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Protein Overview: dj-1beta-PA

General Information:
Name(s) found: dj-1beta-PA / FBpp0085065 [FlyBase]
Description(s) found:
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  • gi|28571932|ref|NP_651825.3| dj-1beta [Drosophila melanogaster] [NCBI NR]
  • gi|28381503|gb|AAF57086.2| dj-1beta [Drosophila melanogaster] [NCBI NR]
  • gi|18642508|dbj|BAB84672.1| DJ-1 beta [Drosophila melanogaster] [NCBI NR]
  • gi|16767998|gb|AAL28218.1| GH09983p [Drosophila melanogaster] [NCBI NR]
  • The gene dj-1Ã?&#142;Ã?² is referred to in FlyBase by the symbol Dmel\dj-1Ã?&#142;Ã?² (CG1349, FBgn0039802). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26632848..26633701. It has the cytological map location 100A5. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: response to oxidative stress; adult locomotory behavior. 15 alleles are reported. The phenotype of these alleles is annotated with: dopaminergic neuron. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG1349-PA translation from_gene[CG1349 dj-1beta FBgn0039802] seq_release:3 mol_weight=21437 cds_boundaries:(3R:26,622,232..26,622,975[+]) aa_length:205 transcript_info:[CG1349-RA seq_release:3] gene_info:[gene symbol:dj-1beta FBgn0039802 gene_boundari [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VA37) CG1349-PA (GH09983p) (DJ-1 beta) [DrosMelano7227.FASTAC.txt]
  • CG1349-PA [Drosophila melanogaster]gi|16767998|gb|AAL28218.1| GH09983p [Drosophila melanogaster]gi|28571932|ref|NP_651825.3| CG1349-PA [Drosophila melanogaster]gi|18642508|dbj|BAB84672.1| DJ-1 beta [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(26632866..26633006,26633070..26633389,26633456..26633612); ID=FBpp0085065; name=dj-1beta-PA; parent=FBgn0039802,FBtr0085703; dbxref=FlyBase:FBpp0085065,FlyBase_Annotation_IDs:CG1349-PA,GB_protein:AAF57086.2,REFSEQ:NP_651825,GB_pr [fly-100309-contam.fasta]
  • CG1349-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • dj-1beta CG1349-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • DJ-1 beta [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GH09983p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • dj-1beta [Drosophila melanogaster] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • type=protein; loc=3R:join(26632866..26633006,26633070..26633389,26633456..26633612); ID=FBpp0085065; name=dj-1beta-PA; parent=FBgn0039802,FBtr0085703; dbxref=FlyBase:FBpp0085065,FlyBase_Annotation_IDs:CG1349-PA,GB_protein:AAF57086.2,REFSEQ:NP_651825,GB_protein:AAF57086; MD5=bcc6527b9257f2fd0c77908e2c88268e; length=205; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(26632866..26633006,26633070..26633389,26633456..26633612); ID=FBpp0085065; name=dj-1beta-PA; parent=FBgn0039802,FBtr0085703; dbxref=FlyBase:FBpp0085065,FlyBase_Annotation_IDs:CG1349-PA,GB_protein:AAF57086.2,REFSEQ:NP_651825,GB_protein:AAF57086; MD5=bcc6527b9257f2fd0c77908e2c88268e; length=205; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • DJ-1 beta OS=Drosophila melanogaster GN=dj-1beta PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:join(26632866..26633006,26633070..26633389,26633456..26633612); ID=FBpp0085065; name=dj-1beta-PA; parent=FBgn0039802,FBtr0085703; dbxref=FlyBase:FBpp0085065,FlyBase_Annotation_IDs:CG1349-PA,GB_protein:AAF57086.2,REFSEQ:NP_651825,GB_protein:AAF57086,FlyMine:FBpp0085065,modMine:FBpp0085065; MD5=bcc6527b9257f2fd0c77908e2c88268e; length=205; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:join(30807144..30807284,30807348..30807667,30807734..30807890); ID=FBpp0085065; name=dj-1beta-PA; parent=FBgn0039802,FBtr0085703; dbxref=FlyBase:FBpp0085065,FlyBase_Annotation_IDs:CG1349-PA,GB_protein:AAF57086.2,REFSEQ:NP_651825,GB_protein:AAF57086,FlyMine:FBpp0085065,modMine:FBpp0085065; MD5=bcc6527b9257f2fd0c77908e2c88268e; length=205; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • DJ-1 beta OS=Drosophila melanogaster GN=dj-1beta PE=1 SV=2 [DROME.fasta.20160308]
    • Organism: Drosophila melanogaster
    Length: 205 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: response to oxidative stress [IDA][IMP]
    adult locomotory behavior [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFFGFPQIS RHFSKFTKMS KSALVILAPG AEEMEFIIAA DVLRRAGIKV TVAGLNGGEA  60
   61 VKCSRDVQIL PDTSLAQVAS DKFDVVVLPG GLGGSNAMGE SSLVGDLLRS QESGGGLIAA 120
  121 ICAAPTVLAK HGVASGKSLT SYPSMKPQLV NNYSYVDDKT VVKDGNLITS RGPGTAYEFA 180
  181 LKIAEELAGK EKVQEVAKGL LVAYN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] PSI-BLAST 38.0 Crystal Structure of Human DJ-1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.30391542469987 bayes_pls_golite062009
  • binding
    		•  1.22860407524238 bayes_pls_golite062009
  • ligase activity
    		•  1.03859358394018 bayes_pls_golite062009
  • peptidase activity
    		•  0.819143099666235 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.3972868364469 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.217251599372912 bayes_pls_golite062009
  • hydrolase activity
    		•  0.121916378202276 bayes_pls_golite062009
  • protein binding
    		•  0.0152024556625711 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.70

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle