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Protein Overview: Rad23-PB

General Information:
Name(s) found: Rad23-PB / FBpp0088190 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Rad23 is referred to in FlyBase by the symbol Dmel\Rad23 (CG1836, FBgn0026777). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:328723..330934. It has the cytological map location 102B3. Based on sequence similarity, it is predicted to have molecular function</span>: damaged DNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nucleotide-excision repair. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 343 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: proteasomal ubiquitin-dependent protein catabolic process [IEA]
    nucleotide-excision repair [ISS][NAS]
    Molecular Function: damaged DNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTRDSSSSN RNQLSVKESN KLTSTDDSKQ SMPCEEANHT NSPSSTNTED SVLSRETRPL  60
   61 SSDELIGELA QASLQSRAES NLLMGDEYNQ TVLSMVEMGY PREQVERAMA ASYNNPERAV 120
  121 EYLINGIPAE EGTFYNRLNE STNPSLIPSG PQPASATSAE RSTESNSDPF EFLRSQPQFL 180
  181 QMRSLIYQNP HLLHAVLQQI GQTNPALLQL ISENQDAFLN MLNQPIDRES ESGATVPPVS 240
  241 NARIPSTLDN VDLFSPDLEV ATSAQRSAAG TSAAHQSGSA ADNEDLEQPL GVSTIRLNRQ 300
  301 DKDAIERLKA LGFPEALVLQ AYFACEKNEE QAANFLLSSS FDD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..343] PSI-BLAST 38.221849 Structure of the DNA repair protein hHR23a

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • damaged DNA binding
    		•  2.05780812338496 bayes_pls_golite062009
  • catalytic activity
    		•  0.628189184116182 bayes_pls_golite062009
  • binding
    		•  0.540219151625333 bayes_pls_golite062009
  • DNA binding
    		•  0.41234593519802 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.40496510677618 bayes_pls_golite062009
  • protein binding
    		•  0.186032130230449 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle