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Protein Overview: Nlp-PA, FBpp0306756

General Information:
Name(s) found: FBpp0306756 [FlyBase]
Nlp-PA / FBpp0084918 [FlyBase]
Description(s) found:
Found 33 descriptions.
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  • type=protein; loc=3R:join(25830756..25830777,25831010..25831143,25835400..25835702); ID=FBpp0306756; name=Nlp-PB; parent=FBgn0016685,FBtr0334701; dbxref=FlyBase:FBpp0306756,FlyBase_Annotation_IDs:CG7917-PB,REFSEQ:NP_001263094,GB_protein:AGB96473; MD5=dc47741a9538770e46fb5476f6fca20d; length=152; release=r5.56; species=Dmel; [FlyBase]
  • The gene Nucleoplasmin is referred to in FlyBase by the symbol Dmel\Nlp (CG7917, FBgn0016685). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25830507..25836074. It has the cytological map location 99D1. There is experimental evidence that it has the molecular function</span>: SUMO binding. It is reported to be involved in the biological process</span>: nucleosome positioning. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 152 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    nucleolus [IDA]
    Biological Process: nucleosome positioning [NAS]
    Molecular Function: nucleic acid binding [IEA]
    SUMO binding [IPI]
    histone binding [NAS][TAS]
    ATPase activity, coupled [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEESFYGVT LTAESDSVTW DVDEDYARGQ KLVIKQILLG AEAKENEFNV VEVNTPKDSV  60
   61 QIPIAVLKAG ETRAVNPDVE FYESKVTFKL IKGSGPVYIH GHNIKDDVEV VDMEEDDEED 120
  121 DVAEDEEDEH PKKRAKIENA ADGKNAKNNK KK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] PSI-BLAST 36.0 Chromatin decondensation protein 1 (Crp1, Nlp)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • histone binding
    		•  3.73631008078015 bayes_pls_golite062009
  • binding
    		•  2.19692759714478 bayes_pls_golite062009
  • transcription factor binding
    		•  1.4976713920008 bayes_pls_golite062009
  • protein binding
    		•  1.3440114925508 bayes_pls_golite062009
  • Tat protein binding
    		•  0.996703573687181 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.395857257483946 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.174072284800949 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle