQDV ILECLRTASV DKLTKQLSSN AVTIIARPKD KSQLSCNSGS1800
 1801 STSISSSSSA ISSPEEVAVT KVTAVAPVQS KDAPPLAPAS SGVSNSRSIL KTNLLGMNKA1860
 1861 VELVPLTTAP HAYKPTGCHK PEKQQKILDV ANKQPGSQGE PVPSSALLGL QSKLKPPTHQ1920
 1921 QQVSGSGAGT SGSQKPSNVA QLLSSPPELI SLHRRQTSGA AAGSSSFLQG KRLQLPRSGA1980
 1981 GPSGAGTGTG AGAAGSRSAG GPPPPNVVIL PDALTPQERH ESKSWKPTLI PLEDQHKVPN2040
 2041 KSHALYQTAD GRRLPALVQV QSGGKPYLIS IFDYNRMCIL RREKLMRDQL LKSNAKPKPQ2100
 2101 NQQQQQGQTH QQQQNSAASA AAFSNMVKLA QQHTARQQLQ QLQQKPQQQQ QLPTLQPGGV2160
 2161 RLARLPQKLL MPPLTNPQIG SQAPNLQPLL SSTLDNSNNC WLWKNFPDPN QYLLNGNGGG2220
 2221 AGSSSSKLPH LTAKPATATS SSGAANKSAG SLFTLKQQQH QQKLIDNAIM SKIPKSLTVI2280
 2281 PQQMGGNTGG DMGGSSSSGK D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..190] MSA 2.335997 View MSA. No confident structure predictions are available.
    2 View Details [191..467] deduced N/A No confident structure predictions are available.
    3 View Details [468..686] deduced N/A No confident structure predictions are available.
    4 View Details [687..852] deduced N/A No confident structure predictions are available.
    5 View Details [853..1030] deduced N/A No confident structure predictions are available.
    6 View Details [1031..1159] FFAS03 0.982 Thermus thermophilus Leucyl-tRNA synthetase complexed with with a tRNAleu transcript in the post-editing conformation and a post- transfer editing subsrate analogue
    7 View Details [1160..1304] MSA 2.292996 View MSA. No confident structure predictions are available.
    8 View Details [1305..1498] deduced N/A No confident structure predictions are available.
    9 View Details [1499..1673] deduced N/A No confident structure predictions are available.
    10 View Details [1674..1817] deduced N/A No confident structure predictions are available.
    11 View Details [1818..1986] deduced N/A No confident structure predictions are available.
    12 View Details [1987..2053] deduced N/A No confident structure predictions are available.
    13 View Details [2054..2122] deduced N/A No confident structure predictions are available.
    14 View Details [2123..2183] deduced N/A No confident structure predictions are available.
    15 View Details [2184..2301] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle