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Protein Overview: sip3-PA, FBpp0303146

General Information:
Name(s) found: FBpp0303146 [FlyBase]
sip3-PA / FBpp0085201 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=3R:join(27598276..27598401,27598464..27598520,27598576..27598764,27598819..27599668,27599727..27599941,27599998..27600441); ID=FBpp0303146; name=sip3-PB; parent=FBgn0039875,FBtr0330113; dbxref=FlyBase:FBpp0303146,FlyBase_Annotation_IDs:CG1937-PB,REFSEQ:NP_001263152,GB_protein:AGB96530; MD5=8875102bc219153eea97751f12ae20b5; length=626; release=r5.56; species=Dmel; [FlyBase]
  • The gene septin interacting protein 3 is referred to in FlyBase by the symbol Dmel\sip3 (CG1937, FBgn0039875). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27597938..27600505. It has the cytological map location 100D2. There is experimental evidence that it has the molecular function</span>: protein binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: ER-associated protein catabolic process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 626 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [ISS]
    Biological Process: ER-associated protein catabolic process [ISS]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IPI]
    acid-amino acid ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLLLSSVCM ALTSAVIGFA YYQKQQFYPA VVYITKSNAS MGVIYIQFFV IVFMFGKLLS  60
   61 KIFLGTLRAA EFEHLLERFW YALTETCLAF TVFRDDFNPR FVALFTVLLF LKSFHWLAEE 120
  121 RVDFMERSPV LGWLFHIRVG SLLTVLGILD YVLLIHAYNS TLVRGPTVQL VFGFEYAILL 180
  181 TVIASTAIKY VLHAAEMRTD TPWENKAVFL LYTELVIGLI KVVLYILFVV IMAKIYALPM 240
  241 FVFRPMFFTI RNFRKALNDV IMSRRAIRNM NTLYPDATPE ELRQSDNICI ICREDMVNHS 300
  301 KKLPCGHIFH TTCLRSWFQR QQTCPTCRLN ILRTPTVNST AMPRQGDEAV AAAAGNPIPA 360
  361 AAGVQPAGGV PPPAPTAVVD GNQARADVNV AGGQALPPNF ADLFGDASGL PNGLPNLAGL 420
  421 QIPPPPVMPM ISPFMIPPHF GYLTPLPPPP IPQDLTNFTD EELRAMEGLQ RDHIVQRLKL 480
  481 LQNINLMLDS AGIMMSQYQS LSARLQLTAV TPATAVNGSA DSSVYDMPST SATAMAQLET 540
  541 HQVTPTAAAS SASPTMPAEK VTIEDLGADA DEDDIPSTAT EAVSIPNSDA DFEENSSELG 600
  601 ELRKRRLKFL EERNKSAATN ERTTAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..212] MSA 1.108967 View MSA. No confident structure predictions are available.
    2 View Details [213..260] deduced N/A No confident structure predictions are available.
    3 View Details [261..341] PSI-BLAST 5.0 Cbl; N-terminal domain of cbl (N-cbl); CBL
    4 View Details [342..626] PSI-BLAST 6.0 No description for 1y0fA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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