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Protein Overview: Npc2g-PA, FBpp02...

General Information:
Name(s) found: FBpp0297402 [FlyBase]
Npc2g-PA / FBpp0085085 [FlyBase]
Description(s) found:
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  • gi|7301976|gb|AAF57081.1| CG11314 [Drosophila melanogaster] [NCBI NR]
  • gi|24651498|ref|NP_651823.1| CG11314 [Drosophila melanogaster] [NCBI NR]
  • type=protein; loc=3R:complement(26570476..26570955); ID=FBpp0297402; name=Npc2g-PB; parent=FBgn0039800,FBtr0306293; dbxref=REFSEQ:NP_001247375,GB_protein:AFH06692,FlyBase:FBpp0297402,FlyBase_Annotation_IDs:CG11314-PB; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r5.56; species=Dmel; [FlyBase]
  • The gene Niemann-Pick type C-2g is referred to in FlyBase by the symbol Dmel\Npc2g (CG11314, FBgn0039800). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26570326..26570983. It has the cytological map location 100A3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mesoderm development. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG11314-PA translation from_gene[CG11314 CG11314 FBgn0039800] seq_release:3 mol_weight=17451 cds_boundaries:(3R:26,559,845..26,560,321[-]) aa_length:159 transcript_info:[CG11314-RA seq_release:3] gene_info:[gene symbol:CG11314 FBgn0039800 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VA42) CG11314 protein [DrosMelano7227.FASTAC.txt]
  • (AE003775) CG11314 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG11314-PA [Drosophila melanogaster]gi|24651498|ref|NP_651823.1| CG11314-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(26570476..26570955); ID=FBpp0085085; name=CG11314-PA; parent=FBgn0039800,FBtr0085723; dbxref=FlyBase:FBpp0085085,FlyBase_Annotation_IDs:CG11314-PA,GB_protein:AAF57081.1,REFSEQ:NP_651823,GB_protein:AAF57081; MD5=66b4bdf22aca [fly-100309-contam.fasta]
  • CG11314-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(26570476..26570955); ID=FBpp0085085; name=CG11314-PA; parent=FBgn0039800,FBtr0085723; dbxref=FlyBase:FBpp0085085,FlyBase_Annotation_IDs:CG11314-PA,GB_protein:AAF57081.1,REFSEQ:NP_651823,GB_protein:AAF57081; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(26570476..26570955); ID=FBpp0085085; name=Npc2g-PA; parent=FBgn0039800,FBtr0085723; dbxref=FlyBase:FBpp0085085,FlyBase_Annotation_IDs:CG11314-PA,GB_protein:AAF57081.1,REFSEQ:NP_651823,GB_protein:AAF57081; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Niemann-Pick type C-2g OS=Drosophila melanogaster GN=Npc2g PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(26570476..26570955); ID=FBpp0085085; name=Npc2g-PA; parent=FBgn0039800,FBtr0085723; dbxref=FlyBase:FBpp0085085,FlyBase_Annotation_IDs:CG11314-PA,GB_protein:AAF57081.1,REFSEQ:NP_651823,GB_protein:AAF57081,FlyMine:FBpp0085085,modMine:FBpp0085085; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(26570476..26570955); ID=FBpp0297402; name=Npc2g-PB; parent=FBgn0039800,FBtr0306293; dbxref=REFSEQ:NP_001247375,GB_protein:AFH06692,FlyBase:FBpp0297402,FlyBase_Annotation_IDs:CG11314-PB; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(30744754..30745233); ID=FBpp0085085; name=Npc2g-PA; parent=FBgn0039800,FBtr0085723; dbxref=FlyBase:FBpp0085085,FlyBase_Annotation_IDs:CG11314-PA,GB_protein:AAF57081.1,REFSEQ:NP_651823,GB_protein:AAF57081,FlyMine:FBpp0085085,modMine:FBpp0085085; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(30744754..30745233); ID=FBpp0297402; name=Npc2g-PB; parent=FBgn0039800,FBtr0306293; dbxref=REFSEQ:NP_001247375,GB_protein:AFH06692,FlyBase:FBpp0297402,FlyBase_Annotation_IDs:CG11314-PB; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(30744754..30745233); ID=FBpp0085085; name=Npc2g-PA; parent=FBgn0039800,FBtr0085723; dbxref=FlyBase:FBpp0085085,FlyBase_Annotation_IDs:CG11314-PA,GB_protein:AAF57081.1,REFSEQ:NP_651823,GB_protein:AAF57081,FlyMine:FBpp0085085,modMine:FBpp0085085; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:complement(30744754..30745233); ID=FBpp0297402; name=Npc2g-PB; parent=FBgn0039800,FBtr0306293; dbxref=REFSEQ:NP_001247375,GB_protein:AFH06692,FlyBase:FBpp0297402,FlyBase_Annotation_IDs:CG11314-PB; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Niemann-Pick type C-2g, isoform A OS=Drosophila melanogaster GN=Npc2g PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0085085 type=protein; loc=3R:complement(30744754..30745233); ID=FBpp0085085; name=Npc2g-PA; parent=FBgn0039800,FBtr0085723; dbxref=FlyBase:FBpp0085085,FlyBase_Annotation_IDs:CG11314-PA,GB_protein:AAF57081.1,REFSEQ:NP_651823,GB_protein:AAF57081,FlyMine:FBpp0085085,modMine:FBpp0085085; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0297402 type=protein; loc=3R:complement(30744754..30745233); ID=FBpp0297402; name=Npc2g-PB; parent=FBgn0039800,FBtr0306293; dbxref=REFSEQ:NP_001247375,GB_protein:AFH06692,FlyBase:FBpp0297402,FlyBase_Annotation_IDs:CG11314-PB; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(30744754..30745233); ID=FBpp0085085; name=Npc2g-PA; parent=FBgn0039800,FBtr0085723; dbxref=FlyBase:FBpp0085085,FlyBase_Annotation_IDs:CG11314-PA,GB_protein:AAF57081.1,REFSEQ:NP_651823,GB_protein:AAF57081,UniProt/TrEMBL:Q9VA42,FlyMine:FBpp0085085,modMine:FBpp0085085; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:complement(30744754..30745233); ID=FBpp0297402; name=Npc2g-PB; parent=FBgn0039800,FBtr0306293; dbxref=REFSEQ:NP_001247375,GB_protein:AFH06692,FlyBase:FBpp0297402,FlyBase_Annotation_IDs:CG11314-PB,UniProt/TrEMBL:Q9VA42; MD5=66b4bdf22aca5935398d91eb24da6918; length=159; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 159 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: mesoderm development [IEP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRPSSLQAV AIAIVLISSS ASAEVVNFEP CPDSVDTCTI QQVRVSPCPE ALNNAACNIR  60
   61 RKHNSEMSFD FTPNFDADTL VASLGWAKSE NVELPLLTLD SAACKYTPCP VRSGVKQTYT 120
  121 TLVPIEAKFP LSPYTIRWAL KDPVSQKRCC FTIDIKVVR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] PSI-BLAST 39.69897 Epididymal secretory protein E1 (Niemann-Pick C2 protein)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.879052093832773 bayes_pls_golite062009
  • protein binding
    		•  0.80731472263402 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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