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Protein Overview: gw-PF, gw-PA, gw...

General Information:
Name(s) found: gw-PF / FBpp0088170 [FlyBase]
gw-PA / FBpp0088169 [FlyBase]
gw-PE / FBpp0088166 [FlyBase]
gw-PB / FBpp0088165 [FlyBase]
Description(s) found:
Found 90 descriptions.
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  • The gene gawky is referred to in FlyBase by the symbol Dmel\gw (CG31992, FBgn0051992). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:670575..682391. It has the cytological map location 102D2-102D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleotide binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: mRNA catabolic process; embryonic development via the syncytial blastoderm; gene silencing by miRNA. 12 alleles are reported. No phenotypic data is available. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
  • The gene gawky is referred to in FlyBase by the symbol Dmel\gw (CG31992, FBgn0051992). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:670575..682391. It has the cytological map location 102D2-102D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleotide binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: mRNA catabolic process; embryonic development via the syncytial blastoderm; gene silencing by miRNA. 12 alleles are reported. No phenotypic data is available. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
  • The gene gawky is referred to in FlyBase by the symbol Dmel\gw (CG31992, FBgn0051992). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:670575..682391. It has the cytological map location 102D2-102D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleotide binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: mRNA catabolic process; embryonic development via the syncytial blastoderm; gene silencing by miRNA. 12 alleles are reported. No phenotypic data is available. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
  • The gene gawky is referred to in FlyBase by the symbol Dmel\gw (CG31992, FBgn0051992). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:670575..682391. It has the cytological map location 102D2-102D3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: nucleotide binding; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: mRNA catabolic process; embryonic development via the syncytial blastoderm; gene silencing by miRNA. 12 alleles are reported. No phenotypic data is available. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1384 amino acids

    Gene Ontology:
    Cellular Component: cytoplasmic mRNA processing body [IDA]
    Biological Process: [NOT]nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IMP]
    embryonic development via the syncytial blastoderm [IDA]
    gene silencing by miRNA [IMP]
    mRNA catabolic process [IMP]
    Molecular Function: nucleotide binding [IEA]
    nucleic acid binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREALFSQDG WGCQHVNQDT NWEVPSSPEP ANKDAPGPPM WKPSINNGTD LWESNLRNGG  60
   61 QPAAQQVPKP SWGHTPSSNL GGTWGEDDDG ADSSSVWTGG AVSNAGSGAA VGVNQAGVNV 120
  121 GPGGVVSSGG PQWGQGVVGV GLGSTGGNGS SNITGSSGVA TGSSGNSSNA GNGWGDPREI 180
  181 RPLGVGGSMD IRNVEHRGGN GSGATSSDPR DIRMIDPRDP IRGDPRGISG RLNGTSEMWG 240
  241 HHPQMSHNQL QGINKMVGQS VATASTSVGT SGSGIGPGGP GPSTVSGNIP TQWGPAQPVS 300
  301 VGVSGPKDMS KQISGWEEPS PPPQRRSIPN YDDGTSLWGQ QTRVPAASGH WKDMTDSIGR 360
  361 SSHLMRGQSQ TGGIGIAGVG NSNVPVGANP SNPISSVVGP QARIPSVGGV QHKPDGGAMW 420
  421 VHSGNVGGRN NVAAVTTWGD DTHSVNVGAP SSGSVSSNNW VDDKSNSTLA QNSWSDPAPV 480
  481 GVSWGNKQSK PPSNSASSGW STAAGVVDGV DLGSEWNTHG GIIGKSQQQQ KLAGLNVGMV 540
  541 NVINAEIIKQ SKQYRILVEN GFKKEDVERA LVIANMNIEE AADMLRANSS LSMDGWRRHD 600
  601 ESLGSYADHN SSTSSGGFAG RYPVNSGQPS MSFPHNNLMN NMGGTAVTGG NNNTNMTALQ 660
  661 VQKYLNQGQH GVAVGPQAVG NSSAVSVGFG QNTSNAAVAG AASVNIAANT NNQPSGQQIR 720
  721 MLGQQIQLAI HSGFISSQIL TQPLTQTTLN LLNQLLSNIK HLQAAQQSLT RGGNVNPMAV 780
  781 NVAISKYKQQ IQNLQNQINA QQAVYVKQQN MQPTSQQQQP QQQQLPSVHL SNSGNDYLRG 840
  841 HDAINNLQSN FSELNINKPS GYQGASNQQS RLNQWKLPVL DKEINSDSTE FSRAPGATKQ 900
  901 NLTANTSNIN SLGLQNDSTW STGRSIGDGW PDPSSDNENK DWSVAQPTSA ATAYTDLVQE 960
  961 FEPGKPWKGS QIKSIEDDPS ITPGSVARSP LSINSTPKDA DIFANTGKNS PTDLPPLSLS1020
 1021 SSTWSFNPNQ NYPSHSWSDN SQQCTATSEL WTSPLNKSSS RGPPPGLTAN SNKSANSNAS1080
 1081 TPTTITGGAN GWLQPRSGGV QTTNTNWTGG NTTWGSSWLL LKNLTAQIDG PTLRTLCMQH1140
 1141 GPLVSFHPYL NQGIALCKYT TREEANKAQM ALNNCVLANT TIFAESPSEN EVQSIMQHLP1200
 1201 QTPSSTSSSG TSGGNVGGVG TSANNANSGS AACLSGNNSG NGNGSASGAG SGNNGNSSCN1260
 1261 NSAAGGGSSS NNTITTVANS NLVGSSGSVS NSSGVTANSS TVSVVSCTAS GNSINGAGTA1320
 1321 NSSGSKSSAN NLASGQSSAS NLTNSTNSTW RQTSQNQALQ SQSRPSGREA DFDYISLVYS1380
 1381 IVDD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1006] PSI-BLAST 89.0 No description for 1y0fA was found.
    2 View Details [1007..1116] PSI-BLAST 3.69897 Fibrinogen
    3 View Details [1117..1384] MSA 3.028996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle