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Protein Overview: FBpp0305832, CG1...

General Information:
Name(s) found: FBpp0305832 [FlyBase]
CG1970-PA / FBpp0088174 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • type=protein; loc=4:complement(588993..589682,589740..589927,590601..590802,590860..590969,591035..591159,591230..591321); ID=FBpp0305832; name=CG1970-PB; parent=FBgn0039909,FBtr0333676; dbxref=REFSEQ:NP_001259064,GB_protein:AGB96554,FlyBase:FBpp0305832,FlyBase_Annotation_IDs:CG1970-PB; MD5=34fc4f346cb05e74e8ae5dbf4d537486; length=468; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG1970 (CG1970, FBgn0039909). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:588914..591420. It has the cytological map location 102C5. Based on sequence similarity, it is predicted to have molecular function</span>: NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, NADH to ubiquinone. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 468 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex I [ISS]
    Biological Process: mitochondrial electron transport, NADH to ubiquinone [ISS]
    Molecular Function: NADH dehydrogenase activity [ISS]
    quinone binding [IEA]
    NAD or NADH binding [IEA]
    NADH dehydrogenase (ubiquinone) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANIMRRTLI PGLSHLRLRP QLVAAGSAAL TSQETRRGAA KWYPDPEFMK QFSGPVMYPD  60
   61 EVTSLWTVPP WNSKVTPVEK SVRNLTLNFG PQHPAAHGVL RLVLELDGET VMRADPHIGL 120
  121 LHRGTEKLIE YKTYTQALPY FDRLDYVSMM CNEQCYSLAV EKLLNIDVPL RAKYIRTLFA 180
  181 EITRILNHIM AVGTHALDVG ALTPFFWLFE EREKMMEFYE RVSGARMHAA YIRPGGVSLD 240
  241 MPLGLMDDIY EFASKFAERL DEVEDVLTTN RIWVQRTEDI GIVTAEEALN YGFSGVMLRG 300
  301 SGIKWDLRKQ QPYDAYNLVN FDVPIGTKGD CYDRYLCRVE EMRQSLRIID QCLNQMPAGE 360
  361 IKTDDAKVAP PSRSEMKTSM EALIHHFKLF TQGYQVPPGA TYTAIEAPKG EFGVYLISDG 420
  421 SSRPYRCKIK APGFAHLAAL EKIGKQHMLA DVVAIIGTLD VVFGEIDR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] PSI-BLAST 6.522879 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
    2 View Details [75..468] PSI-BLAST 122.0 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  13.5914597754866 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  12.311192040385 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  12.1563727867842 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  11.7527486559512 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  11.1653559876285 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.49653654839585 bayes_pls_golite062009
  • ferredoxin hydrogenase activity
    		•  3.63852106070173 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
    		•  3.63852106070173 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor
    		•  3.45611813853803 bayes_pls_golite062009
  • oxidoreduction-driven active transmembrane transporter activity
    		•  2.72460560332491 bayes_pls_golite062009
  • oxidoreductase activity, acting on iron-sulfur proteins as donors
    		•  2.45015987642707 bayes_pls_golite062009
  • catalytic activity
    		•  1.13542026154948 bayes_pls_golite062009
  • binding
    		•  0.855276486319983 bayes_pls_golite062009
  • electron carrier activity
    		•  0.539561648236344 bayes_pls_golite062009
  • protein binding
    		•  0.33547765747527 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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