Protein Overview: nero-PA

General Information:
Name(s) found:	nero-PA / FBpp0085222 [FlyBase]
Description(s) found: Found 23 descriptions. SHOW ALL	The gene nero is referred to in FlyBase by the symbol Dmel\nero (CG2245, FBgn0261479). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27572167..27573251. It has the cytological map location 100D2. Based on sequence similarity, it is predicted to have molecular function</span>: deoxyhypusine monooxygenase activity. There is experimental evidence that it is involved in the biological process</span>: sensory organ development; cell growth; regulation of autophagy; dorsal/ventral lineage restriction, imaginal disc. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	302 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	dorsal/ventral lineage restriction, imaginal disc [IMP] regulation of autophagy [IDA] sensory organ development [IMP] peptidyl-lysine modification to hypusine [ISS] cell growth [IDA]
Molecular Function:	deoxyhypusine monooxygenase activity [ISS] binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSQQQIEAI GGVLNNKERP LKERFRALFT LKNIGGGAAI EAISKAFDDD SALLKHELAY  60
   61 CLGQMQDAQA LDILTKVLKD TTQEPMVRHE AAEAMGAIGH PDVLPILEEY KQDPVVEVAE 120
  121 TCAIALDRVR WLQSGQKVDD SNPYASVDPS PPTAGDKSVT ELKAIYLDAQ QSLFDRYRAM 180
  181 FSLRNLRTEE SVLAIAEGLK DSSALFRHEV AFVLGQLQEP CSIPFLQENL EDRLENEMVR 240
  241 HECAEALGAI ATEDCIQILN RYAEDDKRVV KESCVIALDM CEYENSPEFQ YADGLAKLDA 300
  301 TK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
binding	2.86831493830281	bayes_pls_golite062009
protein transporter activity	1.76509464455143	bayes_pls_golite062009
protein binding	1.63705839411934	bayes_pls_golite062009
nucleic acid binding	1.13208464017585	bayes_pls_golite062009
substrate-specific transporter activity	0.500493982824973	bayes_pls_golite062009
cytoskeletal protein binding	0.410980330975135	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.262488670799547	bayes_pls_golite062009
kinase activity	0.23220842649445	bayes_pls_golite062009
transferase activity	0.23030640245878	bayes_pls_golite062009
transcription regulator activity	0.221086931523202	bayes_pls_golite062009
DNA binding	0.171056781378569	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.150699828293053	bayes_pls_golite062009
protein kinase activity	0.045934290531206	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..302]	PSI-BLAST	34.69897	Importin alpha

Protein Overview: nero-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: