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Protein Overview: l(1)1Bi-PA

General Information:
Name(s) found: l(1)1Bi-PA / FBpp0070114 [FlyBase]
Description(s) found:
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  • gi|7290066|gb|AAF45532.1| lethal (1) 1Bi [Drosophila melanogaster] [NCBI NR]
  • gi|24638923|ref|NP_476593.2| lethal (1) 1Bi [Drosophila melanogaster] [NCBI NR]
  • The gene lethal (1) 1Bi is referred to in FlyBase by the symbol Dmel\l(1)1Bi (CG6189, FBgn0001341). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:523816..527666. It has the cytological map location 1B12. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: DNA binding; DNA-directed DNA polymerase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transcription. 17 alleles are reported. The phenotype of these alleles is annotated with: macrochaeta. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG6189-PA translation from_gene[CG6189 l(1)1Bi FBgn0001341] seq_release:3 mol_weight=127868 cds_boundaries:(X:387,323..390,902[+]) aa_length:1133 transcript_info:[CG6189-RA seq_release:3] gene_info:[gene symbol:l(1)1Bi FBgn0001341 gene_boundaries:(X:3 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W5E4) L(1)1BI protein [DrosMelano7227.FASTAC.txt]
  • (AE003418) l(1)1Bi gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG6189-PA [Drosophila melanogaster]gi|24638923|ref|NP_476593.2| CG6189-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(523919..524242,524306..524677,524736..526016,526077..527501); ID=FBpp0070114; name=l(1)1Bi-PA; parent=FBgn0001341,FBtr0070119; dbxref=FlyBase:FBpp0070114,FlyBase_Annotation_IDs:CG6189-PA,GB_protein:AAF45532.1,REFSEQ:NP_476593,GB_p [fly-100309-contam.fasta]
  • CG6189-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • lethal (1) 1Bi CG6189-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(523919..524242,524306..524677,524736..526016,526077..527501); ID=FBpp0070114; name=l(1)1Bi-PA; parent=FBgn0001341,FBtr0070119; dbxref=FlyBase:FBpp0070114,FlyBase_Annotation_IDs:CG6189-PA,GB_protein:AAF45532.1,REFSEQ:NP_476593,GB_protein:AAF45532; MD5=20bd304c92909bab340dac5751adc798; length=1133; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(523919..524242,524306..524677,524736..526016,526077..527501); ID=FBpp0070114; name=l(1)1Bi-PA; parent=FBgn0001341,FBtr0070119; dbxref=FlyBase:FBpp0070114,FlyBase_Annotation_IDs:CG6189-PA,GB_protein:AAF45532.1,REFSEQ:NP_476593,GB_protein:AAF45532; MD5=20bd304c92909bab340dac5751adc798; length=1133; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Lethal (1) 1Bi OS=Drosophila melanogaster GN=l(1)1Bi PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:join(523919..524242,524306..524677,524736..526016,526077..527501); ID=FBpp0070114; name=l(1)1Bi-PA; parent=FBgn0001341,FBtr0070119; dbxref=FlyBase:FBpp0070114,FlyBase_Annotation_IDs:CG6189-PA,GB_protein:AAF45532.1,REFSEQ:NP_476593,GB_protein:AAF45532,FlyMine:FBpp0070114,modMine:FBpp0070114; MD5=20bd304c92909bab340dac5751adc798; length=1133; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(629886..630209,630273..630644,630703..631983,632044..633468); ID=FBpp0070114; name=l(1)1Bi-PA; parent=FBgn0001341,FBtr0070119; dbxref=FlyBase:FBpp0070114,FlyBase_Annotation_IDs:CG6189-PA,GB_protein:AAF45532.1,REFSEQ:NP_476593,GB_protein:AAF45532,FlyMine:FBpp0070114,modMine:FBpp0070114; MD5=20bd304c92909bab340dac5751adc798; length=1133; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(629886..630209,630273..630644,630703..631983,632044..633468); ID=FBpp0070114; name=l(1)1Bi-PA; parent=FBgn0001341,FBtr0070119; dbxref=FlyBase:FBpp0070114,FlyBase_Annotation_IDs:CG6189-PA,GB_protein:AAF45532.1,REFSEQ:NP_476593,GB_protein:AAF45532,FlyMine:FBpp0070114,modMine:FBpp0070114; MD5=20bd304c92909bab340dac5751adc798; length=1133; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FI21448p1 OS=Drosophila melanogaster GN=l(1)1Bi PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0070114 type=protein; loc=X:join(629886..630209,630273..630644,630703..631983,632044..633468); ID=FBpp0070114; name=l(1)1Bi-PA; parent=FBgn0001341,FBtr0070119; dbxref=FlyBase:FBpp0070114,FlyBase_Annotation_IDs:CG6189-PA,GB_protein:AAF45532.1,REFSEQ:NP_476593,GB_protein:AAF45532,FlyMine:FBpp0070114,modMine:FBpp0070114; MD5=20bd304c92909bab340dac5751adc798; length=1133; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:join(629886..630209,630273..630644,630703..631983,632044..633468); ID=FBpp0070114; name=l(1)1Bi-PA; parent=FBgn0001341,FBtr0070119; dbxref=FlyBase:FBpp0070114,FlyBase_Annotation_IDs:CG6189-PA,GB_protein:AAF45532.1,REFSEQ:NP_476593,GB_protein:AAF45532,UniProt/TrEMBL:Q9W5E4,FlyMine:FBpp0070114,modMine:FBpp0070114; MD5=20bd304c92909bab340dac5751adc798; length=1133; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1133 amino acids

    Gene Ontology:
    Cellular Component: nucleolus [NAS]
    Biological Process: transcription [IEA]
    Molecular Function: DNA binding [IEA]
    DNA-directed DNA polymerase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSKVDKPVT NGAPNATKTK AKEDRKRAKT QKSEADSQIP AKILKKSKKE KPAETEEKEN  60
   61 TASNANLKVS QINKAVFVVF KKMQGSQLTK KMINSLITLL RDDTNAEQRT ATTGYVLKRL 120
  121 IRSTGADDMK TVSLAASYIH CILNAVPAID AFEVLETLKR DLAVGSQQRG KEDSLAAVGQ 180
  181 LVTAFCILQT PQFAKAEPKL VTAVFQILAA QLKGREYLVS LCGDILAVSF KQLPAAIFEE 240
  241 YVWPLLQPEL NKPLSGLKVN TCDVLLAVHL TFSSVLGREN ILASLWPKKP VYTQLFDLYF 300
  301 SGSTIHSDGV YARLASFLVN GGKDMLAAWQ QYIDSKQPLK LNAAKACAIQ VLSHVLLNFK 360
  361 PREEQLILDI FTPTCVQFLL HECSSVKWDK GEGKKPSLKK LKEICFKFEG SLVLCYEKQF 420
  421 QNDDNKLHLL LKLLEHTLQL DSVISLPRFC QKLINQLSVE SLHKLYDYYN NKLYSLEDED 480
  481 RVSRVHCLNQ MQLILNHSKL SQTAKWRQKQ LNYLLLAGLF HLDASKKPCE AAQASAFSRQ 540
  541 CAARCEEIFL GSLLHKCSGL PGLCQLLQKT LSYLNKELGQ PDAESKLRSP RDESLQKAWK 600
  601 QVEKLLERPS KESDVVGQSF EALILFVSLA LCTKIPPSIT VLEDLIICRK NALQKSKEQV 660
  661 NEELKWQDVL TDALLQLLLQ TGHFWREFVQ LVATALIPHL EHGNLEQVLE VLNMNKNPLS 720
  721 KKSDGEEESD DELDKEESLK DSSDDSEDED EDEEEDEGED DAESHLAQIR ESVRQALVND 780
  781 GDADDDGASS VDWNDVDEEQ GERLNAALER SFQMFRPKSR KAQEKERPTK SERIDSTNLL 840
  841 HFRIRALDLL ELFITKKPTQ SVILDVLHCV FQVYSHCAAD SKLQSLREAS LKLLKKILAR 900
  901 NIELKENQST APILEAIEQL MSSGEEHSEE DQENGKQPAS RQAKRDIIIW RDRCFAYLVS 960
  961 QASADGEPKK SAVWPLLVEF LELWVAKRRS RLSLASFEAL FQSGQWQGVA PLAVVLASHL1020
 1021 DVQKTRSFRR AQILKLLSEQ GRRLEVAFKD NNSSSKKFEK QIARYVNQLE TKASSSKELN1080
 1081 LLLKILAQGG EKWQKLREQI QLVAKDLQPN KKVAKQKKQA AAKPMVVEDE EST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..898] FFAS03 1.03 CBP80, 80KDa nuclear cap-binding protein
    2 View Details [899..1133] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle