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Protein Overview: gammaCop-PA

General Information:
Name(s) found: gammaCop-PA / FBpp0085154 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Ã?&#142;Ã?³-coatomer protein is referred to in FlyBase by the symbol Dmel\Ã?&#142;Ã?³Cop (CG1528, FBgn0028968). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:27397865..27401429. It has the cytological map location 100C6. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding; structural molecule activity. There is experimental evidence that it is involved in the biological process</span>: cytokinesis; protein secretion; open tracheal system development; branch fusion, open tracheal system; lumen formation, open tracheal system; chitin-based embryonic cuticle biosynthetic process; phagocytosis, engulfment. 31 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; embryonic/larval lateral trunk; embryonic/larval dorsal trunk; embryonic nervous system; embryonic/larval dorsal branch; denticle belt. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 879 amino acids

    Gene Ontology:
    Cellular Component: Golgi apparatus [IDA]
    COPI vesicle coat [ISS][NAS]
    Biological Process: phagocytosis, engulfment [IMP]
    retrograde vesicle-mediated transport, Golgi to ER [ISS][NAS]
    chitin-based embryonic cuticle biosynthetic process [IMP]
    cytokinesis [IMP]
    intracellular protein transport [IEA]
    branch fusion, open tracheal system [IMP]
    protein secretion [IMP]
    lumen formation, open tracheal system [IMP]
    open tracheal system development [IMP]
    Molecular Function: protein binding [IEA]
    structural molecule activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSFRREKDD EEDAGPSNAY QNLEKTSVLQ ETRTFNETPV NPRKCIHILT KILYLINQGE  60
   61 QLVAREATDC FFAMTKLFQS KDVVLRRMVY LGIKELSSIA EDVIIVTSSL TKDMTGKEDL 120
  121 YRAAAIRALC SITDNTMLQA VERYMKQCIV DKNAAVSCAA LVSSLRLANT AGDVVKRWAN 180
  181 EAQEALNSDN IMVQYHALGL LYHIRKSDRL AVSKLVNKLT RGSLKSPYAV CMLIRIACKL 240
  241 IEEEDIPSEE LSDSPLFTFI ESCLRHKSEM VIYEAAHAIV NLKNTNPRML SPAFSILQLF 300
  301 CSSPKATLRF AAVRTLNKVA MTHPAAVTTC NLDLEGLITD SNRSVATLAI TTLLKTGAES 360
  361 SVERLMKQIS TFVAEISDEF KVVVVQAICA LCTKYPRKHT VLMNFLSGML REEGGLEYKT 420
  421 SIVDTIITII EENADAKESG LSHLCEFIED CEHVSLAVRI LHLLGKEGPF AATPSKYIRF 480
  481 IYNRVILESP IVRAAAVTAM AQFGASCPAL LSNILVLLGR CQMDPDDEVR DRATYYLSIL 540
  541 NSERPELYKN YIIERENCSL ALLEKSLVEH LNGDVDTRFD ISIVPKAAIV KPVIANDVML 600
  601 VTSSAPRPPK ITREEESAAR LAQLPGIQVL GPIHRSTAPI QLTESETEYT VQCIKHIFGQ 660
  661 HVVFQFDCLN TLSDQILENV RVELTLPEGF TTRAVIPCPK LPYNDLQTTF VIVEFPPDAA 720
  721 NSIATFGATL RFVVKDCDPN TGEPESEEGY DDEYMLEDLE LTVADQIQKT RKNNFQVSWD 780
  781 AADSEEWLQA EDTFVLSAVT TLQDAVNTIV KILGLGAANL SENVPEGTHL HTLLCSGTFR 840
  841 GGAEILVRAK LALSEGVTLN LTVRSTDQDV AELITAAIG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..595] PSI-BLAST 91.69897 AP1 clathrin adaptor core
    2 View Details [596..879] PSI-BLAST 75.522879 Structural Identification of a conserved appendage domain in the carboxyl-terminus of the COPI gamma-subunit.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle