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Protein Overview: dmrt99B-PA

General Information:
Name(s) found: dmrt99B-PA / FBpp0084820 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene doublesex-Mab related 99B is referred to in FlyBase by the symbol Dmel\dmrt99B (CG15504, FBgn0039683). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25518313..25522747. It has the cytological map location 99B8. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: sex differentiation; regulation of transcription, DNA-dependent. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 510 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: sex differentiation [IEA]
    regulation of transcription, DNA-dependent [IEA]
    Molecular Function: transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPSGVDMQ NLMSQHPVLG ALPPAFFLRA ASERYQRTPK CARCRNHGVV SALKGHKRYC  60
   61 RWRDCVCAKC TLIAERQRVM AAQVALRRQQ AQEENEAREL GLLYTSVPGQ QNGSDSATPT 120
  121 PHSPNHSGSG GSGSGGSGQN GVFHGGIPSP PSDGFEASST PNHHQQSQQQ QQAHHQQHLS 180
  181 HPHQQSQRFN GNESDTDGRT RSEHLSVGFS PTRTELDESP VSKRGAALSN ETDQDTGSES 240
  241 GSPSSPRPKV AGLFNLTASL SPARTGPPSS PESDLDVDSA PDEATPENLS LKKEDSQSPP 300
  301 NTPAENLHLL RSFSSSHAQG FLPYHHTQFL AAAGLPAHHH PAAHSPHHQQ QQQQQQQQQN 360
  361 HLPQHHQQQQ QQQQQQQRSP IDVLMRVFPN RRRSDVEQLM QRFRGDVLQA MECMLAGEDL 420
  421 GQTPPQVPPS PPFPMKSAFS PLVPPSVFGS PTHRYHPFMQ AHAKRFLTAP YAGTGYLPGV 480
  481 LSAADIEQSE SNGAGGIGLD RTSNAGDSQD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..102] PSI-BLAST 21.69897 DM domain of Doublesex (dsx)
    2 View Details [103..212] deduced N/A No confident structure predictions are available.
    3 View Details [213..405] FFAS03 0.961 No description for 2j63A was found.
    4 View Details [406..510] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.01128232423451 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.127098718479447 bayes_pls_golite062009
  • DNA binding
    		•  0.0686553590152803 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle